Zobrazeno 1 - 10
of 423
pro vyhledávání: '"Circadian Oscillators"'
Autor:
Laurent Perrin, Ursula Loizides-Mangold, Stéphanie Chanon, Cédric Gobet, Nicolas Hulo, Laura Isenegger, Benjamin D Weger, Eugenia Migliavacca, Aline Charpagne, James A Betts, Jean-Philippe Walhin, Iain Templeman, Keith Stokes, Dylan Thompson, Kostas Tsintzas, Maud Robert, Cedric Howald, Howard Riezman, Jerome N Feige, Leonidas G Karagounis, Jonathan D Johnston, Emmanouil T Dermitzakis, Frédéric Gachon, Etienne Lefai, Charna Dibner
Publikováno v:
eLife, Vol 7 (2018)
Circadian regulation of transcriptional processes has a broad impact on cell metabolism. Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial muscle biopsies in vivo with profiles of human skeletal myotubes synchro
Externí odkaz:
https://doaj.org/article/8ea7e67b24d542c897c0de2adf446cbc
Autor:
Leonardo Domingues de Araujo, Silvia Ruiz Roa, Ana Carolina Bueno, Fernanda Borchers Coeli-Lacchini, Clarissa Silva Martins, Ernane Torres Uchoa, Jose Antunes-Rodrigues, Lucila Leico Kagohara Elias, Paula Conde Lamparelli Elias, Ayrton Custodio Moreira, Margaret de Castro
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Food access restriction is associated to changes in gene expression of the circadian clock system. However, there are only a few studies investigating the effects of non-photic synchronizers, such as food entrainment, on the expression of clock genes
Externí odkaz:
https://doaj.org/article/c7c48a21af804eeda20a3c916742379c
Autor:
Manon Torres, Denis Becquet, Marie-Pierre Blanchard, Séverine Guillen, Bénédicte Boyer, Mathias Moreno, Jean-Louis Franc, Anne-Marie François-Bellan
Publikováno v:
eLife, Vol 5 (2016)
Paraspeckles are nuclear bodies form around the long non-coding RNA, Neat1, and RNA-binding proteins. While their role is not fully understood, they are believed to control gene expression at a post-transcriptional level by means of the nuclear reten
Externí odkaz:
https://doaj.org/article/ac7072ca62aa46eb9ed5edc842c2e0e7
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Circadian and circannual cycles trigger physiological changes whose reflection on human transcriptomes remains largely uncharted. We used the time and season of death of 932 individuals from GTEx to jointly investigate transcriptomic changes associat
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009698 (2021)
PLoS Computational Biology
PLoS Computational Biology
We propose a stochastic distributed delay model together with a Markov random field prior and a measurement model for bioluminescence-reporting to analyse spatio-temporal gene expression in intact networks of cells. The model describes the oscillatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0d2fef1150b0813b01e1b2e97f8493
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 9, p e1009790 (2021)
PLoS Genetics, Vol 17, Iss 9, p e1009790 (2021)
Recent studies have demonstrated that astrocytes cooperate with neurons of the brain to mediate circadian control of many rhythmic processes including locomotor activity and sleep. Transcriptional profiling studies have described the overall rhythmic
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1009008 (2021)
PLoS Computational Biology
PLoS Computational Biology
Modeling biochemical reactions by means of differential equations often results in systems with a large number of variables and parameters. As this might complicate the interpretation and generalization of the obtained results, it is often desirable
Autor:
Finger, Anna-Marie, Jäschke, Sebastian, del Olmo, Marta, Hurwitz, Robert, Granada, Adrián E., Herzel, Hanspeter, Kramer, Achim
Publikováno v:
Sci Adv
Science Advances
Science Advances
Paracrine TGF-β signaling is crucial to maintain robust and coherent circadian rhythms of peripheral oscillator networks.
Coupling between cell-autonomous circadian oscillators is crucial to prevent desynchronization of cellular networks and di
Coupling between cell-autonomous circadian oscillators is crucial to prevent desynchronization of cellular networks and di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e002cbbc7e80f07acbe4dd2ce067b472
https://hdl.handle.net/21.11116/0000-0009-13B7-321.11116/0000-0009-13B9-1
https://hdl.handle.net/21.11116/0000-0009-13B7-321.11116/0000-0009-13B9-1
Autor:
Priya Crosby, John S. O’Neill, Adam R. Stinchcombe, Carl Hirschie Johnson, Shu-qun Shi, Martin Sládek, Tenjin C. Shrestha, Alena Sumová, Pavel Houdek, Martin R. Ralph
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008987 (2021)
PLoS Computational Biology
PLoS Computational Biology
Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms exhibit increased bimodal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab2a79067a0660398fdaa507e7ecf5
Autor:
Courtney N. Passow, Nicolas Rohner, James B. Jaggard, Katya L. Mack, Emma Y. Roback, Johanna E. Kowalko, Estephany Ferrufino, Alex C. Keene, Suzanne E. McGaugh, Sarah E. Smith, Brian D. Slaughter, Dai Tsuchiya, Jenna L. Persons, Bethany A. Stanhope
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009642 (2021)
PLoS Genetics
PLoS Genetics
Circadian rhythms are nearly ubiquitous throughout nature, suggesting they are critical for survival in diverse environments. Organisms inhabiting largely arrhythmic environments, such as caves, offer a unique opportunity to study the evolution of ci