Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Cinzia Dello Russo"'
Autor:
Cinzia Dello Russo, Natalia Cappoli, Elisabetta Tabolacci, Liliana Sollazzi, Pierluigi Navarra, Paola Aceto
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 295-309 (2023)
Remifentanil is a potent ultra-short acting μ-opioid analgesic drug, frequently used in anaesthesia due to its favorable pharmacodynamic and pharmacokinetic profile. It may be associated with the occurrence of hyperalgesia. Preclinical studies sugge
Externí odkaz:
https://doaj.org/article/9e67f52793c34d66bbea81e20a749645
Autor:
Filippo Del Tedesco, Flaminio Sessa, Rikardo Xhemalaj, Liliana Sollazzi, Cinzia Dello Russo, Paola Aceto
Publikováno v:
Saudi Journal of Anaesthesia, Vol 17, Iss 4, Pp 491-499 (2023)
The administration of analgesic drugs in elderly patients should take into account age-related physiological changes, loss of efficiency of homeostatic mechanisms, and pharmacological interactions with chronic therapies. Underestimation of pain in pa
Externí odkaz:
https://doaj.org/article/9dd2cbe4be4648428ed360895d26c7b4
Autor:
Evelien G. E. Hurkmans, Marije J. Klumpers, Cinzia Dello Russo, Ward De Witte, Henk-Jan Guchelaar, Hans Gelderblom, Anne-Marie Cleton-Jansen, Sita H. Vermeulen, Suzanne Kaal, Winette T. A. van der Graaf, Uta Flucke, Corrie E. M. Gidding, Hendrik W. B. Schreuder, Eveline S. J. M. de Bont, Huib N. Caron, Giovanna Gattuso, Elisabetta Schiavello, Monica Terenziani, Maura Massimino, Geoff McCowage, Sumanth Nagabushan, Anuja Limaye, Victoria Rose, Daniel Catchpoole, Andrea L. Jorgensen, Christopher Barton, Lucy Delaney, Daniel B. Hawcutt, Munir Pirmohamed, Barry Pizer, Marieke J. H. Coenen, D. Maroeska W. M. te Loo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Hearing loss (ototoxicity) is a major adverse effect of cisplatin and carboplatin chemotherapy. The aim of this study is to identify novel genetic variants that play a role in platinum-induced ototoxicity. Therefore, a genome-wide association study w
Externí odkaz:
https://doaj.org/article/a8f79afc4fc54f8c9b487d722feb88e0
Autor:
Cinzia Dello Russo, Pierluigi Navarra
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Several drugs gained market authorization based on the demonstration of improved progression-free survival (PFS), adopted as a primary endpoint in Phase 3 clinical trials. In addition, an increasing number of drugs have been granted accelerated appro
Externí odkaz:
https://doaj.org/article/b29f14ce19ca4aa897a4e33ca8f7ecbb
Autor:
Elizabeth Pavez Loriè, Sarah Baatout, Alexander Choukér, Judith-Irina Buchheim, Bjorn Baselet, Cinzia Dello Russo, Virginia Wotring, Monica Monici, Lucia Morbidelli, Dimitri Gagliardi, Julia Caroline Stingl, Leonardo Surdo, Vincent Lai Ming Yip
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The aim of personalized medicine is to detach from a “one-size fits all approach” and improve patient health by individualization to achieve the best outcomes in disease prevention, diagnosis and treatment. Technological advances in sequencing, i
Externí odkaz:
https://doaj.org/article/5e238869eb3c49ee86ed9d861b21df3a
Autor:
Irene L. Gutiérrez, Cinzia Dello Russo, Fabiana Novellino, Javier R. Caso, Borja García-Bueno, Juan C. Leza, José L. M. Madrigal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6143 (2022)
A growing body of evidence demonstrates the important role of the noradrenergic system in the pathogenesis of many neurodegenerative processes, especially Alzheimer’s disease, due to its ability to control glial activation and chemokine production
Externí odkaz:
https://doaj.org/article/ad8b2b9266f84f0ab5f2e009fa7273d4
Autor:
Cinzia Dello Russo, Natalia Cappoli, Isabella Coletta, Daniele Mezzogori, Fabiola Paciello, Giacomo Pozzoli, Pierluigi Navarra, Alessandra Battaglia
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-24 (2018)
Abstract Microglia, unique myeloid cells residing in the brain parenchyma, represent the first line of immune defense within the central nervous system. In addition to their immune functions, microglial cells play an important role in other cerebral
Externí odkaz:
https://doaj.org/article/ee1d14ed8d0c4077ad7cec42bd40abc7
Publikováno v:
ASN Neuro, Vol 6 (2014)
Malignant gliomas are primary brain tumors characterized by morphological and genetic complexities, as well as diffuse infiltration into normal brain parenchyma. Within gliomas, microglia/macrophages represent the largest tumor-infiltrating cell popu
Externí odkaz:
https://doaj.org/article/56fd21a07e8748b5bbb3b291e6732a84
Autor:
Lucia Lisi, Giovanni Camardese, Mariangela Treglia, Giuseppe Tringali, Cinzia Carrozza, Luigi Janiri, Cinzia Dello Russo, Pierluigi Navarra
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52585 (2013)
It is now well established that major depression is accompanied and characterized by altered responses of the immune-inflammatory system. In this study we investigated the pro-inflammatory activation of monocytes isolated from depressed patients as a
Externí odkaz:
https://doaj.org/article/d53d7bca35a247e3abce8f9a915ab9d1
Autor:
Shao Xia Lin, Lucia Lisi, Cinzia Dello Russo, Paul E Polak, Anthony Sharp, Guy Weinberg, Sergey Kalinin, Douglas L Feinstein
Publikováno v:
ASN Neuro, Vol 3 (2011)
DMF (dimethyl fumarate) exerts anti-inflammatory and prometabolic effects in a variety of cell types, and a formulation (BG-12) is being evaluated for monotherapy in multiple sclerosis patients. DMF modifies glutathione (GSH) levels that can induce e
Externí odkaz:
https://doaj.org/article/60cddea7fed64cdb8862865866aa3fdc