Scalable integration of multiomic single cell data using Generative Adversarial Networks

Autor: Giansanti, V, Morelli, L, Tonon, G, Cittaro, D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1299::fb87b312f3795a284738afe6916a7b3e
http://hdl.handle.net/10281/394975

Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin.

Autor: Tedesco M; Università Vita-Salute San Raffaele, Milano, Italy.; Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Giannese F; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy., Lazarević D; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy., Giansanti V; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy.; Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milano, Italy., Rosano D; Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy.; Department of Surgery and Cancer, Imperial College London, London, UK., Monzani S; Biochemistry and Structural Biology Unit, Department of Experimental Oncology, IEO, IRCCS European Institute of Oncology, Milano, Italy., Catalano I; Department of Oncology, University of Torino School of Medicine, Candiolo, Torino, Italy.; Candiolo Cancer Institute FPO- IRCCS, Candiolo, Torino, Italy., Grassi E; Department of Oncology, University of Torino School of Medicine, Candiolo, Torino, Italy.; Candiolo Cancer Institute FPO- IRCCS, Candiolo, Torino, Italy., Zanella ER; Candiolo Cancer Institute FPO- IRCCS, Candiolo, Torino, Italy., Botrugno OA; Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Morelli L; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy., Panina Bordignon P; Università Vita-Salute San Raffaele, Milano, Italy.; Neuroimmunology Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Hospital, Milano, Italy., Caravagna G; Department of Mathematics and Geosciences, University of Trieste, Trieste, Italy., Bertotti A; Department of Oncology, University of Torino School of Medicine, Candiolo, Torino, Italy.; Candiolo Cancer Institute FPO- IRCCS, Candiolo, Torino, Italy., Martino G; Università Vita-Salute San Raffaele, Milano, Italy.; Neuroimmunology Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Hospital, Milano, Italy., Aldrighetti L; Hepatobiliary Surgery Division, IRCCS San Raffaele Hospital, Milano, Italy., Pasqualato S; Biochemistry and Structural Biology Unit, Department of Experimental Oncology, IEO, IRCCS European Institute of Oncology, Milano, Italy., Trusolino L; Department of Oncology, University of Torino School of Medicine, Candiolo, Torino, Italy.; Candiolo Cancer Institute FPO- IRCCS, Candiolo, Torino, Italy., Cittaro D; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy. cittaro.davide@hsr.it., Tonon G; Functional Genomics of Cancer Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy. tonon.giovanni@hsr.it.; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy. tonon.giovanni@hsr.it.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2022 Feb; Vol. 40 (2), pp. 235-244. Date of Electronic Publication: 2021 Oct 11.

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing.

Autor: Migliara A; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute; migliara.alessandro@hsr.it., Cappelluti MA; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute., Giannese F; Center for Omics Sciences, IRCCS San Raffaele Institute., Valsoni S; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute., Coglot A; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute., Merelli I; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute; Institute for Biomedical Technologies, National Research Council., Cittaro D; Center for Omics Sciences, IRCCS San Raffaele Institute., Lombardo A; San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute; Vita-Salute San Raffaele University; lombardo.angelo@hsr.it.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2023 May 05 (195). Date of Electronic Publication: 2023 May 05.

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Contrast subgraphs allow comparing homogeneous and heterogeneous networks derived from omics data.

Autor: Lanciano T; Sapienza University of Rome, Rome 00185, Italy., Savino A; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Turin 10126, Italy., Porcu F; Sapienza University of Rome, Rome 00185, Italy., Cittaro D; Center for Omics Sciences, San Raffaele Scientific Institute IRCSS, Milan 20132, Italy., Bonchi F; CENTAI Institute, Corso Inghilterra 3, Turin 10138, Italy., Provero P; Center for Omics Sciences, San Raffaele Scientific Institute IRCSS, Milan 20132, Italy.; Department of Neurosciences 'Rita Levi Montalcini,' University of Turin, Turin 10126, Italy.

Publikováno v: GigaScience [Gigascience] 2022 Dec 28; Vol. 12. Date of Electronic Publication: 2023 Feb 28.