Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Cláudia Sousa-Mendes"'
1
Akademický článek
Long-Term Exposure to Supraphysiological Levels of Testosterone Impacts Rat Submandibular Gland Proteome
Autor: João Valente-Santos, Rui Vitorino, Cláudia Sousa-Mendes, Paula Oliveira, Bruno Colaço, Ana I. Faustino-Rocha, Maria João Neuparth, Adelino Leite-Moreira, José Alberto Duarte, Rita Ferreira, Francisco Amado
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 1, p 550 (2023)
The salivary glands play a central role in the secretion of saliva, whose composition and volume affect oral and overall health. A lesser-explored dimension encompasses the possible changes in salivary gland proteomes in response to fluctuations in s
Externí odkaz: https://doaj.org/article/04a6cb7ddad7494b891c7bc705798ebe
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3
Akademický článek
Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulation of ET-1 and Upregulation of eNOS
Autor: Ana Filipa Martins, Ana Catarina Neto, Adriana Raquel Rodrigues, Sandra Marisa Oliveira, Cláudia Sousa-Mendes, Adelino Leite-Moreira, Alexandra Maria Gouveia, Henrique Almeida, Delminda Neves
Publikováno v: Biomedicines, Vol 10, Iss 11, p 2782 (2022)
This study aimed to evaluate if the treatment with metformin affects the morphologic structure, endothelial function, angiogenesis, inflammation and oxidation-responsive pathways in the heart of mice with surgically induced endometriosis. B6CBA/F1 mi
Externí odkaz: https://doaj.org/article/e4ec2b7bf18b4def9ac2b00b682e253c
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4
Akademický článek
The Degree of Cardiac Remodelling before Overload Relief Triggers Different Transcriptome and miRome Signatures during Reverse Remodelling (RR)—Molecular Signature Differ with the Extent of RR
Autor: Patrícia G. Rodrigues, Daniela Miranda-Silva, Xidan Li, Cláudia Sousa-Mendes, Ricardo Martins-Ferreira, Zaher Elbeck, Adelino F. Leite-Moreira, Ralph Knöll, Inês Falcão-Pires
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 24, p 9687 (2020)
This study aims to provide new insights into transcriptome and miRome modifications occurring in cardiac reverse remodelling (RR) upon left ventricle pressure-overload relief in mice. Pressure-overload was established in seven-week-old C57BL/6J-mice
Externí odkaz: https://doaj.org/article/70dae3d4d7b8413197232e147a7ab04d
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5
Chronic Sildenafil Therapy in the ZSF1 Obese Rat Model of Metabolic Syndrome and Heart Failure With Preserved Ejection Fraction
Autor: Liliana Moreira-Costa, Francisco Vasques-Nóvoa, Dulce Fontoura, António Angélico-Gonçalves, Rui J Cerqueira, Cláudia Sousa-Mendes, André P. Lourenço, Sara Leite, Adelino F. Leite-Moreira
Publikováno v: Journal of Cardiovascular Pharmacology and Therapeutics. 26:690-701
Although decreased protein kinase G (PKG) activity was proposed as potential therapeutic target in heart failure with preserved ejection fraction (HFpEF), randomized clinical trials (RCTs) with type-5 phosphodiesterase inhibitors (PDE5i) showed neutr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf77da945caa823e0d43e884069ed2a2
https://doi.org/10.1177/10742484211034253
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6
Fat Quality Matters: Distinct Proteomic Signatures Between Lean and Obese Cardiac Visceral Adipose Tissue Underlie its Differential Myocardial Impact
Autor: Daniela Miranda-Silva, Júlia Matos, Inês Falcão-Pires, Cláudia Sousa-Mendes, Nádia Gonçalves, Adelino F. Leite-Moreira, Rita Ferreira, Rui Vitorino, Glória Conceição, Alexandre Gonçalves
Publikováno v: Cellular Physiology and Biochemistry, Vol 54, Iss 3, Pp 384-400 (2020)
Background/aims Heart failure with preserved ejection fraction (HFpEF) is recognised as an important cause of cardiovascular mortality and morbidity, accounting for approximately 50% of heart failure cases. Metabolic-related complications, such as ob
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec299f10d1c6bfcce2489d854405e5b
https://www.cellphysiolbiochem.com/Articles/000226/
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7
The Degree of Cardiac Remodelling before Overload Relief Triggers Different Transcriptome and miRome Signatures during Reverse Remodelling (RR)—Molecular Signature Differ with the Extent of RR
Autor: Adelino F. Leite-Moreira, Inês Falcão-Pires, Daniela Miranda-Silva, Ralph Knöll, Cláudia Sousa-Mendes, Ricardo Martins-Ferreira, Xidan Li, Patrícia Rodrigues, Zaher Elbeck
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9687, p 9687 (2020)
This study aims to provide new insights into transcriptome and miRome modifications occurring in cardiac reverse remodelling (RR) upon left ventricle pressure-overload relief in mice. Pressure-overload was established in seven-week-old C57BL/6J-mice
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66888b3518a097cb82a754edfcef3e8a
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8
Characterization of biventricular alterations in myocardial (reverse) remodelling in aortic bandinginduced chronic pressure overload
Autor: Cláudia Sousa-Mendes, Tânia Lima, Inês Falcão-Pires, Patrícia Gonçalves-Rodrigues, Daniela Miranda-Silva, Glória Conceição, Javier Díez, Arantxa González, Cláudia-Moura, Wolfgang A. Linke, Nazha Hamdani, Adelino F. Leite-Moreira, João Almeida-Coelho
Publikováno v: Scientific Reports
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Aortic Stenosis (AS) is the most frequent valvulopathy in the western world. Traditionally aortic valve replacement (AVR) has been recommended immediately after the onset of heart failure (HF) symptoms. However, recent evidence suggests that AVR outc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9993415e376311464d58e1a1df912b0a
https://hdl.handle.net/10171/62140
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9
Early myocardial changes induced by doxorubicin in the nonfailing dilated ventricle
Autor: Dulce Fontoura, Adelino F. Leite-Moreira, Cláudia Sousa-Mendes, Fábio Trindade, Cláudia Moura, Sofia M. Costa, Nazha Hamdani, Daniela Miranda-Silva, Inês Falcão-Pires, Maria J. Mendes, Wolfgang A. Linke, Patrícia Rodrigues, Rui Vitorino, Carla Barros
Publikováno v: American journal of physiology. Heart and circulatory physiology. 316(3)
Several studies have demonstrated that administration of doxorubicin (DOXO) results in cardiotoxicity, which eventually progresses to dilated cardiomyopathy. The present work aimed to evaluate the early myocardial changes of DOXO-induced cardiotoxici
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3775db6aa86c631d72b65797e5f095
https://pubmed.ncbi.nlm.nih.gov/30525890
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10
Distinct right ventricle remodeling in response to pressure overload in the rat
Autor: P. Mendes-Ferreira, Cláudia Sousa-Mendes, Carmen Brás-Silva, Miguel Mendes-Ferreira, Rui Adão, D. Santos-Ribeiro, Adelino F. Leite-Moreira, C. Maia-Rocha
Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 311:H85-H95
Pulmonary arterial hypertension (PAH), the most serious chronic disorder of the pulmonary circulation, is characterized by pulmonary vasoconstriction and remodeling, resulting in increased afterload on the right ventricle (RV). In fact, RV function i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc29aa62e3eceaf407ab5bc06c5f06c6
https://doi.org/10.1152/ajpheart.00089.2016
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