Proteasome Levels and Activity in Pregnancies Complicated by Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Thrombocytopenia (HELLP) Syndrome

Autor: Megan Locke, Michelle Axe, Irina A. Buhimschi, Catalin S. Buhimschi, Guomao Zhao, Kathryn Berryman

Publikováno v: Hypertension. 73:1308-1318

Excessive accumulation of misfolded proteins was recently demonstrated in preeclampsia. We examined levels and activity of circulatory proteasome and immunoproteasome (inflammatory subtype) in preeclampsia and hemolysis, elevated liver enzymes, and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::085ea7c2fbfc0de6b354acbfa1daeaf9
https://doi.org/10.1161/hypertensionaha.118.12437

Circulating 20S proteasome for assessing protein energy wasting syndrome in hemodialysis patients

Autor: Marine Freist, Elodie Gentes, Carole Philipponnet, Mohamed Hadj Abdelkader, Bruno Pereira, Aurélien Piraud, Cyril Garrouste, Anne-Elisabeth Heng, Julien Aniort

Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0236948 (2020)
PLoS ONE
PLoS ONE, 2020, 15 (7), ⟨10.1371/journal.pone.0236948⟩
PLoS ONE, Public Library of Science, 2020, 15 (7), pp.e0236948. ⟨10.1371/journal.pone.0236948⟩
PLoS ONE, 2020, 15 (7), pp.e0236948. ⟨10.1371/journal.pone.0236948⟩

International audience; Protein energy wasting (PEW) including muscle atrophy is a common complication in chronic hemodialysis patients. The ubiquitin proteasome system (UPS) is the main proteolytic system causing muscle atrophy in chronic kidney dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62f48f3a3c9561b9b698bbb94fcb5a7
https://doaj.org/article/464c4d8be4f44644afdb6e3442a1ca23

Immunoproteasome in the blood plasma of children with acute appendicitis, and its correlation with proteasome and UCHL1 measured by SPR imaging biosensors

Autor: Adam Hermanowicz, Robert Milewski, Wojciech Dębek, Ewa Gorodkiewicz, Anna Sankiewicz, Ewa Matuszczak

Publikováno v: Clinical and Experimental Immunology. 191:125-132

Summary The aim of this study was to determinate the immunoproteasome concentration in the blood plasma of children with appendicitis, and its correlation with circulating proteasome and ubiquitin carboxyl-terminal hydrolase L1 (UCHL1). Twenty-seven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acef5c02ed01c7f83301d7be7e0f0491
https://doi.org/10.1111/cei.13056

Alveolar and intraparenchymal proteasome in sarcoidosis

Autor: Francesco Bonella, K. Grunert, Jeremias Wohlschlaeger, Kurt Werner Schmid, R. Alami, Peter Bauer, Jürgen Peters, Ulrich Costabel, Burkhardt Dahlmann, Stephan Urs Sixt, J. Hakenbeck

Publikováno v: Respiratory Medicine. 108:1534-1541

Summary Background In sarcoidosis, an antigen specific immune response is a putative mechanism, resulting in granulomatous inflammation. Since the proteasome is involved in antigen presentation, alterations in the alveolar and parenchymal proteasomal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bfe339082265c16049c3deacfdbb1c4
https://doi.org/10.1016/j.rmed.2014.09.004

Immunoproteasome in the Plasma of Pediatric Patients With Moderate and Major Burns, and Its Correlation With Proteasome and UCHL1 Measured by SPR Imaging Biosensors

Autor: Adam Hermanowicz, Marta Komarowska, Anna Sankiewicz, Wojciech Dębek, Robert Milewski, Diana Markowska, Ewa Gorodkiewicz, Ewa Matuszczak, Artur Weremijewicz

Publikováno v: Journal of burn careresearch : official publication of the American Burn Association. 39(6)

The aim of this study was to determine the immunoproteasome concentration in blood plasma of pediatric patients with moderate and major burns and its correlation with circulating proteasome and ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) with su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2925ab6b58c6c8e1721e942fd7fbc3d8
https://pubmed.ncbi.nlm.nih.gov/29534191