Impact of Intermediate Hyperglycemia and Diabetes on Immune Dysfunction in Tuberculosis

Autor: Eckold, C, Kumar, V, Weiner, J, Alisjahbana, B, Riza, A-L, Ronacher, K, Coronel, J, Kerry-Barnard, S, Malherbe, ST, Kleynhans, L, Stanley, K, Soeroto, A, Permana, H, Imaculata, S, Apriani, L, Ugarte-Gil, C, Walzl, G, van Crevel, R, Wijmenga, C, Critchley, JA, Dockrell, HM, Haks, M, Cliff, JM, Malherbe, S, Dockrell, H, Cliff, J, Moore, D, Griffiths, U, Laurence, Y, Aarnouste, R, Netea, M, Ruesen, C, Lachmandas, E, Kaufmann, S, Beigier, M, Golinski, R, Joosten, S, Ottenhoff, T, Vrieling, F, Smith, B, van der Spuy, G, Loxton, A, Chegou, N, Bosman, M, Thiart, L, Nitu, F, Wagman, C, Editoiu, C, Tshivhula, H, Selamolela, M, Prins, N, du Plessis, W, van Rensburg, I, du Toit, L, Critchley, J, Bazavan, I, Pearson, F, Grint, D, Florescu, A, McAllister, S, Hill, P, Verrall, A, Ioana, M, Riza, A, Cioboata, R, Dudau, M, Olteanu, M, Mota, M, Popa, SG, Firanescu, A, Popa, A, Gheonea, I, Bicuti, S, Lepadat, A, Capitanescu, I, Vladu, I, Papurica, M, Clenciu, D, Bicu, M, Streba, C, Demetrian, A, Ciurea, M, Cimpoeru, A, Ciocoiu, A, Dorobantu, S, Olaru, M, Plesea, R, Popescu, EL, Valutanu, I, Cucu, M, Streata, I, Burada, F, Serban-Sosoi, S, Panduru, N, Nicoli, E, Ciontea, M, Tataru, T, Dubreu, V, Stamatoiu, L, Lopez, S, Gunawan, Y, Limascca, R, Ruslami, R, Villaizan, K, Castro, B, Flores, J, Solano, W, Soetedjo, N, Santoso, P, Dewi, N, Chaidir, L, Koesoemadinata, R, Susilawati, N, Annisa, J, Livia, R, Yunivita, V

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 72, 1, pp. 69-78
Clinical Infectious Diseases
Clinical Infectious Diseases, 72, 69-78

Background People with diabetes have an increased risk of developing active tuberculosis (TB) and are more likely to have poor TB-treatment outcomes, which may impact on control of TB as the prevalence of diabetes is increasing worldwide. Blood trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdee32a58430ee12a6a0380fc065b493
https://doi.org/10.1093/cid/ciaa751

The CARD9 Polymorphisms rs4077515, rs10870077 and rs10781499 Are Uncoupled from Susceptibility to and Severity of Pulmonary Tuberculosis

Autor: Streata, I., Weiner, J., Iannaconne, M., McEwen, G., Ciontea, M., Olaru, M., Capparelli, R., Ioana, M., Kaufmann, S., Dorhoi, A.

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0163662 (2016)
PLoS ONE
PLoS One

Genetic variants in the CARD9 gene predispose to inflammatory disorders and chronic infectious diseases. Tuberculosis (TB), a chronic infectious disease affecting the lung, is lethal in Card9-deficient mice. We hypothesized that polymorphisms in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0c792a89ddb1f609ff1c12f01fde695f
http://europepmc.org/articles/PMC5042433?pdf=render

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