Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Cinzia, Bizzarri"'
Publikováno v:
Mediterranean Journal of Social Sciences, Vol 9, Iss 1 (2018)
Our empirical study aims at understanding and analyzing whether and how the way in which the “sons of Mafia” consider their own family and the society in general has changed over time. The psychological study is based on a sample of 11 subjects a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d193f6b6c565920ba01cf87ad59efe34
http://www.richtmann.org/journal/index.php/mjss/article/view/10153
http://www.richtmann.org/journal/index.php/mjss/article/view/10153
Autor:
Mauro M. Teixeira, Juan Carlos Cutrin, Riccardo Bertini, Emanuela Galliera, Giuseppe Nano, Maria Candida Cesta, B Cavalieri, C. Di Giacinto, P. Di Benedetto, Marcello Allegretti, Andrea R. Beccari, Remo Castro Russo, Andrea Aramini, Lucíola S. Barcelos, Massimo Locati, Isabelle Gloaguen, Alessio Moriconi, Massimiliano M. Corsi, Silvia Passos Andrade, Cinzia Bizzarri
Publikováno v:
British Journal of Pharmacology. 165:436-454
BACKGROUND AND PURPOSE DF 2156A is a new dual inhibitor of IL-8 receptors CXCR1 and CXCR2 with an optimal pharmacokinetic profile. We characterized its binding mode, molecular mechanism of action and selectivity, and evaluated its therapeutic potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49490486cd39d0ddd9d5359b2a037a1
https://doi.org/10.1111/j.1476-5381.2011.01566.x
https://doi.org/10.1111/j.1476-5381.2011.01566.x
Autor:
Massimo Locati, Riccardo Bertini, Alberto Mantovani, Cinzia Bizzarri, Marcello Allegretti, Andrea R. Beccari
Publikováno v:
Trends in Pharmacological Sciences. 29:280-286
Given the central role of chemokines in infection, inflammation and immunity, chemokine receptors are a prime target for pharmacological intervention, and more so after the recent approval of chemokine receptor inhibitors for HIV. Allosteric inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba6f4703771f8c14fbce0d0fa773f51
https://doi.org/10.1016/j.tips.2008.03.005
https://doi.org/10.1016/j.tips.2008.03.005
Autor:
Marcello Allegretti, Riccardo Bertini, Cinzia Bizzarri, Mauro M. Teixeira, F Cattani, Fernando Q. Cunha, Wagner Luiz Tafuri, F Policani, Stephen Poole, Michele M. Barsante, Thiago M. Cunha
Publikováno v:
British Journal of Pharmacology. 153:992-1002
Background and purpose: Chemokine receptors CXCR1 and CXCR2 may mediate influx of neutrophils in models of acute and chronic inflammation. The potential benefits of oral administration of a CXCR1/2 inhibitor, DF 2162, in adjuvant-induced polyarthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::996e9b71c23a0e586234944bab5d0a4a
https://doi.org/10.1038/sj.bjp.0707462
https://doi.org/10.1038/sj.bjp.0707462
Autor:
Paolo Vigilante, Maria Neve Cervellera, Andrea Aramini, Silvia Coniglio, Andrea R. Beccari, Sandro Colagioia, Marcello Allegretti, Alessio Moriconi, Paola Di Benedetto, Riccardo Bertini, Michela Rita Cavicchia, Maria Candida Cesta, Emanuela Galliera, Massimo Locati, Cinzia Bizzarri
Publikováno v:
Journal of Medicinal Chemistry. 50:3984-4002
Chemokines CXCL8 and CXCL1 play a key role in the recruitment of neutrophils at the site of inflammation. CXCL8 binds two membrane receptors, CXCR1 and CXCR2, whereas CXCL1 is a selective agonist for CXCR2. In the past decade, the physiopathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e498d1aa840ee02ed2aebf4a48a1728
https://doi.org/10.1021/jm061469t
https://doi.org/10.1021/jm061469t
Autor:
Cinzia Bizzarri, Marcello Allegretti, Simona Giorgini, Michela Rita Cavicchia, Andrea R. Beccari, Riccardo Bertini
Publikováno v:
Pharmacology & Therapeutics. 112:139-149
ELR+ CXC chemokines, by direct interaction with their cell surface receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are believed to be crucially involved in the direct migration and activation of leukocytes. ELR+ CXC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762fc9f22aa7cec3dbd3b8277c80d0ed
https://doi.org/10.1016/j.pharmthera.2006.04.002
https://doi.org/10.1016/j.pharmthera.2006.04.002
Autor:
Pietro Ghezzi, Cinzia Bizzarri, Francesco Colotta, Riccardo Bertini, Klas Pekkari, Geng Chang, Arne Holmgren
Publikováno v:
Antioxidants & Redox Signaling. 7:1189-1194
Thioredoxin (Trx) is a protein disulfide oxidoreductase that can be secreted and act as a chemoattractant for leukocytes. Like chemokines, it causes desensitization of monocytes against its chemotactic activity and that of monocyte chemoattractant pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3338ae341defab11dc99cd743921cff
https://doi.org/10.1089/ars.2005.7.1189
https://doi.org/10.1089/ars.2005.7.1189
Autor:
Francesco Colotta, Rosa Di Bitondo, Riccardo Bertini, Maria Candida Cesta, Piercarlo Fantucci, Nicoletta Di Bello, Valerio Berdini, Nicolini Luca, Marcello Allegretti, S. Florio, Giuseppe Nano, Vito Di Cioccio, Alessandra Topai, Massimo Locati, Vincenzo Russo, Cinzia Bizzarri, Emanuela Galliera, Giuseppe Zampella
Publikováno v:
Journal of Medicinal Chemistry. 48:4312-4331
The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs by binding the seven-transmembrane (7-TM) G-protein-coupled receptors CXC chemokine recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d6844b6304ced8be7d334c7739e673
https://doi.org/10.1021/jm049082i
https://doi.org/10.1021/jm049082i
Autor:
Francesco Colotta, Claudio Festuccia, Andrea Bianchini, B Cavalieri, Isabelle Gloaguen, Elisabetta Ferretti, Maria Neve Cervellera, Cinzia Bizzarri, Raffaele Strippoli, Fabrizio Mainiero, Federica Casilli, Riccardo Bertini, Edoardo Alesse, Rosa Di Bitondo, Leda Biordi
Publikováno v:
Biochemical Pharmacology. 69:385-394
Repertaxin is a new non-competitive allosteric blocker of interleukin-8 (CXCL8/IL-8) receptors (CXCR1/R2), which by locking CXCR1/R2 in an inactive conformation prevents receptor signaling and human polymorphonuclear leukocyte (PMN) chemotaxis. Given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649d05945f52c7a264b6157f7eef4527
https://doi.org/10.1016/j.bcp.2004.10.007
https://doi.org/10.1016/j.bcp.2004.10.007
Autor:
Giulia Troiani, Francesco Colotta, Vito Di Cioccio, Elisa Margherita Cattozzo, Isabelle Gloaguen, Fabrizio Mainiero, Riccardo Bertini, Maria Neve Cervellera, Raffaele Strippoli, Sabrina Pagliei, Cinzia Bizzarri, Angela Santoni, Antonella Colagrande
Publikováno v:
Immunology. 111:407-415
The signalling pathways leading to CXCL8/IL-8-induced human neutrophil migration have not been fully characterized. The present study demonstrates that CXCL8 induces tyrosine phosphorylation as well as enzymatic activity of proline-rich tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b998142da8e84cf35f3be01c50e8020a
https://doi.org/10.1111/j.1365-2567.2004.01822.x
https://doi.org/10.1111/j.1365-2567.2004.01822.x