Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ciusa ML"'
Autor:
Ciusa ML, Furi L, Knight D, Decorosi F, Fondi M, Raggi C, Coelho JR, Aragones L, Moce L, Visa P, Freitas AT, Baldassarri L, Fani R, Viti C, Orefici G, Martinez JL, the BIOHYPO Consortium, Morrissey I, Oggioni MR
Publikováno v:
International Journal of Antimicrobial Agents
The widely used biocide triclosan selectively targets FabI, the NADH-dependent trans-2-enoyl-acyl carrier protein reductase, which is an important target for narrow-spectrum antimicrobial drug development. In relation to the growing concern about bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0527f9353b978962312298e83b300f03
https://doi.org/10.1016/j.ijantimicag.2012.04.021
https://doi.org/10.1016/j.ijantimicag.2012.04.021
Autor:
Ciusa, Ml, Furi, L, Knight, D, Decorosi, Francesca, Fondi, Marco, Raggi, C, Coelho, Jr, Aragones, L, Moce, L, Visa, P, Freitas, At, Baldassarri, L, Fani, Renato, Viti, Carlo, Orefici, G, Martinez, Jl, the BIOHYPO Consortium, Morrissey, I, Oggioni, M. R.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______310::06e92130887f380523a8eca7fbf105c8
http://hdl.handle.net/2158/672714
http://hdl.handle.net/2158/672714
Autor:
Ian Morrissey, Maria Laura Ciusa, Marco R. Oggioni, Stephen L. Leib, Leonardo Furi, Daniel R. Knight, Carlo R. Largiadèr, Lucilla Baldassarri, Denis Grandgirard
Publikováno v:
Grandgirard, Denis; Furi, Leonardo; Ciusa, Maria Laura; Baldassarri, Lucilla; Knight, Daniel R; Morrissey, Ian; Largiadèr, Carlo Rodolfo; Leib, Stephen; Oggioni, Marco R (2015). Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression. BMC Genomics, 16(345), p. 345. BioMed Central 10.1186/s12864-015-1544-y
BMC Genomics
BMC Genomics
Background The enoyl-acyl carrier protein (ACP) reductase enzyme (FabI) is the target for a series of antimicrobial agents including novel compounds in clinical trial and the biocide triclosan. Mutations in fabI and heterodiploidy for fabI have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd2cbd16f9feaaf2a21dd9554419535
Autor:
Ian Morrissey, Lluis Aragones, Valeria Di Lorenzo, Daniela Cirasola, Nadia Tocci, Maria Laura Ciusa, Leonardo Furi, Marco R. Oggioni, Carlo Viti, Daniel R. Knight, Ana T. Freitas, Emmanuela Marchi, Pilar Visa, Laura Moce, Joana Rosado Coelho, John Blackman Northwood, Elisa Borghi, Graziella Orefici
Publikováno v:
Antimicrobial agents and chemotherapy. 57(8)
The MICs and minimum bactericidal concentrations (MBCs) for the biocides benzalkonium chloride and chlorhexidine were determined against 1,602 clinical isolates of Staphylococcus aureus . Both compounds showed unimodal MIC and MBC distributions (2 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cfa5d28dfb6b3dce3903024ed2a960
https://pubmed.ncbi.nlm.nih.gov/23669380
https://pubmed.ncbi.nlm.nih.gov/23669380
Autor:
Francesca Decorosi, Gianni Pozzi, Francesco Iannelli, Nadia Tocci, Alessandro Bidossi, Susanna Ricci, Marco R. Oggioni, Carlo Viti, Maria Laura Ciusa
Publikováno v:
Antimicrobial Agents and Chemotherapy; Vol 57
The pneumococcal chromosome encodes about 140 transporters, many of which are predicted to be involved in efflux. In order to critically evaluate pneumococcal efflux, a series of transporter mutants were constructed, and their phenotypes were assayed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5919d46b1f25bfb39101131049fb96b
http://hdl.handle.net/11585/848728
http://hdl.handle.net/11585/848728
Autor:
Maria Laura Ciusa, Ian Morrissey, Leonardo Furi, Elisa Borghi, Daniela Cirasola, José L. Martínez, Graziella Orefici, Lucilla Baldassarri, Marco R. Oggioni
Publikováno v:
Antimicrobial Agents and Chemotherapy
Subeffective exposure of Staphylococcus aureus to the biocide triclosan can reportedly induce a small-colony variant (SCV) phenotype. S. aureus SCVs are characterized by low growth rates, reduced pigmentation, and lowered antimicrobial susceptibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf6bb928c7ed18280c07610b3776ee
Autor:
Rabiey M; School of Life Sciences, Gibbet Hill Campus, University of Warwick, Coventry, UK.; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Grace ER; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Pawlos P; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Bihi M; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Ahmed H; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Hampson GE; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Al Riyami A; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Alharbi L; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Sanchez-Lucas R; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Korotania N; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Ciusa ML; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Mosley O; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Hulin MT; Department of Plant Soil & Microbial Sciences, Michigan State University, East Lansing, Michigan, USA., Baxter L; Bioinformatics Research Technology Platform, University of Warwick, Coventry, UK., Dhaouadi S; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Vinchira-Villarraga D; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK., Jackson RW; School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, UK.
Publikováno v:
Microbial biotechnology [Microb Biotechnol] 2024 Jun; Vol. 17 (6), pp. e14489.
Autor:
Ciusa ML; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Marshall RL; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Ricci V; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Stone JW; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Piddock LJV; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Publikováno v:
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2022 Feb 23; Vol. 77 (3), pp. 633-640.
Autor:
Marshall RL; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Lloyd GS; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Lawler AJ; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Element SJ; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Kaur J; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Ciusa ML; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Ricci V; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Tschumi A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Kühne H; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Alderwick LJ; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom., Piddock LJV; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom l.j.v.piddock@bham.ac.uk.
Publikováno v:
MBio [mBio] 2020 Jul 14; Vol. 11 (4). Date of Electronic Publication: 2020 Jul 14.
Autor:
Grimsey EM; Antimicrobials Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, Institute of Microbiology and Infection, The University of Birmingham, Birmingham, United Kingdom., Fais C; Department of Physics, University of Cagliari, Monserrato, Italy., Marshall RL; Antimicrobials Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, Institute of Microbiology and Infection, The University of Birmingham, Birmingham, United Kingdom., Ricci V; Antimicrobials Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, Institute of Microbiology and Infection, The University of Birmingham, Birmingham, United Kingdom., Ciusa ML; Antimicrobials Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, Institute of Microbiology and Infection, The University of Birmingham, Birmingham, United Kingdom., Stone JW; Antimicrobials Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, Institute of Microbiology and Infection, The University of Birmingham, Birmingham, United Kingdom., Ivens A; Centre for Immunity, Infection and Evolution, University of Edinburgh Ashworth Labs, Edinburgh, United Kingdom., Malloci G; Department of Physics, University of Cagliari, Monserrato, Italy., Ruggerone P; Department of Physics, University of Cagliari, Monserrato, Italy., Vargiu AV; Department of Physics, University of Cagliari, Monserrato, Italy vargiu@dsf.unica.it L.J.V.PIDDOCK@bham.ac.uk.; Bijvoet Center for Biomolecular Research, Faculty of Science-Chemistry, Utrecht University, Utrecht, The Netherlands., Piddock LJV; Antimicrobials Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, Institute of Microbiology and Infection, The University of Birmingham, Birmingham, United Kingdom vargiu@dsf.unica.it L.J.V.PIDDOCK@bham.ac.uk.
Publikováno v:
MBio [mBio] 2020 Jun 02; Vol. 11 (3). Date of Electronic Publication: 2020 Jun 02.