Tertiary lymphoid structures in pancreatic cancer are structurally homologous, share gene expression patterns and B-cell clones with secondary lymphoid organs but show increased T-cell activation.

Autor: Lehmann J; University of Cologne, Cologne, Germany., Thelen M; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Kreer C; Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Schran S; University Hospital Cologne, Cologne, NRW, Germany., García-Marquez MA; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Cologne, NRW, Germany., Cisic I; University of Cologne, Cologne, Germany., Siepmann K; University of Cologne, Cologne, Germany., Hagen EM; University of Cologne, Cologne, Germany., Eckel HNC; University of Cologne, Cologne, Germany., Lohneis P; University of Cologne, Cologne, Germany., Kruger S; University Hospital, Ludwig Maximilians University, Munich, Germany., Boeck S; Klinikum Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany., Ormanns S; Tirol Kliniken, Innsbruck, Austria., Rudelius M; Ludwig-Maximilians-Universität München, Munich, Germany., Werner J; University Hospital Heidelberg, Heidelberg, Germany., Popp F; University Hospital Cologne, Cologne, Germany., Klein F; University of Cologne, Germany., von Bergwelt-Baildon MS; Ludwig-Maximilians-University Munich, Munich, Germany., Bruns CJ; Universitätsklinikum Köln, Köln, Germany., Quaas A; University Hospital Cologne, Cologne, Germany., Wennhold K; University Hospital Cologne, Cologne, Germany., Schlößer HA; University Hospital Cologne, Cologne, NRW, Germany.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Dec 11. Date of Electronic Publication: 2024 Dec 11.