Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cindy-ann Tompkins"'
Autor:
Mark H. Moss, Njira L. Lugogo, Mario Castro, Nicola A. Hanania, Andrea Ludwig-Sengpiel, Dinesh Saralaya, Rafal Dobek, Iñigo Ojanguren, Ivan Vyshnyvetskyy, Jean-Marie Bruey, Robin Osterhout, Cindy-ann Tompkins, Karen Dittrich, Kartik Raghupathi, Hector Ortega
Publikováno v:
Scientia
Asthma; Asthma worsening; Eosinophilic asthma Asma; Empitjorament de l'asma; Asma eosinofílica Asma; Empeoramiento del asma; Asma eosinofílica Background Prostaglandin D2 receptor 2 (DP2) antagonists inhibit prostaglandin D2-induced effects, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cb6aa1f9e35d8b8f1d34f6669cbfc1
https://doi.org/10.1016/j.chest.2022.02.038
https://doi.org/10.1016/j.chest.2022.02.038
Autor:
Mark H, Moss, Njira L, Lugogo, Mario, Castro, Nicola A, Hanania, Andrea, Ludwig-Sengpiel, Dinesh, Saralaya, Rafal, Dobek, Iñigo, Ojanguren, Ivan, Vyshnyvetskyy, Jean-Marie, Bruey, Robin, Osterhout, Cindy-Ann, Tompkins, Karen, Dittrich, Kartik, Raghupathi, Hector, Ortega
Publikováno v:
Chest. 162(2)
Prostaglandin DWhat is the effect of the DPIn this phase IIb, randomized, double-blind, placebo-controlled, dose-ranging, parallel-group, multicenter study, GB001 or placebo was added to standard-of-care treatment in patients with moderate to severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08a30a457306a46e34ea0b7ad0895bf2
https://pubmed.ncbi.nlm.nih.gov/35248549
https://pubmed.ncbi.nlm.nih.gov/35248549
Autor:
Karen Dittrich, Dave Singh, Mary Fitzgerald, Caroline Pattwell, Hector Ortega, Jinshan Shen, Kartik Raghupathi, Cindy-ann Tompkins
Publikováno v:
Clinical and Experimental Allergy
Background GB001 is an oral antagonist of the prostaglandin D2 receptor that may inhibit recruitment and activation of airway eosinophils, reducing airway inflammation. Objective To assess GB001 safety, efficacy and pharmacokinetics from a Phase 2 st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae2b0aaf986d0bcbca874134eb577d3
https://doi.org/10.1111/cea.13524
https://doi.org/10.1111/cea.13524
Publikováno v:
Clinical Pharmacology in Drug Development
Ozanimod (RPC1063) is an oral selective modulator of the sphingosine‐1‐phosphate 1 and 5 receptors under development for the treatment of relapsing multiple sclerosis and inflammatory bowel disease. The effects of high‐fat and low‐fat meals o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402e8284126308f6953f06ef6e4af091
http://europepmc.org/articles/PMC6099448
http://europepmc.org/articles/PMC6099448
Autor:
Cindy-ann Tompkins, Nicola A. Hanania, Koichiro Asano, Gregory J. Opiteck, Ian D. Pavord, Karen Dittrich, Masumi Hirata, Harry Southworth, Hector Ortega
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:AB20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c481c3e095d6f44ab1cb20c379314a
https://doi.org/10.1016/j.jaci.2019.12.789
https://doi.org/10.1016/j.jaci.2019.12.789
Autor:
Paul A. Frohna, Caiyan Li, Alex Straumann, Margaret H. Collins, Michael Grimm, Richard Aranda, Marc E. Rothenberg, Sandeep K. Gupta, Ikuo Hirano, Sheila Gujrathi, Larry Evans, Amy Woo, Cindy-ann Tompkins, Allan Olson, Ekaterina Safroneeva, Gregory J. Opiteck, Yehudith Assouline-Dayan, Heather Smith, Evan S. Dellon, Robert Peach, Darryl Penenberg, Alain M. Schoepfer
Publikováno v:
Gastroenterology, vol. 156, no. 3, pp. 592-603.e10
Hirano, Ikuo; Collins, Margaret H; Assouline-Dayan, Yehudith; Evans, Larry; Gupta, Sandeep; Schoepfer, Alain M; Straumann, Alex; Safroneeva, Ekaterina; Grimm, Michael; Smith, Heather; Tompkins, Cindy-Ann; Woo, Amy; Peach, Robert; Frohna, Paul; Gujrathi, Sheila; Penenberg, Darryl N; Li, Caiyan; Opiteck, Gregory J; Olson, Allan; Aranda, Richard; ... (2019). RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis. Gastroenterology, 156(3), 592-603.e10. Elsevier 10.1053/j.gastro.2018.10.051
Hirano, Ikuo; Collins, Margaret H; Assouline-Dayan, Yehudith; Evans, Larry; Gupta, Sandeep; Schoepfer, Alain M; Straumann, Alex; Safroneeva, Ekaterina; Grimm, Michael; Smith, Heather; Tompkins, Cindy-Ann; Woo, Amy; Peach, Robert; Frohna, Paul; Gujrathi, Sheila; Penenberg, Darryl N; Li, Caiyan; Opiteck, Gregory J; Olson, Allan; Aranda, Richard; ... (2019). RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis. Gastroenterology, 156(3), 592-603.e10. Elsevier 10.1053/j.gastro.2018.10.051
Eosinophilic esophagitis (EoE) is a chronic, esophageal, type 2 inflammatory response associated with increased serum levels of interleukin 13 (IL13), which might contribute to its pathogenesis. RPC4046, a recombinant humanized monoclonal antibody ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34744c32abf6a08d12672c5e607d0b0
https://pubmed.ncbi.nlm.nih.gov/30641052
https://pubmed.ncbi.nlm.nih.gov/30641052