Zobrazeno 1 - 10
of 571
pro vyhledávání: '"Cisplatin-resistant"'
Autor:
Wataru Fukumoto, Shunsuke Okamura, Motoki Tamai, Junya Arima, Ichiro Kawahara, Ikumi Fukuda, Akihiko Mitsuke, Takashi Sakaguchi, Satoshi Sugita, Ryosuke Matsushita, Shuichi Tatarano, Yasutoshi Yamada, Masayuki Nakagawa, Hideki Enokida, Hirofumi Yoshino
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Chemotherapy including cisplatin is recommended for the treatment of advanced bladder cancer, but its effectiveness is limited due to the acquisition of drug resistance. Although several mechanisms of cisplatin resistance have bee
Externí odkaz:
https://doaj.org/article/7d46651dce6b448899636a311a74c173
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Purpose To investigate the role of prognostic genes related to cisplatin resistance in ovarian cancer during disease progression. Method The gene expression profile of the NCI-60 cell line was acquired through comprehensive analysis of the G
Externí odkaz:
https://doaj.org/article/27f062bb574a4fa3bcee0f403f5c7e03
Publikováno v:
Molecular and Cellular Probes, Vol 77, Iss , Pp 101977- (2024)
Objective: Utilizing transcriptome analysis to investigate the mechanisms and therapeutic approaches for cisplatin resistance in non-small cell lung cancer (NSCLC). Methods: Firstly, the biological characters of A549 cells and A549/DDP cells were det
Externí odkaz:
https://doaj.org/article/fea26f2628dc456e8f09da5ce9108b8e
Autor:
Teng Xu, Yuemei Yang, Zhihong Chen, Jinsong Wang, Xiaolei Wang, Yang Zheng, Chao Wang, Yachen Wang, Zaiou Zhu, Xu Ding, Junbo Zhou, Gang Li, Hongchuang Zhang, Wei Zhang, Yunong Wu, Xiaomeng Song
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background Drug resistance limits the treatment effect of cisplatin-based chemotherapy in head and neck squamous cell carcinoma (HNSCC), and the underlying mechanism is not fully understood. The aim of this study was to explore the cause of
Externí odkaz:
https://doaj.org/article/fb0f2cab5c354968ade43b4cea2cc109
Publikováno v:
BMC Oral Health, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Studies have shown that excessive iron can lead to an increased incidence of cancer. The role of adipocyte enhancer-binding protein 1 (AEBP1) on ferroptosis is unknown. Thus, we explored the effect of AEBP1 silencing in regulation
Externí odkaz:
https://doaj.org/article/2d26ea0ac8b0454c850f5ac3144389a6
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Yuan-Qing Qu, Lin-Lin Song, Su-Wei Xu, Margaret Sum Yee Yu, Onat Kadioglu, Francesco Michelangeli, Betty Yuen Kwan Law, Thomas Efferth, Christopher Wai-Kei Lam, Vincent Kam Wai Wong
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106769- (2023)
Drug resistance in cancer has been classified as innate resistance or acquired resistance, which were characterized by apoptotic defects and ABC transporters overexpression respectively. Therefore, to preclude or reverse these resistance mechanisms c
Externí odkaz:
https://doaj.org/article/10230bf769b548b5a26383027eeef547
Autor:
Longxia Li, Di He, Qianqian Guo, Zhiyoung Zhang, Dan Ru, Liting Wang, Ke Gong, Fangfang Liu, Yourong Duan, He Li
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Background Although cisplatin-based chemotherapy has been used as the first-line treatment for ovarian cancer (OC), tumor cells develop resistance to cisplatin during treatment, causing poor prognosis in OC patients. Studies have demonstrate
Externí odkaz:
https://doaj.org/article/e1da2e8f93d1465da0600b0c24955860