Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ciro Santacroce"'
Publikováno v:
Scopus-Elsevier
21, 31-dideoxy- and 2 13 ‘-dideoxy-21, 3 2-didehydrocy- tidine (d2C and d4C) have been synthesized in good yields from 21-deoxyuridine via dichlorinated derivatives 7ab. The same synthetic strategy was used in the synthesis of d2CMeand d4CMefrom th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df61569059189d6fefb8646e5f497646
https://doi.org/10.1080/07328319308018568
https://doi.org/10.1080/07328319308018568
Publikováno v:
ChemInform. 24
The 4-substituted pyrimidine 2′,3′-dideoxy-2′,3′-didehydronucleosides 3 – 10 have been synthesized and the activity of compounds 8 – 10 against HIV evaluated. The synthesis of the 5′-phosphate derivatives 13 – 14 was also reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1235358ac4aa31bf0a3084554b9a7b
https://doi.org/10.1002/chin.199303272
https://doi.org/10.1002/chin.199303272
Autor:
Daniela Montesarchio, M. Varra, Ciro Santacroce, L. De Napoli, Anna Messere, Gennaro Piccialli
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9df7ad0d9bb26cffc83fc6dd4d1ebe91
https://doi.org/10.1002/chin.199433278
https://doi.org/10.1002/chin.199433278
Autor:
L. De Napoli, Daniela Montesarchio, Ciro Santacroce, Gennaro Piccialli, Anna Messere, M. Varra
Publikováno v:
Scopus-Elsevier
Treatment of 3',5'-di-O-acetyl-2'-deoxyinosine 1 with PPh(3)-CCl4 in the presence of catalytic 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) afforded 6-chloro-9-(2'-deoxy-3'.5'-di-O-acenyl-beta-D-ribofuranosyl)purine 3. Use of an excess of DBU gave the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1348a30e567a9bd69ee2f982667fcfeb
https://doi.org/10.1039/p19940000923
https://doi.org/10.1039/p19940000923
Publikováno v:
Scopus-Elsevier
Isoguanosine 1 was obtained in 76% overall yield starting from 2',3',5'-tri-O-acetylxanthosine 3 in a reaction involving the chloro derivative 4 and the N-(purin-6-yl) pyridinium salt derivative 8 which also proved to be new and valuable synthetic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c296939e2007c42c4d424650a18f84
http://hdl.handle.net/11588/155401
http://hdl.handle.net/11588/155401
Publikováno v:
Scopus-Elsevier
A convenient solid-phase synthesis of small cyclic oligoribonucleotides based on elongation of the chain by phosphoramidite chemistry, and successive cyclization of the linear fragments by a phosphotriester approach is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6201ea79c356116d766eb1caf926cbb3
http://hdl.handle.net/11588/145533
http://hdl.handle.net/11588/145533
Autor:
Anna Messere, Ciro Santacroce, Daniela Montesarchio, L. De Napoli, Gennaro Piccialli, G. M. Bonora
Cyclic oligodeoxyribonucleotides have been synthesized in satisfactory yields by an easy procedure using polyethylene glycol (PEG) as soluble supporting polymer. The present method is particularly suitable for a medium to large scale synthesis. Early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb8265cc59b679ed9e74e716da7a461
http://hdl.handle.net/11591/193982
http://hdl.handle.net/11591/193982
The 4-substituted pyrimidine 2′,3′-dideoxy-2′,3′-didehydronucleosides 3 – 10 have been synthesized and the activity of compounds 8 – 10 against HIV evaluated. The synthesis of the 5′-phosphate derivatives 13 – 14 was also reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7136107235fa49790a6be55f251577
http://hdl.handle.net/11591/183319
http://hdl.handle.net/11591/183319
Publikováno v:
Scopus-Elsevier
Reaction of 5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-deoxythymidine with triphenylphosphine/carbon tetrachloride, followed by deprotection of the 5'-hydroxyl group, afforded the 4-chloro derivative 3 from which some 4-substituted pyrimidin-2(1H)one-2'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92488d9a93dda6e7aa10f00495be543d
http://hdl.handle.net/11588/491291
http://hdl.handle.net/11588/491291