Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Civia Z. Chen"'
Autor:
Shaline V. Fazal, Clara Mutschler, Civia Z. Chen, Mark Turmaine, Chiung-Ya Chen, Yi-Ping Hsueh, Andrea Ibañez-Grau, Andrea Loreto, Angeles Casillas-Bajo, Hugo Cabedo, Robin J. M. Franklin, Roger A. Barker, Kelly R. Monk, Benjamin J. Steventon, Michael P. Coleman, Jose A. Gomez-Sanchez, Peter Arthur-Farraj
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Since SARM1 mutations have been identified in human neurological disease, SARM1 inhibition has become an attractive therapeutic strategy to preserve axons in a variety of disorders of the peripheral (PNS) and central nervous system (CNS). While SARM1
Externí odkaz:
https://doaj.org/article/11212149181f416b8c3e590d274fb1a6
Publikováno v:
Open Biology, Vol 11, Iss 1 (2021)
Myelin sheaths, by supporting axonal integrity and allowing rapid saltatory impulse conduction, are of fundamental importance for neuronal function. In response to demyelinating injuries in the central nervous system (CNS), oligodendrocyte progenitor
Externí odkaz:
https://doaj.org/article/8c189a5b841640e0a64db0229a2d06f2
Autor:
Shaline V. Fazal, Clara Mutschler, Civia Z. Chen, Mark Turmaine, Chiung-Ya Chen, Yi-Ping Hsueh, Andrea Loreto, Angeles Casillas-Bajo, Hugo Cabedo, Robin J.M. Franklin, Roger A. Barker, Kelly R. Monk, Benjamin J. Steventon, Michael P. Coleman, Jose A. Gomez-Sanchez, Peter Arthur-Farraj
SARM1 is a central regulator of programmed axon death and is required to initiate axon self-destruction after traumatic and toxic insults to the nervous system. Abnormal activation of this axon degeneration pathway is increasingly recognized as a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb1fe267175f2f740304601c4e3b108
https://doi.org/10.1101/2022.12.08.519209
https://doi.org/10.1101/2022.12.08.519209
Autor:
Sarah Förster, Tanay Ghosh, Civia Z Chen, Kevin J. Chalut, Björn Neumann, Michael Segel, Adam Young, Panagiotis Tourlomousis, Amar Sharma, Robin J.M. Franklin, Chao Zhao, Juan F. Cubillos, Khalil S. Rawji
Like many adult stem cell populations, the capacity of oligodendrocyte progenitor cells (OPCs) to proliferate and differentiate is substantially impaired with aging. Previous work has shown that tissue-wide transient expression of the pluripotency fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2641e220a6e69363691d562b97aa98fd
https://www.repository.cam.ac.uk/handle/1810/326698
https://www.repository.cam.ac.uk/handle/1810/326698
Publikováno v:
Open Biology, Vol 11, Iss 1 (2021)
Open Biology
Open Biology
Peer reviewed: True
Funder: Multiple Sclerosis Society (MS50)
Funder: Wellcome Trust; Id: http://dx.doi.org/10.13039/100004440
Funder: MRC
Myelin sheaths, by supporting axonal integrity and allowing rapid saltatory impulse conduct
Funder: Multiple Sclerosis Society (MS50)
Funder: Wellcome Trust; Id: http://dx.doi.org/10.13039/100004440
Funder: MRC
Myelin sheaths, by supporting axonal integrity and allowing rapid saltatory impulse conduct