Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Cindy Weidmann"'
Autor:
Kevin Gonthier, Cindy Weidmann, Line Berthiaume, Cynthia Jobin, Aurélie Lacouture, Camille Lafront, Mario Harvey, Bertrand Neveu, Jérémy Loehr, Alain Bergeron, Yves Fradet, Louis Lacombe, Julie Riopel, Éva Latulippe, Chantal Atallah, Michael Shum, Jean‐Philippe Lambert, Frédéric Pouliot, Martin Pelletier, Étienne Audet‐Walsh
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2109-2125 (2023)
The androgen receptor (AR) is an established orchestrator of cell metabolism in prostate cancer (PCa), notably by inducing an oxidative mitochondrial program. Intriguingly, AR regulates cytoplasmic isocitrate dehydrogenase 1 (IDH1), but not its mitoc
Externí odkaz:
https://doaj.org/article/b60b3bf0f71f4ae9996565ed221a4aac
Autor:
Aurélie Lacouture, Yann Breton, Cindy Weidmann, Sarah-Maude Goulet, Lucas Germain, Martin Pelletier, Étienne Audet-Walsh
Publikováno v:
Environment International, Vol 179, Iss , Pp 108132- (2023)
Due to its sensitivity to hormonal signaling, the mammary gland is often referred to as a sentinel organ for the study of endocrine-disrupting chemicals (EDCs), environmental pollutants that can interfere with the estrogen signaling pathway and induc
Externí odkaz:
https://doaj.org/article/c6e49e9da0ff4b198fa3d6f11128e9e9
Autor:
Lilianne Frégeau-Proulx, Aurélie Lacouture, Line Berthiaume, Cindy Weidmann, Mario Harvey, Kevin Gonthier, Jean-François Pelletier, Bertrand Neveu, Cynthia Jobin, Dominic Bastien, Alain Bergeron, Yves Fradet, Louis Lacombe, Isabelle Laverdière, Chantal Atallah, Frédéric Pouliot, Étienne Audet-Walsh
Publikováno v:
Molecular Metabolism, Vol 62, Iss , Pp 101516- (2022)
Objective: The prostate is metabolically unique: it produces high levels of citrate for secretion via a truncated tricarboxylic acid (TCA) cycle to maintain male fertility. In prostate cancer (PCa), this phenotype is reprogrammed, making it an intere
Externí odkaz:
https://doaj.org/article/cba98d5ecfcf4c339b2304f82a4c76f3
Autor:
Lilianne Frégeau-Proulx, Aurélie Lacouture, Cindy Weidmann, Cynthia Jobin, Étienne Audet-Walsh
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101843- (2022)
The prostate is a gland that contributes to men's fertility. It is highly responsive to androgens and is often the site of carcinogenesis, as prostate cancer is the most frequent cancer in men in over a hundred countries. To study the normal prostate
Externí odkaz:
https://doaj.org/article/cceb69b2c403415781f2e2c124e2154b
Autor:
Aurélie Lacouture, Cynthia Jobin, Cindy Weidmann, Line Berthiaume, Dominic Bastien, Isabelle Laverdière, Martin Pelletier, Étienne Audet-Walsh
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Few in vitro models are used to study mammary epithelial cells (MECs), and most of these do not express the estrogen receptor α (ERα). Primary MECs can be used to overcome this issue, but methods to purify these cells generally require flow cytomet
Externí odkaz:
https://doaj.org/article/a5aeba0e35d04b9e9554cab12caf5b0b
Publikováno v:
Cancers; Volume 15; Issue 11; Pages: 3033
The aminosteroid derivative RM-581 blocks with high potency the growth of androgen-dependent (AR+) prostate cancer VCaP, 22Rv1, and LAPC-4 cells. Notably, RM-581 demonstrated superior antiproliferative activity in LAPC-4 cells compared to enzalutamid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::41499cdfdef0770ee13f0cb26b29bb7a
Autor:
Étienne Audet-Walsh, Maude Tadros, Cindy Weidmann, Raghavendra Tejo Karthik Poluri, Kevin Gonthier
Supplementary Table 1. Human qRT-PCR primers Supplementary Table 2. Human ChIP-qPCR primers Figure S1. IDH2, IDH3A, IDH3B, and IDH3G are ubiquitously expressed across the human cancer spectrum. Figure S2. Relative mRNA expression of IDH genes in LAPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df6f83ab064161d927c9e9bacdde076
https://doi.org/10.1158/1541-7786.22516110
https://doi.org/10.1158/1541-7786.22516110
Autor:
Étienne Audet-Walsh, Maude Tadros, Cindy Weidmann, Raghavendra Tejo Karthik Poluri, Kevin Gonthier
Mutations of the isocitrate dehydrogenase genes IDH1 and IDH2, key enzymes involved in citrate metabolism, are important oncogenic events in several cancer types, including in 1%–3% of all prostate cancer cases. However, if IDH1 and other IDH isofo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ec22efccf19dcd30eb47a5a20882aa
https://doi.org/10.1158/1541-7786.c.6541281
https://doi.org/10.1158/1541-7786.c.6541281
Autor:
null Kevin Gonthier, null Cindy Weidmann, null Line Berthiaume, null Cynthia Jobin, null Aurélie Lacouture, null Camille Lafront, null Mario Harvey, null Bertrand Neveu, null Jérémy Loehr, null Alain Bergeron, null Yves Fradet, null Louis Lacombe, null Julie Riopel, null Éva Latulippe, null Chantal Atallah, null Michael Shum, null Jean‐Philippe Lambert, null Frédéric Pouliot, null Martin Pelletier, null Étienne Audet‐Walsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ddf24a28337848105407f15371b6843
https://doi.org/10.1002/1878-0261.13441/v2/response1
https://doi.org/10.1002/1878-0261.13441/v2/response1
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The estrogen signaling pathway has been reported to modulate prostate cancer (PCa) progression through the activity of estrogen receptors α and β (ERα and ERβ). Given that selective estrogen receptor modulators (SERMs) are used to treat breast ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1651d0ec693acf52275588bbf14e23
http://link.springer.com/article/10.1038/s41598-020-60844-3
http://link.springer.com/article/10.1038/s41598-020-60844-3