Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ciyu Yang"'
Autor:
Ozge Ceyhan-Birsoy, Elise Fiala, Satshil Rana, Margaret Sheehan, Jennifer Kennedy, Zarina Yelskaya, Vikas Rai, Yirong Li, Ciyu Yang, Donna Wong, Ivelise Rijo, Jacklyn Casanova, Joshua Somar, Nikita Mehta, Hyeonjin Park, Silvana Ostafi, Kanika Arora, Angelika Padunan, Mark D. Ewalt, Umut Aypar, Panieh Terraf, Maksym Misyura, Sofia Haque, Gerald G. Behr, Tamanna Haque, Maria Sulis, Mark B. Geyer, Christopher Forlenza, Meghan C. Thompson, Maria Carlo, Alicia Latham, Ying Liu, Ahmet Zehir, Rose Brannon, Michael Berger, Luis A Diaz Jr, Ahmet Dogan, Marc Ladanyi, Kseniya Petrova-Drus, Khedoudja Nafa, Kenneth Offit, Maria Arcila, Zsofia K. Stadler, Michael F. Walsh, Diana Mandelker
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/f666218e110145a987b006840114e720
Autor:
Diana Mandelker, Antonio Marra, Nikita Mehta, Pier Selenica, Zarina Yelskaya, Ciyu Yang, Joshua Somar, Miika Mehine, Maksym Misyura, Olca Basturk, Alicia Latham, Maria Carlo, Michael Walsh, Zsofia K. Stadler, Kenneth Offit, Chaitanya Bandlamudi, Meera Hameed, Ping Chi, Jorge S. Reis-Filho, Ozge Ceyhan-Birsoy
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Traditional genetic testing for patients with gastrointestinal stromal tumors (GISTs) focus on those with syndromic features. To assess whether expanded genetic testing of GIST patients could identify hereditary cancer predisposition, we ana
Externí odkaz:
https://doaj.org/article/8ed49bc9d2174d23ac73af0621960d66
Autor:
Ozge Ceyhan-Birsoy, Gowtham Jayakumaran, Yelena Kemel, Maksym Misyura, Umut Aypar, Sowmya Jairam, Ciyu Yang, Yirong Li, Nikita Mehta, Anna Maio, Angela Arnold, Erin Salo-Mullen, Margaret Sheehan, Aijazuddin Syed, Michael Walsh, Maria Carlo, Mark Robson, Kenneth Offit, Marc Ladanyi, Jorge S. Reis-Filho, Zsofia K. Stadler, Liying Zhang, Alicia Latham, Ahmet Zehir, Diana Mandelker
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Genetic testing (GT) for hereditary cancer predisposition is traditionally performed on selected genes based on established guidelines for each cancer type. Recently, expanded GT (eGT) using large hereditary cancer gene panels unc
Externí odkaz:
https://doaj.org/article/b27ebc51933945dda60cc3917da9b260
Autor:
M Herman Chui, Ciyu Yang, Nikita Mehta, Vikas Rai, Ahmet Zehir, Amir Momeni Boroujeni, Marc Ladanyi, Diana Mandelker
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 1, Pp 14-18 (2022)
Abstract TP53 is one of the most ubiquitously altered genes in human cancer. The biological impact of rare variants, particularly those located within noncoding regions, remains poorly understood. From interrogation of clinical massively parallel seq
Externí odkaz:
https://doaj.org/article/b83220cb08b643ebbfb30e9d28a040ec
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract Background Germline variants in the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, and PMS2) cause Lynch syndrome, an autosomal dominant hereditary cancer susceptibility syndrome. The risk for endometrial cancer is significantly higher i
Externí odkaz:
https://doaj.org/article/5f5b5db9029c43c68562281eb0dd665e
Autor:
Jennifer L. Hay, Erica H. Lee, Stephanie N. Christian, Elizabeth Schofield, Jada G. Hamilton, Ciyu Yang, Bobak Hedayati, Keimya Sadeghi, Mark E. Robson, Allan Halpern, Liying Zhang, Irene Orlow
Publikováno v:
Journal of Skin Cancer, Vol 2022 (2022)
Public access to genetic information is increasing, and community dermatologists may progressively encounter patients interested in genetic testing for melanoma risk. Clarifying potential utility will help plan for this inevitability. We determined i
Externí odkaz:
https://doaj.org/article/ae40dd67f0a2412bbfbd0d680e049af8
Autor:
Azzam Aladdin, Yanhua Yao, Ciyu Yang, Günther Kahlert, Marvi Ghani, Nikolett Király, Anita Boratkó, Karen Uray, Gunnar Dittmar, Krisztina Tar
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1581 (2020)
The Blm10/PA200 family of proteasome activators modulates the peptidase activity of the core particle (20S CP). They participate in opening the 20S CP gate, thus facilitating the degradation of unstructured proteins such as tau and Dnm1 in a ubiquiti
Externí odkaz:
https://doaj.org/article/e26d9fe4c9894e739b27452260182185
Autor:
Sayani Dasgupta, Ciyu Yang, Leandro M Castro, Alexandre K Tashima, Emer S Ferro, Robyn D Moir, Ian M Willis, Lloyd D Fricker
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163312 (2016)
Peptides function as signaling molecules in species as diverse as humans and yeast. Mass spectrometry-based peptidomics techniques provide a relatively unbiased method to assess the peptidome of biological samples. In the present study, we used a qua
Externí odkaz:
https://doaj.org/article/963777c8a9844402ae8af96bb042329c
Autor:
Yanhua Yao, Scott Tsuchiyama, Ciyu Yang, Anne Laure Bulteau, Chong He, Brett Robison, Mitsuhiro Tsuchiya, Delana Miller, Valeria Briones, Krisztina Tar, Anahi Potrero, Bertrand Friguet, Brian K Kennedy, Marion Schmidt
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004968 (2015)
Elevated proteasome activity extends lifespan in model organisms such as yeast, worms and flies. This pro-longevity effect might be mediated by improved protein homeostasis, as this protease is an integral module of the protein homeostasis network. P
Externí odkaz:
https://doaj.org/article/f606e896d6244a9abe38e383f78876be
Autor:
Sayani Dasgupta, Leandro M Castro, Russell Dulman, Ciyu Yang, Marion Schmidt, Emer S Ferro, Lloyd D Fricker
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103604 (2014)
The proteasome cleaves intracellular proteins into peptides. Earlier studies found that treatment of human embryonic kidney 293T (HEK293T) cells with epoxomicin (an irreversible proteasome inhibitor) generally caused a decrease in levels of intracell
Externí odkaz:
https://doaj.org/article/a25220dad1ee422eb2cbd282a3f07f1c