Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cinzia Imberti"'
Autor:
Afnan M. F. Darwesh, Cinzia Imberti, Joanna J. Bartnicka, Fahad Al-Salemee, Julia E. Blower, Alex Rigby, Jayanta Bordoloi, Alex Griffiths, Michelle T. Ma, Philip J. Blower
Publikováno v:
Molecules, Vol 28, Iss 20, p 7217 (2023)
KP46 (tris(hydroxyquinolinato)gallium(III)) is an experimental, orally administered anticancer drug. Its absorption, delivery to tumours, and mode of action are poorly understood. We aimed to gain insight into these issues using gallium-67 and galliu
Externí odkaz:
https://doaj.org/article/781d2e5334fb4f919bb9b6a45b0024d7
Publikováno v:
Nucl Med Biol
In oncology, the holy grail of radiotherapy is specific radiation dose deposition in tumours with minimal healthy tissue toxicity. If used appropriately, injectable, systemic radionuclide therapies could meet these criteria, even for treatment of mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc7a62bc64ad3fbfd00773c69d99ffe
https://doi.org/10.1016/j.nucmedbio.2021.03.010
https://doi.org/10.1016/j.nucmedbio.2021.03.010
Autor:
Clément Soulié, Jana Kasparkova, Cinzia Imberti, Viktor Brabec, Guy J. Clarkson, Huayun Shi, Martin J. Paterson, Olga Novakova, Peter J. Sadler
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Photoactivatable agents offer the prospect of highly selective cancer therapy with low side effects and novel mechanisms of action that can combat current drug resistance. 1,8‐Naphthalimides with their extended π system can behave as light‐harve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae051cb26733f6a5f897f8f7bb9b80a
http://europepmc.org/articles/PMC8361943
http://europepmc.org/articles/PMC8361943
Publikováno v:
Chemical Communications (Cambridge, England)
The novel Pt(iv) complex trans,trans-[Pt(N3)2(Py)2(OH)(OCO-(PEG)2-NHCSNH-Ph-NCS)] (Pt4) conjugates to the side chain of lysine amino acids in proteins under mild conditions. Reaction with myoglobin generated a bioconjugate that was stable in the dark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bad7fa1d45be1d53efa3be2f4ff66c2
https://doi.org/10.1039/d1cc02722k
https://doi.org/10.1039/d1cc02722k
Autor:
Xianjin Cui, Vicky Goh, Rafael Torres Martin de Rosales, Lea Ann Dailey, Jaclyn L Lange, Cinzia Imberti, Thais Fedatto Abelha, Yong Yan, Istvan Szanda
Publikováno v:
Journal of Materials Chemistry. B
Computed tomography (CT) is one of the most widespread imaging techniques in clinical use worldwide. CT contrast agents are administered to improve soft tissue contrast and highlight blood vessels. However, the range of CT contrast agents available i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc45eece278e1e087e14599649d7ca7
https://doi.org/10.1039/d0tb00969e
https://doi.org/10.1039/d0tb00969e
Autor:
Elizabeth J Anthony, Edward C Lant, Elizabeth M. Bolitho, Huayun Shi, Jane M. Donnelly, Wen-Ying Zhang, Cinzia Imberti, Marta Palau, Peter J. Sadler, Russell J. Needham, Fang-Xin Wang, Oliver W. L. Carter, Hannah E. Bridgewater, Zijin Zhang, Frederik Lermyte
Publikováno v:
Chemical Science
Metals play vital roles in nutrients and medicines and provide chemical functionalities that are not accessible to purely organic compounds. At least 10 metals are essential for human life and about 46 other non-essential metals (including radionucli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d7d048aed2720f8b5a75ffd554dfa7
https://doi.org/10.1039/d0sc04082g
https://doi.org/10.1039/d0sc04082g
Autor:
Alexandra Sink, Samya Banerjee, Juliusz A. Wolny, Cinzia Imberti, Edward C. Lant, Marc Walker, Volker Schünemann, Peter J. Sadler
We have studied activation of the methyl C–H bonds in the cyclopentadienyl ligands of half-sandwich Rh(III) complexes [η5-CpXRh(N,N′)Cl]+ by observing the dependence of sequential H/D exchange on variations in CpX = Cp* (complexes 1 and 2), Me4P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f772f829614edff19bbb4d6e790ccc
http://wrap.warwick.ac.uk/169182/1/WRAP-Kinetics-and-mechanism-of-sequential-ring-methyl-C-H-activation-in-cyclopentadienyl-rhodiumiii-complexes-Sadler-2022.pdf
http://wrap.warwick.ac.uk/169182/1/WRAP-Kinetics-and-mechanism-of-sequential-ring-methyl-C-H-activation-in-cyclopentadienyl-rhodiumiii-complexes-Sadler-2022.pdf
Autor:
Cinzia Imberti, Paul D. Quinn, Elizabeth M. Bolitho, Huayun Shi, Carlos Sanchez-Cano, Peter J. Sadler, Maria Harkiolaki
Publikováno v:
Journal of the American Chemical Society
The Pt(IV) prodrug trans, trans, trans-[Pt(pyridine)2(N3)2(OH)2] (Pt1) and its coumarin derivative trans, trans, trans-[Pt(pyridine)2(N3)2(OH)(coumarin-3-carboxylate)] (Pt2) are promising agents for photoactivated chemotherapy. These complexes are in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bb352f92e0ceeec02013fdaa7bcc5f
https://pubmed.ncbi.nlm.nih.gov/34808054
https://pubmed.ncbi.nlm.nih.gov/34808054
Publikováno v:
Inorganic chemistry frontiers
Mono-axial functionalised octahedral diazido Pt(iv) complexes trans, trans, trans-[Pt(py)2(N3)2(OR1)(OR2)] (OR1 = OH and OR2 = anticancer agent coumarin-3 carboxylate (cou, 2a), pyruvate dehydrogenase kinase (PDK) inhibitors 4-phenylbutyrate (PhB, 2b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41187864cce5a9af0b8e13609e32b21
https://pubmed.ncbi.nlm.nih.gov/33786191
https://pubmed.ncbi.nlm.nih.gov/33786191
Autor:
Samya Banerjee, Mu Sheng Zeng, Cinzia Imberti, Guy J. Clarkson, Isolda Romero-Canelón, Qian Wang, Lawrence S. Young, Qian Zhong, Abraha Habtemariam, Wen-Ying Zhang, Peter J. Sadler
Publikováno v:
Inorganica chimica acta
We report the synthesis and characterization of novel pentamethylcyclopentadienyl (Cp*) iridium(III) complexes [(Cp*)Ir(4-methyl-4′-carboxy-2,2′-bipyridine)Cl]PF6 (Ir-I), the product (Ir-II) from amide coupling of Ir-I to dibenzocyclooctyne-amine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dde5a37ebadfd2f6b6e49891b55ec6c
https://pubmed.ncbi.nlm.nih.gov/33776131
https://pubmed.ncbi.nlm.nih.gov/33776131