Polymorphisms in MDM2 and TP53 Genes and Risk of Developing Therapy-Related Myeloid Neoplasms

Autor: Gemma Armengol, Santiago Ramón y Cajal, María Rosa Caballín, Joan Francesc Barquinero, L. Garcia-Quevedo, Cintia Alonso, Margarita Ortega, Adoración Blanco, Yolanda Álvarez, Marta Manubens, Maria Cabezas

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

One of the most severe complications after successful cancer therapy is the development of therapy-related myeloid neoplasms (t-MN). Constitutional genetic variation is likely to impact on t-MN risk. We aimed to evaluate if polymorphisms in the p53 p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f51ad406e3fb9c8b45df9909546cfc
http://link.springer.com/article/10.1038/s41598-018-36931-x