Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cláudia S Rodrigues"'
Autor:
Violeta Railean, Cláudia S. Rodrigues, Sofia S. Ramalho, Iris A. L. Silva, Jan Bartosch, Carlos M. Farinha, Ines Pankonien, Margarida D. Amaral
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Most of the 2,100 CFTR gene variants reported to date are still unknown in terms of their disease liability in Cystic Fibrosis (CF) and their molecular and cellular mechanism that leads to CFTR dysfunction. Since some rare variants may respond to cur
Externí odkaz:
https://doaj.org/article/c60cd204f58f4cc1ab638f25e1b04263
Autor:
Daniela Antunes, Samuel M. Gonçalves, Vasiliki Matzaraki, Cláudia S. Rodrigues, Relber A. Gonçales, Joana Rocha, Jorge Sáiz, António Marques, Egídio Torrado, Ricardo Silvestre, Fernando Rodrigues, Frank L. van de Veerdonk, Coral Barbas, Mihai G. Netea, Vinod Kumar, Cristina Cunha, Agostinho Carvalho
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The reprogramming of cellular metabolism of immune cells is an essential process in the regulation of antifungal immune responses. In particular, glucose metabolism has been shown to be required for protective immunity against infection with
Externí odkaz:
https://doaj.org/article/b0a04a853a2e437fa43b85af5346826b
Autor:
Rui Lima, Eduardo D. Gomes, Jorge R. Cibrão, Luís A. Rocha, Rita C. Assunção-Silva, Cláudia S. Rodrigues, Andreia Neves-Carvalho, Susana Monteiro, António J. Salgado, Nuno A. Silva
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Spinal cord injury (SCI) leads to dramatic impairments of motor, sensory, and autonomic functions of affected individuals. Following the primary injury, there is an increased release of glutamate that leads to excitotoxicity and further neur
Externí odkaz:
https://doaj.org/article/6381c90cd2744b65acae2876e1faad97
Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity
Autor:
Samuel M. Gonçalves, Cláudio Duarte-Oliveira, Cláudia F. Campos, Vishukumar Aimanianda, Rob ter Horst, Luis Leite, Toine Mercier, Paulo Pereira, Miguel Fernández-García, Daniela Antunes, Cláudia S. Rodrigues, Catarina Barbosa-Matos, Joana Gaifem, Inês Mesquita, António Marques, Nuno S. Osório, Egídio Torrado, Fernando Rodrigues, Sandra Costa, Leo AB. Joosten, Katrien Lagrou, Johan Maertens, João F. Lacerda, António Campos, Gordon D. Brown, Axel A. Brakhage, Coral Barbas, Ricardo Silvestre, Frank L. van de Veerdonk, Georgios Chamilos, Mihai G. Netea, Jean-Paul Latgé, Cristina Cunha, Agostinho Carvalho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Macrophages undergo a Warburg-like switch from oxidative phosphorylation to glycolysis in response to inflammatory stimulus. Here the authors show that fungal melanin can trigger this switch in human macrophages by sequestering calcium in the phagoso
Externí odkaz:
https://doaj.org/article/3f93976354b64ccb90d4f627223c4b88
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2688 (2022)
The multi-organ disease cystic fibrosis (CF) is caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, a cAMP regulated chloride (Cl−) and bicarbonate (HCO3−) ion channel expressed at the apical plasma
Externí odkaz:
https://doaj.org/article/fabce5bbafac46caa456966558e4e50f
Autor:
Manuel M. Vicente, Inês Alves, Joana Gaifem, Cláudia S. Rodrigues, Ângela Fernandes, Ana M. Dias, Jerko Štambuk, Tea Petrović, Pedro Oliveira, Frederico Ferreira‐da‐Silva, Adriana Soares, Nair Seixas, Tiago Teixeira, Luis Malheiro, Miguel M. Abreu, Gordan Lauc, Rui Sarmento e Castro, Salomé S. Pinho
Publikováno v:
European Journal of Immunology. 52:946-957
The nature of the immune responses associated with COVID‐19 pathogenesis and disease severity, as well as the breadth of vaccine coverage and duration of immunity, is still unclear. Given the unpredictability for developing a severe/complicated dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9581f75a319bcc35e98e46db82ec1c31
https://doi.org/10.1002/eji.202149491
https://doi.org/10.1002/eji.202149491
Autor:
Samuel M. Gonçalves, Katrien Lagrou, Cláudia S. Rodrigues, Cláudia F. Campos, Leticia Bernal-Martínez, Fernando Rodrigues, Ricardo Silvestre, Laura Alcazar-Fuoli, Johan A. Maertens, Cristina Cunha, Agostinho Carvalho
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Background: Invasive pulmonary aspergillosis (IPA) is an infection that primarily affects immunocompromised hosts, including hematological patients and stem-cell transplant recipients. The diagnosis of IPA remains challenging, making desirable the av
Externí odkaz:
https://doaj.org/article/8d4b3527b5f849cfb0c180d9fc882c6c
Autor:
null Manuel M. Vicente, null Inês Alves, null Joana Gaifem, null Cláudia S. Rodrigues, null Ângela Fernandes, null Ana M. Dias, null Jerko Štambuk, null Tea Petrović, null Pedro Oliveira, null Frederico Ferreira‐da‐Silva, null Adriana Soares, null Nair Seixas, null Tiago Teixeira, null Luis Malheiro, null Miguel M. Abreu, null Gordan Lauc, null Rui Sarmento e Castro, null Salomé S. Pinho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c83b2e2b3d51075d3915c206b463927
https://doi.org/10.1002/eji.202149491/v3/response1
https://doi.org/10.1002/eji.202149491/v3/response1
Autor:
Margarida C Quaresma, Hugo M Botelho, Ines Pankonien, Cláudia S Rodrigues, Madalena C Pinto, Pau R Costa, Aires Duarte, Margarida D Amaral
Publikováno v:
Life science alliance. 5(9)
Mutations in the CFTR anion channel cause cystic fibrosis (CF) and have also been related to higher cancer incidence. Previously we proposed that this is linked to an emerging role of functional CFTR in protecting against epithelial–mesenchymal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db003ba8284a4b0130690d29f37af31
https://pubmed.ncbi.nlm.nih.gov/35500936
https://pubmed.ncbi.nlm.nih.gov/35500936
Publikováno v:
Computational Science and Its Applications – ICCSA 2021 ISBN: 9783030869724
ICCSA (4)
ICCSA (4)
Neonatal mortality is a major health concern worldwide, and one of the groups of babies that has contributed most to this outcome is the very low birth weight (VLBW) newborns. Knowing the factors that contribute to the death of these babies and havin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448ed7ec694384513933c2ef68ba06c5
https://doi.org/10.1007/978-3-030-86973-1_42
https://doi.org/10.1007/978-3-030-86973-1_42