Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ciprian Almonte"'
Publikováno v:
Human Gene Therapy. 10:2601-2613
Cationic liposomes have provided many advantages over viral vector formulations; however, the problem of inefficient gene expression remains. This is due in part to the nuclear membrane, which limits DNA entry into the nucleus. Cytoplasmic expression
Autor:
Simon C. Watkins, Harry Solimeo, Ciprian Almonte, Tommy S. Tillman, Stefan Wölfl, Rhonda R. McCartney, Xudong Zhang, Martin C. Schmidt
Publikováno v:
Molecular and cellular biology. 19(7)
The Std1 protein modulates the expression of glucose-regulated genes, but its exact molecular role in this process is unclear. A two-hybrid screen for Std1-interacting proteins identified the hydrophilic C-terminal domains of the glucose sensors, Snf
Autor:
Radosveta Koldamova, Ciprian Almonte, John S. Lazo, Iliya Lefterov, Simon C. Watkins, Marc T. DiSabella
Publikováno v:
Biochemistry. 38(22)
Bleomycin hydrolase (BH) is a cysteine proteinase that inactivates the anticancer drug bleomycin. Yeast BH forms a homohexameric structure that resembles a 20S proteasome and binds to single-stranded RNA and DNA. We now demonstrate that human BH (hBH
Autor:
L. Wang, Leaf Huang, Yukai He, Joseph Baar, Ciprian Almonte, Michael R. Shurin, Simon C. Watkins, Vivian Wai Yan Lui
Publikováno v:
Gene therapy. 5(11)
Down-regulation of oncogene expression by antisense-based gene therapy has been extensively studied, and in some cases, therapeutic effects have been demonstrated. We have previously shown that down-regulation of HPV16 E6 and E7 gene expression inhib