Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ciro Bonetti"'
Autor:
Carla P Concepcion, Yoon-Chi Han, Ping Mu, Ciro Bonetti, Evelyn Yao, Aleco D'Andrea, Joana A Vidigal, William P Maughan, Paul Ogrodowski, Andrea Ventura
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002797 (2012)
MicroRNAs belonging to the miR-34 family have been proposed as critical modulators of the p53 pathway and potential tumor suppressors in human cancers. To formally test these hypotheses, we have generated mice carrying targeted deletion of all three
Externí odkaz:
https://doaj.org/article/6caf9841ee7a4deeaf7f26377b954e8b
Autor:
Ciro Bonetti, Enrico Maria Surace
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15211 (2010)
The relative contribution of extrinsic and intrinsic mechanisms to cortical development is an intensely debated issue and an outstanding question in neurobiology. Currently, the emerging view is that interplay between intrinsic genetic mechanisms and
Externí odkaz:
https://doaj.org/article/0364e6b20e494161b1819aa7009d0b0d
Autor:
Marisa Carbonaro, Ciro Bonetti, Hui Huang, Kehui Wang, Mathieu Desclaux, Guochun Gong, John C. Lin, Christopher Daly, Gavin Thurston, Zhe Li
Publikováno v:
Cancer Research. 83:35-35
The incidence of liver cancer is growing worldwide, and it is estimated that by 2025, over 1 million individuals will be affected by liver cancer every year. Hepatocellular carcinoma (HCC) accounts for about 90% of primary liver cancer cases and is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69fb99a24115f491b73f18cd97982817
https://doi.org/10.1158/1538-7445.am2023-35
https://doi.org/10.1158/1538-7445.am2023-35
Autor:
Andrea Ventura, Joana A. Vidigal, Alessandra Crippa, Scott W. Lowe, Paul Ogrodowski, Natasha Rekhtman, Elisa de Stanchina, Danilo Maddalo, Ciro Bonetti, Yoon-Chi Han, Eusebio Manchado, Carla P. Concepcion
Publikováno v:
Nature
Chromosomal rearrangements have a central role in the pathogenesis of human cancers and often result in the expression of therapeutically actionable gene fusions. A recently discovered example is a fusion between the genes echinoderm microtubule-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab546b4e883e9a71452a343c859e9bef
https://doi.org/10.1038/nature13902
https://doi.org/10.1038/nature13902
Autor:
Daniela Sanges, Valeria Marigo, Germana Meroni, Alberto Auricchio, Elena Marrocco, Claudio Mussolino, Ciro Bonetti, Enrico Maria Surace, Umberto Di Vicino
Publikováno v:
EMBO Molecular Medicine; Vol 3
EMBO Molecular Medicine
EMBO Molecular Medicine
Despite the recent success of gene-based complementation approaches for genetic recessive traits, the development of therapeutic strategies for gain-of-function mutations poses great challenges. General therapeutic principles to correct these genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725904eaa6f91bc834cdda9ac068bc61
Autor:
Elena Marrocco, Annagiusi Gargiulo, Enrico Maria Surace, Ciro Bonetti, Alberto Auricchio, Sandro Montefusco, Michele Della Corte, Simona Neglia, Umberto Di Vicino, Luciano Domenici
Publikováno v:
Molecular Therapy. 17:1347-1354
Oculo-cutaneous albinism type 1 (OCA1) is characterized by congenital hypopigmentation and is due to mutations in the TYROSINASE gene (TYR). In this study, we have characterized the morpho-functional consequences of the lack of tyrosinase activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619f95c7fd028f2eb8e9953350802733
https://doi.org/10.1038/mt.2009.112
https://doi.org/10.1038/mt.2009.112
Autor:
Ping Mu, Evelyn Yao, Paul Ogrodowski, Licia Selleri, Christina S. Leslie, Andrea Ventura, Alvaro J. González, Yoon-Chi Han, Brett S. Carver, Ciro Bonetti, Joana A. Vidigal, Doron Betel, Irtisha Singh, Carla P. Concepcion
Publikováno v:
Nature genetics, vol 47, iss 7
Nature genetics
Nature genetics
Polycistronic microRNA (miRNA) clusters are a common feature of vertebrate genomes. The coordinated expression of miRNAs belonging to different seed families from a single transcriptional unit suggests functional cooperation, but this hypothesis has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35011ba583fcece409ba4a47884c41a
https://escholarship.org/uc/item/4wt5g576
https://escholarship.org/uc/item/4wt5g576
Autor:
Carla P. Concepcion, Elisa de Stanchina, Andrea Ventura, Yoon-Chi Han, Natasha Rekhtman, Ciro Bonetti, Eusebio Manchado, Danilo Maddalo, Scott W. Lowe, Paul Ogrodowski, Joana A. Vidigal
Publikováno v:
Journal of Thoracic Oncology. 11(2):S14-S15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d29e246bb85a95b06e3c9916c00425c
Autor:
Ping Mu, Yoon-Chi Han, Paul Ogrodowski, Carla P. Concepcion, Ciro Bonetti, Andrea Ventura, Aleco D'Andrea, Evelyn Yao, Joana A. Vidigal, William P. Maughan
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 8, Iss 7, p e1002797 (2012)
PLoS Genetics, Vol 8, Iss 7, p e1002797 (2012)
MicroRNAs belonging to the miR-34 family have been proposed as critical modulators of the p53 pathway and potential tumor suppressors in human cancers. To formally test these hypotheses, we have generated mice carrying targeted deletion of all three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e2656fa49785c4c175eb2021c8f811
http://europepmc.org/articles/PMC3406012
http://europepmc.org/articles/PMC3406012
Publikováno v:
Cancer journal (Sudbury, Mass.). 18(3)
Overwhelming experimental evidence accumulated over the past decade indicates that microRNAs (miRNAs) are key regulators of gene expression in animals and plants and play important roles in development, homeostasis, and disease. The miR-17-92 family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb92f88c2fc83e6d8fac24e41948a4ba
https://pubmed.ncbi.nlm.nih.gov/22647363
https://pubmed.ncbi.nlm.nih.gov/22647363