Zobrazeno 1 - 10
of 493
pro vyhledávání: '"Circular RNA/circRNA"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Spinal muscular atrophy (SMA) genes, SMN1 and SMN2 (hereinafter referred to as SMN1/2), produce multiple circular RNAs (circRNAs), including C2A–2B–3–4 that encompasses early exons 2A, 2B, 3 and 4. C2A-2B-3-4 is a universally and abund
Externí odkaz:
https://doaj.org/article/7d6d0f64ce3f4042b7ff32505f5de059
Autor:
Xi Wu, Yuan Fang, Yunru Gu, Haoyang Shen, Yangyue Xu, Tingting Xu, Run Shi, Duo Xu, Jingxin Zhang, Kai Leng, Yongqian Shu, Pei Ma
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-17 (2024)
Abstract Gastric cancer (GC) is a common malignant tumor worldwide, especially in East Asia, with high incidence and mortality rate. Epigenetic modifications have been reported to participate in the progression of gastric cancer, among which m6A is t
Externí odkaz:
https://doaj.org/article/d63427d1461445039fd59bc2cdd30b40
Autor:
Bajin Wei, Weiyang Lou
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 1, Pp 55-65 (2024)
Sorafenib resistance is a major obstacle influencing its therapeutic efficacy in advanced hepatocellular carcinoma (HCC). The knowledge of circular RNAs (circRNAs), a group of novel endogenous non-coding RNAs, in sorafenib resistance of HCC is still
Externí odkaz:
https://doaj.org/article/99242dbe00cf45e18b8b19cba6b24d68
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 1, Pp 105-115 (2024)
Circular RNAs (circRNAs) are a special class of non-coding RNAs with the ring structure. They are stable, abundant and conservative across mammals. The biogenesis and molecular properties of circRNAs are being elucidated, which exert regulatory funct
Externí odkaz:
https://doaj.org/article/b2e5504a7996438fb8fd440ee09ae44d
Autor:
Jinbin Chen, Boqi Rao, Zeqin Huang, Chen Xie, Yonghui Yu, Binyao Yang, Di Wu, Dedong Wang, Fuman Qiu, Yifeng Zhou, Yibin Deng, Jiachun Lu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Lung cancer is the most prevalent cancer worldwide, with non-small cell lung cancer (NSCLC) accounting for 85% of all cases. Circular RNAs(circRNA) play crucial roles in regulating the progression of lung cancer. Despite the ident
Externí odkaz:
https://doaj.org/article/877810e242e145dcb317363afa1b6fe6
Autor:
FU Lirong, ZHANG Chen
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 43, Iss 11, Pp 1445-1449 (2023)
Schizophrenia is a complex and severe mental disorder, the precise cause of which remains unknown. Circular RNA (circRNA), a type of non-coding RNA with a loop-like structure, is abundant in eukaryotic cell transcriptomes. Recent advancements in mole
Externí odkaz:
https://doaj.org/article/93a6698f6404421993f7821cfea79095
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 8, Pp 934-940 (2023)
Objective(s): Huntington’s disease (HD) is identified as a progressive genetic disorder caused by a mutation in the Huntington gene. Although the pathogenesis of this disease has not been fully understood, investigations have demonstrated the role
Externí odkaz:
https://doaj.org/article/518c452015f74c1b823f9a3c6b52c039
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)
Abstract Background Hepatic encephalopathy-induced hyperammonemia alters astrocytic glutamate metabolism in the brain, which is involved in cognitive decline. To identify specific therapeutic strategies for the treatment of hepatic encephalopathy, va
Externí odkaz:
https://doaj.org/article/9a532ab30fcb4bd4a06e4fa2dc16fc58
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/4a8f5fc10f614ea7a36c10b8dc0ddeff
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Low back pain (LBP) is a major public health problem worldwide and a significant health and economic burden. Intervertebral disc degeneration (IDD) is the reason for LBP. However, we have not identified effective therapeutic strategies to address thi
Externí odkaz:
https://doaj.org/article/2a909c6a19c24f1ebcd1e89da16a5b6b