A CD4+ T cell reference map delineates subtype-specific adaptation during acute and chronic viral infections

Autor: Andreatta, M., Tjitropranoto, A., Sherman, Z., Kelly, M.C., Ciucci, T., Carmona, S.J.

Publikováno v: eLife, vol. 11, pp. e76339

CD4 + T cells are critical orchestrators of immune responses against a large variety of pathogens, including viruses. While multiple CD4 + T cell subtypes and their key transcriptional regulators have been identified, there is a lack of consistent de

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Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis.

Autor: Madel MB; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Halper J; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Ibáñez L; Department of Pharmacy, Cardenal Herrera-CEU University, Valencia, Spain., Claire L; IRMB, Université Montpellier, Montpellier, France., Rouleau M; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Boutin A; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Mahler A; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Pontier-Bres R; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France.; Centre Scientifique, de Monaco, Monaco., Ciucci T; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, United States., Topi M; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Hue C; Université Paris-Saclay, UVSQ, INSERM, Infection et inflammation, Montigny-Le-Bretonneux, France., Amiaud J; Inserm, Universite de Nantes, Nantes, France., Iborra S; Department of Immunology, Ophthalmology and ENT. School of Medicine, Universidad Complutense de Madrid, Madrid, Spain., Sancho D; Immunobiology Laboratory, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Heymann D; Université de Nantes, Institut de Cancérologie de l'Ouest, Saint Herblain, France., Garchon HJ; Université Paris-Saclay, UVSQ, INSERM, Infection et inflammation, Montigny-Le-Bretonneux, France.; Genetics Division, Ambroise Paré Hospital, AP-HP, Boulogne-Billancourt, France., Czerucka D; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France.; Centre Scientifique, de Monaco, Monaco., Apparailly F; IRMB, Université Montpellier, Montpellier, France., Duroux-Richard I; IRMB, Université Montpellier, Montpellier, France., Wakkach A; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France., Blin-Wakkach C; Université Côte d'Azur, CNRS, LP2M, Nice, France.; LIA ROPSE, Laboratoire International Associé Université Côte d'Azur - Centre Scientifique de Monaco, Nice and Monaco, France.

Publikováno v: ELife [Elife] 2023 Feb 27; Vol. 12. Date of Electronic Publication: 2023 Feb 27.

NuRD complex recruitment to Thpok mediates CD4 ⁺ T cell lineage differentiation.

Autor: Gao Y; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Zamisch M; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Vacchio M; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Chopp L; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.; Immunology Graduate Group, University of Pennsylvania Medical School, Philadelphia, PA, USA., Ciucci T; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Paine EL; Collaborative Protein Technology Resource, Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Lyons GC; Collaborative Protein Technology Resource, Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Nie J; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Xiao Q; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Zvezdova E; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Love PE; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Vinson CR; Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Jenkins LM; Immunology Graduate Group, University of Pennsylvania Medical School, Philadelphia, PA, USA., Bosselut R; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.

Publikováno v: Science immunology [Sci Immunol] 2022 Jun 10; Vol. 7 (72), pp. eabn5917. Date of Electronic Publication: 2022 Jun 10.

The transcription factor LRF promotes integrin β7 expression by and gut homing of CD8αα ⁺ intraepithelial lymphocyte precursors.

Autor: Nie J; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Carpenter AC; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA.; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD, USA., Chopp LB; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA.; Immunology Graduate Group, University of Pennsylvania Medical School, Philadelphia, PA, USA., Chen T; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Balmaceno-Criss M; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Ciucci T; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA.; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA., Xiao Q; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Kelly MC; CCR Single Analysis Facility, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Bethesda, MD, USA., McGavern DB; Viral Immunology and Intravital Imaging Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Belkaid Y; Metaorganism Immunology Section, Laboratory of Immune System Biology, Bethesda, MD, USA.; Microbiome core, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD, USA., Bosselut R; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA. bosselur@nih.gov.

Publikováno v: Nature immunology [Nat Immunol] 2022 Apr; Vol. 23 (4), pp. 594-604. Date of Electronic Publication: 2022 Mar 30.

Cross-protective immunity following coronavirus vaccination and coronavirus infection.

Autor: Dangi T; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Palacio N; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Sanchez S; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Park M; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Class J; Department of Microbiology and Immunology, University of Illinois at Chicago (UIC), Chicago, Illinois, USA., Visvabharathy L; Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Ciucci T; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester, Rochester, New York, USA.; Department of Microbiology and Immunology, Center for Vaccine Biology and Immunology, University of Rochester, Rochester, New York, USA., Koralnik IJ; Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Richner JM; Department of Microbiology and Immunology, University of Illinois at Chicago (UIC), Chicago, Illinois, USA., Penaloza-MacMaster P; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Dec 15; Vol. 131 (24).