Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Ciriaco A Piccirillo"'
Autor:
Gabriel Nathan Kaufman, Amir Hossein Massoud, Marieme eDembele, Madelaine eYona, Ciriaco A Piccirillo, Bruce David Mazer
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
IVIg is a polyclonal IgG preparation with potent immunomodulatory properties. The mode of action of IVIg has been investigated in multiple disease states, with various mechanisms described to account for its benefits. Recent data indicates that IVIg
Externí odkaz:
https://doaj.org/article/505bd7d02b5b4674aed7985e380aca13
Autor:
Gabriel Lachance, Karine Robitaille, Jalal Laaraj, Nikunj Gevariya, Thibault V. Varin, Andrei Feldiorean, Fanny Gaignier, Isabelle Bourdeau Julien, Hui Wen Xu, Tarek Hallal, Jean-François Pelletier, Sidki Bouslama, Nadia Boufaied, Nicolas Derome, Alain Bergeron, Leigh Ellis, Ciriaco A. Piccirillo, Frédéric Raymond, Yves Fradet, David P. Labbé, André Marette, Vincent Fradet
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The gut microbiota modulates response to hormonal treatments in prostate cancer (PCa) patients, but whether it influences PCa progression remains unknown. Here, we show a reduction in fecal microbiota alpha-diversity correlating with increas
Externí odkaz:
https://doaj.org/article/139dc06f836a43328338c482679f75de
Autor:
Mara Kornete, Edward S Mason, Julien Girouard, Erin I Lafferty, Salman Qureshi, Ciriaco A Piccirillo
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126311 (2015)
Type 1 diabetes (T1D) occurs through a breakdown of self-tolerance resulting in the autoimmune destruction of the insulin producing β-islets of the pancreas. A numerical and functional waning of CD4+ Foxp3+ regulatory T (Treg) cells, prompted by a p
Externí odkaz:
https://doaj.org/article/ea3f045a555c4bb49146655c852e2f82
Autor:
JiaMin Huang, Eva Michaud, Surashri Shinde-Jadhav, Sabina Fehric, Gautier Marcq, Jose Joao Mansure, Fabio Cury, Fadi Brimo, Ciriaco A. Piccirillo, Wassim Kassouf
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
MIBC is a highly lethal disease, and the patient survival rate has not improved significantly over the last decades. UPPL is a cell line that can be used to recapitulate the luminal-like molecular subtype of bladder cancer and to discover effective t
Externí odkaz:
https://doaj.org/article/78afd454619d4ec19b99255a2e86a7a4
Autor:
Miroslava Cuperlovic-Culf, Steffany A.L. Bennett, Yannick Galipeau, Pauline S. McCluskie, Corey Arnold, Salman Bagheri, Curtis L. Cooper, Marc-André Langlois, Jörg H. Fritz, Ciriaco A. Piccirillo, Angela M. Crawley
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110484- (2024)
Summary: Prevention of negative COVID-19 infection outcomes is associated with the quality of antibody responses, whose variance by age and sex is poorly understood. Network approaches identified sex and age effects in antibody responses and neutrali
Externí odkaz:
https://doaj.org/article/518eeac978cf4cdfb3505928c36ddd3d
Autor:
Alonso da Silva Lira Filho, Andrea Lafleur, Fernando Alvarez, Ciriaco A. Piccirillo, Martin Olivier
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionExosomes produced by the protozoan parasite Leishmania (LeishEXO) are well-established drivers of virulence, though mechanisms underlying their exacerbation of experimental leishmaniasis remain elusive. Expression of Annexin A1 (ANXA1), a
Externí odkaz:
https://doaj.org/article/17ecd8affece4f35831dfb2b05c5069d
Publikováno v:
Frontiers in Endocrinology, Vol 4 (2013)
There is increasing evidence that dysregulated immune responses play key roles in the pathogenesis and complications of type 1 but also type 2 diabetes. Indeed, chronic inflammation and autoimmunity, which are salient features of type 1 diabetes, are
Externí odkaz:
https://doaj.org/article/1a4451f1301241409cf7577000062c7a
Autor:
Eva Bjur, Ola Larsson, Ekaterina Yurchenko, Lei Zheng, Valentina Gandin, Ivan Topisirovic, Shui Li, Carston R Wagner, Nahum Sonenberg, Ciriaco A Piccirillo
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003494 (2013)
Regulatory T cells expressing the transcription factor Foxp3 play indispensable roles for the induction and maintenance of immunological self-tolerance and immune homeostasis. Genome-wide mRNA expression studies have defined canonical signatures of T
Externí odkaz:
https://doaj.org/article/5a97d26813cd4b60ba2a11f81febd759
Autor:
Ekaterina Yurchenko, Marina T Shio, Tony C Huang, Maria Da Silva Martins, Moshe Szyf, Megan K Levings, Martin Olivier, Ciriaco A Piccirillo
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35572 (2012)
While natural CD4(+)Foxp3(+) regulatory T (nT(REG)) cells have long been viewed as a stable and distinct lineage that is committed to suppressive functions in vivo, recent evidence supporting this notion remains highly controversial. We sought to det
Externí odkaz:
https://doaj.org/article/6844e3b821fd4d9f9131b53f9ccc84bd
Autor:
Saeed Khalili, Younan Liu, Mara Kornete, Nienke Roescher, Shohta Kodama, Alan Peterson, Ciriaco A Piccirillo, Simon D Tran
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38615 (2012)
Non-obese diabetic (NOD) mice develop Sjögren's-like disease (SS-like) with loss of saliva flow and increased lymphocytic infiltrates in salivary glands (SGs). There are recent reports using multipotent mesenchymal stromal cells (MSCs) as a therapeu
Externí odkaz:
https://doaj.org/article/1db64411a3f4400789665d2ae305dd10