Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cindy van Roomen"'
Autor:
Bram W. van Os, Pascal J. H. Kusters, Myrthe den Toom, Linda Beckers, Claudia M. van Tiel, Winnie G. Vos, Elize de Jong, Arnd Kieser, Cindy van Roomen, Christoph J. Binder, Myrthe E. Reiche, Menno P. de Winther, Laura A. Bosmans, Esther Lutgens
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundAtherosclerosis is the underlying cause of many cardiovascular diseases, such as myocardial infarction or stroke. B cells, and their production of pro- and anti-atherogenic antibodies, play an important role in atherosclerosis. In B cells,
Externí odkaz:
https://doaj.org/article/b457cc8d45844f5ca3e8e23782d56612
Autor:
Tanit L Gabriel, Mina Mirzaian, Berend Hooibrink, Roelof Ottenhoff, Cindy van Roomen, Johannes M F G Aerts, Marco van Eijk
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182075 (2017)
During obesity, adipose tissue macrophages (ATM) are increased in concert with local inflammation and insulin resistance. Since the levels of sphingolipid (SLs) in adipose tissue (AT) are altered during obesity we investigated the potential impact of
Externí odkaz:
https://doaj.org/article/b9f9d19f5ca1454db0869eee354abebd
Autor:
Daniela Herrera Moro Chao, Wouter W Kallemeijn, Andre R A Marques, Marie Orre, Roelof Ottenhoff, Cindy van Roomen, Ewout Foppen, Maria C Renner, Martina Moeton, Marco van Eijk, Rolf G Boot, Willem Kamphuis, Elly M Hol, Jan Aten, Hermen S Overkleeft, Andries Kalsbeek, Johannes M F G Aerts
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138107 (2015)
Gaucher disease is characterized by lysosomal accumulation of glucosylceramide due to deficient activity of lysosomal glucocerebrosidase (GBA). In cells, glucosylceramide is also degraded outside lysosomes by the enzyme glucosylceramidase 2 (GBA2) of
Externí odkaz:
https://doaj.org/article/9ff805450a664b2685d2239252277de8
Autor:
Stijntje Hibender, Barbara J.M. Mulder, Carlie J.M. de Vries, Anique ter Braake, Aeilko H. Zwinderman, Maurice J. van den Hoff, Esther Lutgens, M. Groenink, Edith E. Schermer, Romy Franken, Y. M. Pinto, Cindy van Roomen, Vivian de Waard, Quinn Gunst, Ingeborg van der Made
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, 36(8), 1618-1626. Lippincott Williams and Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology, 36, 1618-26
Arteriosclerosis, Thrombosis, and Vascular Biology, 36, 8, pp. 1618-26
Arteriosclerosis, Thrombosis, and Vascular Biology, 36, 1618-26
Arteriosclerosis, Thrombosis, and Vascular Biology, 36, 8, pp. 1618-26
Objective— Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 gene. Patients with MFS are at risk of aortic aneurysm formation and dissection. Usually, blood pressure–lowering drugs are used to reduce aor
Autor:
Shaynah Wanga, Stijntje Hibender, Yanto Ridwan, Cindy van Roomen, Mariska Vos, Ingeborg van der Made, Nicole van Vliet, Romy Franken, Maarten Groenink, Aeilko H Zwinderman, Barbara J Mulder, Carlie J de Vries, Jeroen Essers, Vivian de Waard
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Marfan syndrome (MFS) is a genetic connective tissue disorder, in which aortic rupture is the major cause of death. MFS patients with an aortic diameter below the advised limit for prophylactic surgery (C1039G/+ MFS aortic SMCs, ALP mRNA and activity
Autor:
Shaynah, Wanga, Stijntje, Hibender, Yanto, Ridwan, Cindy, van Roomen, Mariska, Vos, Ingeborg, van der Made, Nicole, van Vliet, Romy, Franken, Luigi Amjg, van Riel, Maarten, Groenink, Aeilko H, Zwinderman, Barbara Jm, Mulder, Carlie Jm, de Vries, Jeroen, Essers, Vivian, de Waard
Publikováno v:
The Journal of pathology. 243(3)
Marfan syndrome (MFS) is a connective tissue disorder in which aortic rupture is the major cause of death. MFS patients with an aortic diameter below the advised limit for prophylactic surgery (5 cm) may unexpectedly experience an aortic dissection o
Autor:
Johannes M, Aerts, Rolf G, Boot, Marco, van Eijk, Johanna, Groener, Nora, Bijl, Elisa, Lombardo, Florence M, Bietrix, Nick, Dekker, Albert K, Groen, Roelof, Ottenhoff, Cindy, van Roomen, Jan, Aten, Mireille, Serlie, Mirjam, Langeveld, Tom, Wennekes, Hermen S, Overkleeft
Publikováno v:
Advances in experimental medicine and biology. 721
Glycosphingolipids are structural membrane components, residing largely in the plasma membrane with their sugar-moieties exposed at the cell's surface. In recent times a crucial role for glycosphingolipids in insulin resistance has been proposed. A c