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Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice

Autor: Aloisi E., Le Corf K., Dupuis J., Zhang P., Ginger M., Labrousse V., Spatuzza M., Georg Haberl M., Costa L., Shigemoto R., Tappe-Theodor A., Drago F., Vincenzo Piazza P., Mulle C., Groc L., Ciranna L., Catania M.V., Frick A.

Publikováno v: Nature communications 8 (2017): 1–14. doi:10.1038/s41467-017-01191-2
info:cnr-pdr/source/autori:Aloisi E.; Le Corf K.; Dupuis J.; Zhang P.; Ginger M.; Labrousse V.; Spatuzza M.; Georg Haberl M.; Costa L.; Shigemoto R.; Tappe-Theodor A.; Drago F.; Vincenzo Piazza P.; Mulle C.; Groc L.; Ciranna L.; Catania M.V.; Frick A./titolo:Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice/doi:10.1038%2Fs41467-017-01191-2/rivista:Nature communications/anno:2017/pagina_da:1/pagina_a:14/intervallo_pagine:1–14/volume:8

Metabotropic glutamate receptor subtype 5 (mGluR5) is crucially implicated in the pathophysiology of Fragile X Syndrome (FXS); however, its dysfunction at the sub-cellular level, and related synaptic and cognitive phenotypes are unexplored. Here, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::00882e94ee9aaa3f604dc2c8403e2495
https://publications.cnr.it/doc/386745

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Dysfunctions of metabotropic glutamate receptor subtype 5 (mGlu5) receptors in a mouse model of Fragile X syndrome

Autor: Catania, M. V., Spatuzza, M., Aloisi, E., D'Antoni, S., Dupuis, J. P., Costa, LARA TANIA, Bonaccorso, C. M., Molinaro, G., Battaglia, G., Musumeci, S., Davidovic, L., Bardoni, B., Ciranna, L., Nicoletti, F., Groc, L., Frick, A.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3978::1470e82c98678a342850185db70e8e2f
http://hdl.handle.net/11570/3040173

Intracellular mechanisms responsible for serotonin-mediated reversal of metabotropic glutamate receptor-mediated long-term depression (mGluR-LTD) in wild-type and Fmr1 KO mouse hippocampus

Autor: Costa, LARA TANIA, Bonaccorso, C. M., Musumeci, S. A., Catania, M., Ciranna, L.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3978::004f728accf8a13f1b54fb69634d6e34
http://hdl.handle.net/11570/2618968