Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences

Autor: THOMAS HURLEY, Wf, Bosron, Cl, Stone, Lm, Amzel

Publikováno v: Europe PubMed Central

The three-dimensional structures of three variants of human beta alcohol dehydrogenase have been determined to 2.5 A resolution. These three structures differ only in the amino acid at position 47 and the molecules occupying the alcohol binding site.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50432e0673e8fcd3d826430e6de4f4a5
http://europepmc.org/abstract/med/8201622

X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding

Autor: Gj, Davis, Wf, Bosron, Cl, Stone, Owusu-Dekyi K, THOMAS HURLEY

Publikováno v: Europe PubMed Central

The three-dimensional structure of the human beta3beta3 dimeric alcohol dehydrogenase (beta3) was determined to 2.4-A resolution. beta3 was crystallized as a ternary complex with the coenzyme NAD+ and the competitive inhibitor 4-iodopyrazole. beta3 i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::16db174ac29cd0984b0b823a35772671
http://europepmc.org/abstract/med/8663387

Repurposing the Fourth Year of General Psychiatry Training and Solutions Toward Subspecialty Shortages.

Autor: Stone CL; Thomas Jefferson University Hospital, Philadelphia, PA, USA. cooper.stone@jefferson.edu.

Publikováno v: Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry [Acad Psychiatry] 2024 Oct; Vol. 48 (5), pp. 532-533. Date of Electronic Publication: 2023 Dec 19.

Predictive Value of Isolated Symptoms for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children Tested During Peak Circulation of the Delta Variant.

Autor: Westbrook AL; Pediatric Biostatistics Core, Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Benedit LC; Department of Clinical Research, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Frediani JK; Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA., Griffiths MA; Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Khan NY; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Levy JM; Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia, USA., Morris CR; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Division of Pediatric Emergency Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Rostad CA; Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Stone CL; Department of Clinical Research, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Sullivan J; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Vos MB; Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Welsh J; Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA., Wood A; Pediatric Biostatistics Core, Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Martin GS; Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Lam W; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta, Atlanta, Georgia, USA.; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, USA., Pollock NR; Department of Laboratory Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Sep 30; Vol. 75 (7), pp. 1131-1139.

A unity of opposites: A prototypical case for the importance of primary-care providers in addressing mental health issues.

Autor: Lamm KM; Department of Psychiatry, Cape Fear Valley Medical Center, Fayetteville, United States.; Associate Program Director for the Cape Fear Valley Psychiatric Residency Program with Campbell University, Fayetteville, United States.; Jerry M. Wallace School of Osteopathic Medicine, Lillington, NC, United States., Stone CL; Department of Research, Campbell University School of Osteopathic Medicine, Lillington, NC, University of Mary Washington, Fredericksburg, VA, United States., Rebon G; University of California Santa Barbara, Santa Barbara, CA United States.

Publikováno v: Journal of family medicine and primary care [J Family Med Prim Care] 2020 Aug 25; Vol. 9 (8), pp. 4412-4414. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).