Výsledky vyhledávání - "Cingolati, M"

A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl l-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection

Autor: Youle, M, Osio, M, Cassetti, I, Bologna, R, Zala, C, Losso, M, Lourtau, Defanti, Ca, Causarano, Ir, Di Palma, F, Landonio, S, Muscia, F, Scarpini, E, De Riz, M, Porazzi, D, La Spina, I, Ubiali, E, Foresti, C, Pastore, G, Maggi, P, Colomba, A, Fundarò, S, Pizzigallo, E, D'Alessandro, M, Dini, M, Cingolati, M, Di Gregorio, P, Bollo, M, Patti, Francesco, Pantò, G, Calvani, M, Iannuccelli, M, Levy, I, Burke, M, Werner, B, Portegies, P, Weber, J, Sharma, R, Wilkins, E, Bonnington, A, Johnson, M, Sabin, C.

Background Nucleoside reverse transcriptase inhibitors (NRTIs) disrupt neuronal mitochondrial DNA synthesis, resulting in antiretroviral toxic neuropathy (ATN). Acetyl-l-carnitine (ALCAR) enhances neurotrophic support of sensory neurones, potentially

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