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pro vyhledávání: '"Ciprofloxacin/chemistry"'
Autor:
Benjamin D. Bax, Pan F. Chan, Michael M. Hann, Michael N. Gwynn, Daniel R. Gentry, Ceri J. Lewis, Jo J. Jones, Claus Spitzfaden, Andrew P. Fosberry, Martin Hibbs, Earl May, Kristin K. Brown, Alexandre Wohlkonig, Drake S. Eggleston, Onkar M. P. Singh, Alan Joseph Hennessy, Andrew J. Theobald, Fabrice Gorrec, Martin R. Saunders, Anthony Shillings, Emma J. Jones, Carol Shen, Neil D. Pearson, Jianzhong Huang, Ilaria Giordano
Despite the success of genomics in identifying new essential bacterial genes, there is a lack of sustainable leads in antibacterial drug discovery to address increasing multidrug resistance. Type IIA topoisomerases cleave and religate DNA to regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea159ed95a9dbead771494c8d86bdb2
https://doi.org/10.1038/nature09197
https://doi.org/10.1038/nature09197
