Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cláudia M. O. Simões"'
Autor:
Jennifer Munkert, Eliza R. Gomes, Lucas L. Marostica, Betânia B. Cota, Cristina L. M. Lopes, Saulo F. Andrade, José D. de Souza Filho, Ricardo J. Alves, Monica C. Oliveira, Fernão C. Braga, Cláudia M. O. Simões, Rodrigo M. Pádua, André L. B. de Barros
Publikováno v:
ACS Omega, Vol 4, Iss 26, Pp 22048-22056 (2019)
Externí odkaz:
https://doaj.org/article/867dfa7dde75476c88ea3fac10b5869a
Autor:
Naira F. Z. Schneider, Claudia Cerella, Jin-Young Lee, Aloran Mazumder, Kyung Rok Kim, Annelise de Carvalho, Jennifer Munkert, Rodrigo M. Pádua, Wolfgang Kreis, Kyu-Won Kim, Christo Christov, Mario Dicato, Hyun-Jung Kim, Byung Woo Han, Fernão C. Braga, Cláudia M. O. Simões, Marc Diederich
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoev
Externí odkaz:
https://doaj.org/article/1962657514af42deb6f0eab6afdc2661
Autor:
Maria Izabel G. Moritz, Lucas Lourenço Marostica, Éverson M. Bianco, Maria Tereza R. Almeida, João L. Carraro, Gabriela M. Cabrera, Jorge A. Palermo, Cláudia M. O. Simões, Eloir P. Schenkel
Publikováno v:
Marine Drugs, Vol 12, Iss 12, Pp 5864-5880 (2014)
Five new polyoxygenated marine steroids—punicinols A–E (1–5)—were isolated from the gorgonian Leptogorgia punicea and characterized by spectroscopic methods (IR, MS, 1H, 13C and 2-D NMR). The five compounds induced in vitro cytotoxic effects
Externí odkaz:
https://doaj.org/article/8b46e536000e42b781d028496e6f8961
Autor:
Vanderléia G. Marini, Silvia M. Martelli, Clarice F. Zornio, Thiago Caon, Cláudia M. O. Simões, Gustavo A. Micke, Marcone A. L. de Oliveira, Vanderlei G. Machado, Valdir Soldi
Publikováno v:
Química Nova, Vol 37, Iss 5, Pp 839-843 (2014)
Biodegradable nanoparticles (NPs) have received considerable attention because of their possible use in the development of strategies for the topical delivery of oils and therapeutic drugs, particularly when drug penetration in dermis is desired. Zei
Externí odkaz:
https://doaj.org/article/6e8564d858d54b25b48aeb50fb4f4591
Autor:
Eloir P. Schenkel, Fernando J. Durán, Cláudia M. O. Simões, Miriam Falkenberg, Jorge A. Palermo, Maria V. Mañalich Arana, Cíntia Lhullier, Izabella T. Silva, Lara A. Zimmermann, Karen L. Lang
Publikováno v:
Marine Drugs, Vol 10, Iss 10, Pp 2254-2264 (2012)
In the present study, the in vitro cytotoxic effects of six semi-synthetic derivatives of elatol (1) and isoobtusol (2) were investigated. Chemical modifications were performed on the hydroxyl groups aiming to get derivatives of different polarity, n
Externí odkaz:
https://doaj.org/article/9eabc32edbb44e15b7a9794d8d2b5c45
Autor:
Naira F. Z. Schneider, Claudia Cerella, Jin-Young Lee, Aloran Mazumder, Kyung Rok Kim, Annelise de Carvalho, Jennifer Munkert, Rodrigo M. Pádua, Wolfgang Kreis, Kyu-Won Kim, Christo Christov, Mario Dicato, Hyun-Jung Kim, Byung Woo Han, Fernão C. Braga, Cláudia M. O. Simões, Marc Diederich
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoev
Autor:
Izabella T Silva, Annelise Carvalho, Karen L Lang, Sabine E Dudek, Dörthe Masemann, Fernando J Durán, Miguel S B Caro, Ulf R Rapp, Viktor Wixler, Eloir P Schenkel, Cláudia M O Simões, Stephan Ludwig
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 10, Iss 2, p e0117794 (2015)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 10, Iss 2, p e0117794 (2015)
Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer showing high resistance to radiation and chemotherapy. Despite the outstanding progress made i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2beac715ec4a967bce3606af0dbc441d
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117794
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117794
Autor:
Izabella T, Silva, Annelise, Carvalho, Karen L, Lang, Sabine E, Dudek, Dörthe, Masemann, Fernando J, Durán, Miguel S B, Caro, Ulf R, Rapp, Viktor, Wixler, Eloir P, Schenkel, Cláudia M O, Simões, Stephan, Ludwig
Publikováno v:
PLoS ONE
Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer showing high resistance to radiation and chemotherapy. Despite the outstanding progress made i
Autor:
Beatriz D M, de Souza, Débora D, Lückemeyer, Wilson T, Felippe, Ana M H, Alves, Cláudia M O, Simões, Mara C S, Felippe
Publikováno v:
Dental traumatology : official publication of International Association for Dental Traumatology. 28(3)
Milk has been studied extensively and has gained wide acceptance as a suitable storage medium capable of maintenance of avulsed teeth that cannot be replanted immediately. The objective of this study was to evaluate whether the renewal of milk as a s
Autor:
Débora D, Lückemeyer, Vanessa D M, Müller, Maria Izabel G, Moritz, Patricia H, Stoco, Eloir P, Schenkel, Célia R M, Barardi, Flávio H, Reginatto, Cláudia M O, Simões
Publikováno v:
Phytotherapy research : PTR. 26(4)
The antiherpes effects of the crude extract obtained from Ilex paraguariensis leaves (yerba mate) and their purified fractions were investigated. The most active fraction was selected and assayed to determine the viral multiplication steps upon which