Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cindy X. Fang"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 295:H1206-H1215
Cellular hypertrophy is regulated by coordinated pro- and antigrowth machineries. Foxo transcription factors initiate an atrophy-related gene program to counter hypertrophic growth. This study was designed to evaluate the role of Akt, the forkhead tr
Publikováno v:
Experimental Neurology. 203:196-204
Alcohol intake is one of the important lifestyle factors for the risk of insulin resistance and type 2 diabetes. Acetaldehyde, the major ethanol metabolite which is far more reactive than ethanol, has been postulated to participate in alcohol-induced
Publikováno v:
Life Sciences. 80:187-192
Mice are extensively used for gene modification research and isolated cardiomyocytes are essential for evaluation of cardiac function without interference from non-myocyte contribution. This study was designed to characterize cardiomyocyte excitation
Publikováno v:
Stroke. 37:1875-1882
Background and Purpose— The sequelae of intracerebral hemorrhage involve multiple organ damage including electrocardiographic alteration, although the mechanism(s) behind myocardial dysfunction is unknown. The aim of this study was to examine the i
Publikováno v:
Acta Pharmacologica Sinica. 27:536-542
Aim: Ginkgo biloba extract is a natural product used widely for cerebral and cardiovascular diseases. It is mainly composed of terpene lactones (ginkgolide A and B) and flavone glycosides (eg quercetin and kaempferol). To better understand the cardia
Publikováno v:
Aging Cell. 5:177-185
Aging is often accompanied by reduced insulin sensitivity and cardiac dysfunction. However, the causal relationship between the two remains poorly understood. This study was designed to determine the impact of cardiac-specific overexpression of antio
Autor:
Shi-Yan Li, Jamie R. Privratsky, Cindy X. Fang, Jun Ren, Loren E. Wold, Xiaoping Yang, Nair Sreejayan, Asli F. Ceylan-Isik
Publikováno v:
Free Radical Biology and Medicine. 40:1419-1429
Diabetic cardiomyopathy contributes to high morbidity and mortality in diabetic populations. It is manifested by compromised ventricular contraction and prolonged relaxation attributable to multiple causative factors including oxidative stress. This
Autor:
Cindy X. Fang, Shaik Shavali, Jun Ren, Manuchair Ebadi, Jinhong Duan, Renyu Sun, Shunling Dai, Sushil Sharma
Publikováno v:
Cell Biochemistry and Biophysics. 45:137-146
Although the issue of estrogen replacement therapy on cardiovascular health is debatable, it has presumable benefits for endothelial function in postmenopausal women. However, the fear of breast cancer has intimidated women contemplating estrogen tre
Autor:
Cindy X. Fang, Jun Ren
Publikováno v:
Acta Pharmacologica Sinica. 26:279-285
RhoA and Rho-kinase (ROCK) participate in a wide variety of cell signal functions such as cell growth, smooth and cardiac muscle contraction, cytoskeleton rearrangement, cell migration and proliferation. In vascular smooth muscle cells, RhoA and ROCK
Autor:
Min Du, Gabriele E. Mayer, Nair Sreejayan, Shi-Yan Li, Asli F. Ceylan-Isik, Karissa H. LaCour, Jun Ren, Xiaoping Yang, Cindy X. Fang, Christopher J. Wilbert, E. Kurt Dolence
Publikováno v:
Aging Cell. 4:57-64
Evidence suggests that aging, per se, is a major risk factor for cardiac dysfunction. Oxidative modification of cardiac proteins by non-enzymatic glycation, i.e. advanced glycation endproducts (AGEs), has been implicated as a causal factor in the agi