Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cláudia Saraiva"'
Autor:
Catarina Rebelo, Tiago Reis, Joana Guedes, Cláudia Saraiva, Artur Filipe Rodrigues, Susana Simões, Liliana Bernardino, João Peça, Sónia L. C. Pinho, Lino Ferreira
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Spatial control of gene expression is critical to modulate cellular functions and deconstruct the function of individual genes in biological processes. Light-responsive gene-editing formulations have been recently developed; however, they ha
Externí odkaz:
https://doaj.org/article/c7b23c15dc4c4965aa7f743648a55671
Autor:
Marta Machado-Pereira, Cláudia Saraiva, Liliana Bernardino, Ana C. Cristóvão, Raquel Ferreira
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background The brain vasculature plays a pivotal role in the inflammatory process by modulating the interaction between blood cells and the neurovascular unit. Argonaute-2 (Ago2) has been suggested as essential for endothelial survival but i
Externí odkaz:
https://doaj.org/article/7aaa0f381b604b4a99a42b7d092771eb
Autor:
Catarina Rebelo, Tiago Reis, Joana Guedes, Cláudia Saraiva, Artur Filipe Rodrigues, Susana Simões, Liliana Bernardino, João Peça, Sónia L. C. Pinho, Lino Ferreira
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/83068e9a94e742608c1b26158847f1d9
Autor:
Catarina Serra-Almeida, Cláudia Saraiva, Marta Esteves, Raquel Ferreira, Tiago Santos, Ana Clara Cristóvão, Liliana Bernardino
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
C-terminal binding proteins (CtBPs) are transcriptional modulators that can regulate gene expression through the recruitment of a corepressor complex composed of chromatin-modifying enzymes and transcriptional factors. In the brain, CtBPs have been d
Externí odkaz:
https://doaj.org/article/5eb2ab7c9c684cd58a533131a36d7546
Autor:
Cláudia Saraiva, Daniela Talhada, Akhilesh Rai, Raquel Ferreira, Lino Ferreira, Liliana Bernardino, Karsten Ruscher
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193609 (2018)
There is a high quest for novel therapeutic strategies to enhance recovery after stroke. MicroRNA-124 (miR-124) has been described as neuroprotective and anti-inflammatory molecule. Moreover, miR-124 is a well described enhancer of adult neurogenesis
Externí odkaz:
https://doaj.org/article/03a116568cb44982974ba8c559a95051
Autor:
Cláudia Saraiva, Jéssica Lopes-Nunes, Marta Esteves, Tiago Santos, Ana Vale, Ana Clara Cristóvão, Raquel Ferreira, Liliana Bernardino
Publikováno v:
Molecular Neurobiology.
C-terminal binding proteins (CtBP) are transcriptional co-repressors regulating gene expression. CtBP promote neuronal survival through repression of pro-apoptotic genes, and may represent relevant targets for neurodegenerative disorders, such as Par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32987af129c060a7506677c149ba4411
https://doi.org/10.1007/s12035-023-03331-w
https://doi.org/10.1007/s12035-023-03331-w
Autor:
Kyriaki Barmpa, Claudia Saraiva, Diego Lopez-Pigozzi, Gemma Gomez-Giro, Elisa Gabassi, Sarah Spitz, Konstanze Brandauer, Juan E. Rodriguez Gatica, Paul Antony, Graham Robertson, Rahman Sabahi-Kaviani, Alessandro Bellapianta, Florentia Papastefanaki, Regina Luttge, Ulrich Kubitscheck, Ahmad Salti, Peter Ertl, Mario Bortolozzi, Rebecca Matsas, Frank Edenhofer, Jens C. Schwamborn
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Parkinson’s disease, an aging-associated neurodegenerative disorder, is characterised by nigrostriatal pathway dysfunction caused by the gradual loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. Human in v
Externí odkaz:
https://doaj.org/article/01a3e63dcff24b67a4571fd2ecb5411b
Autor:
Iman Zare, Mohammad Tavakkoli Yaraki, Giorgio Speranza, Alireza Hassani Najafabadi, Alireza Shourangiz-Haghighi, Amirala Bakhshian Nik, Bella B. Manshian, Cláudia Saraiva, Stefaan J. Soenen, Marcelo J. Kogan, Jee Woong Lee, Nicholas V. Apollo, Liliana Bernardino, Eyleen Araya, Dirk Mayer, Guangzhao Mao, Michael R. Hamblin
Publikováno v:
Chemical Society Reviews. 51:2601-2680
Recent advances in technology are expected to increase our current understanding of neuroscience. Nanotechnology and nanomaterials can alter and control neural functionality in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067ad63e7e785913b8f72eaf81cdda77
https://doi.org/10.1039/d1cs01111a
https://doi.org/10.1039/d1cs01111a
Autor:
Marta Esteves, Ricardo Abreu, Hugo Fernandes, Catarina Serra-Almeida, Patrícia A.T. Martins, Marta Barão, Ana Clara Cristóvão, Cláudia Saraiva, Raquel Ferreira, Lino Ferreira, Liliana Bernardino
Publikováno v:
Molecular Therapy, 30(10), 3176-3192. Cell Press
Parkinson's disease is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra with no effective cure available. MicroRNA-124 has been regarded as a promising therapeutic entity for Parkinson's disease du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d151a7a91718b2b8b895d821f29cc005
https://cris.maastrichtuniversity.nl/en/publications/29b8e257-c7a6-45dc-837e-6e176de69ea1
https://cris.maastrichtuniversity.nl/en/publications/29b8e257-c7a6-45dc-837e-6e176de69ea1
Autor:
Sonia Sabate‐Soler, Sarah Louise Nickels, Cláudia Saraiva, Emanuel Berger, Ugne Dubonyte, Kyriaki Barmpa, Yan Jun Lan, Tsukasa Kouno, Javier Jarazo, Graham Robertson, Jafar Sharif, Haruhiko Koseki, Christian Thome, Jay W. Shin, Sally A. Cowley, Jens C. Schwamborn
Publikováno v:
Glia, 70 (7)
The human brain is a complex, three-dimensional structure. To better recapitulate brain complexity, recent efforts have focused on the development of human-specific midbrain organoids. Human iPSC-derived midbrain organoids consist of differentiated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b246392992f89fde06356e76e3b39e1
https://hdl.handle.net/20.500.11850/538276
https://hdl.handle.net/20.500.11850/538276