Transmembrane Protein TMEM230, a Target of Glioblastoma Therapy

Autor: Cinzia Cocola, Valerio Magnaghi, Edoardo Abeni, Paride Pelucchi, Valentina Martino, Laura Vilardo, Eleonora Piscitelli, Arianna Consiglio, Giorgio Grillo, Ettore Mosca, Roberta Gualtierotti, Daniela Mazzaccaro, Gina La Sala, Chiara Di Pietro, Mira Palizban, Sabino Liuni, Giuseppina DePedro, Stefano Morara, Giovanni Nano, James Kehler, Burkhard Greve, Alessio Noghero, Daniela Marazziti, Federico Bussolino, Gianfranco Bellipanni, Igea D’Agnano, Martin Götte, Ileana Zucchi, Rolland Reinbold

Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Glioblastomas (GBM) are the most aggressive tumors originating in the brain. Histopathologic features include circuitous, disorganized, and highly permeable blood vessels with intermittent blood flow. These features contribute to the inability to dir

Externí odkaz: https://doaj.org/article/75f0ce9fbf4943ef8b3abd80f17950d9

The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties

Autor: Felipe C. O. B. Teixeira, Archana Vijaya Kumar, Sampath Kumar Katakam, Cinzia Cocola, Paride Pelucchi, Monika Graf, Ludwig Kiesel, Rolland Reinbold, Mauro S. G. Pavão, Burkhard Greve, Martin Götte

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Heparan sulfate (HS) is a glycosaminoglycan found mainly in its protein-conjugated form at the cell surface and the extracellular matrix. Its high sulfation degree mediates functional interactions with positively charged amino acids in proteins. 2-O

Externí odkaz: https://doaj.org/article/670d6cb63448476f98ff5f095c288aa4

scMuffin: an R package for resolving solid tumor heterogeneity from single-cell expression data

Autor: Valentina Nale, Noemi Di Nanni, Alice Chiodi, Ingrid Cifola, Marco Moscatelli, Cinzia Cocola, Matteo Gnocchi, Eleonora Piscitelli, Rolland Reinbold, Ileana Zucchi, Luciano Milanesi, Alessandra Mezzelani, Paride Pelucchi, Ettore Mosca

INTRODUCTIONSingle-cell (SC) gene expression analysis is crucial to dissect the complex cellular heterogeneity of solid tumors, which is one of the main obstacles for the development of effective cancer treatments. Such tumors typically contain a mix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3539699260bdde91e39ffd6ed98028c3
https://doi.org/10.1101/2022.06.01.494129

Integrating microstructured electrospun scaffolds in an open microfluidic system for in vitro studies of human patient-derived primary cells

Autor: Valentina Cirillo, Diego Repetto, Ioannis Missitzis, Luigi Ambrosio, Giovanni Bertalot, Denise Pezzuoli, Ugo Valbusa, Rolland Reinbold, Valentina Martino, Angelos D. Gritzapis, Gianfranco Bellipanni, Marica Marrese, Patrizia Guida, Paride Pelucchi, Martin Götte, Giuseppe Firpo, Vincenzo Guarino, Elena Angeli, Theodoros Karnavas, Giovanni Porta, Luca Repetto, Marietta D’Albore, Cinzia Cocola, Ileana Zucchi, Eleonora Piscitelli

Publikováno v: ACS biomaterials science & engineering 6 (2020): 3649–3663. doi:10.1021/acsbiomaterials.0c00352
info:cnr-pdr/source/autori:Guida P.; Piscitelli E.; Marrese M.; Martino V.; Cirillo V.; Guarino V.; Angeli E.; Cocola C.; Pelucchi P.; Repetto L.; Firpo G.; Karnavas T.; Gotte M.; Gritzapis A.; D'Albore M.; Repetto D.; Pezzuoli D.; Missitzis I.; Porta G.; Bertalot G.; Bellipanni G.; Zucchi I.; Ambrosio L.; Valbusa U.; Reinbold R.A./titolo:Integrating microstructured electrospun scaffolds in an open microfluidic system for in vitro studies of human patient-derived primary cells/doi:10.1021%2Facsbiomaterials.0c00352/rivista:ACS biomaterials science & engineering/anno:2020/pagina_da:3649/pagina_a:3663/intervallo_pagine:3649–3663/volume:6

Recent studies have suggested that microenvironmental stimuli play a significant role in regulating cellular proliferation and migration, as well as in modulating self-renewal and differentiation processes of mammary cells with stem cell (SCs) proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0080112bb76d3d035f37dc14ee7787e
http://hdl.handle.net/11383/2131583

FGF2 and EGF Are Required for Self-Renewal and Organoid Formation of Canine Normal and Tumor Breast Stem Cells

Autor: Cinzia, Cocola, Stefano, Molgora, Eleonora, Piscitelli, Maria Cristina, Veronesi, Marianna, Greco, Cinzia, Bragato, Monica, Moro, Mariacristina, Crosti, Brian, Gray, Luciano, Milanesi, Valeria, Grieco, Gaia Cecilia, Luvoni, James, Kehler, Gianfranco, Bellipanni, Rolland, Reinbold, Ileana, Zucchi, Antonio, Giordano

Publikováno v: Journal of cellular biochemistry
118 (2017): 570–584. doi:10.1002/jcb.25737
info:cnr-pdr/source/autori:Cocola, Cinzia; Molgora, Stefano; Piscitelli, Eleonora; Veronesi, Maria Cristina; Greco, Marianna; Bragato, Cinzia; Moro, Monica; Crosti, Mariacristina; Gray, Brian; Milanesi, Luciano; Grieco, Valeria; Luvoni, Gaia Cecilia; Kehler, James; Bellipanni, Gianfranco; Reinbold, Rolland; Zucchi, Ileana; Giordano, Antonio/titolo:FGF2 and EGF Are Required for Self-Renewal and Organoid Formation of Canine Normal and Tumor Breast Stem Cells/doi:10.1002%2Fjcb.25737/rivista:Journal of cellular biochemistry (Print)/anno:2017/pagina_da:570/pagina_a:584/intervallo_pagine:570–584/volume:118

Recent studies suggest that human tumors are generated from cancer cells with stem cell (SC) properties. Spontaneously occurring cancers in dogs contain a diversity of cells that like for human tumors suggest that certain canine tumors are also gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::212c5d0e11f5176fe12038e62e37eff9
http://hdl.handle.net/11365/1006990