Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cindy R. Fischer"'
Autor:
Adrienne Müller, Katharina Beck, Zoran Rancic, Cristina Müller, Cindy R. Fischer, Thomas Betzel, Philipp A. Kaufmann, Roger Schibli, Stefanie D. Kramer, Simon M. Ametamey
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Folate receptor β (FR-β) is overexpressed on activated, but not resting, macrophages involved in a variety of inflammatory and autoimmune diseases. A pivotal step in atherogenesis is the subendothelial accumulation of macrophages. In nascent lesion
Externí odkaz:
https://doaj.org/article/13c6c2694b534b779505b9ad78f298fc
Autor:
Andreas Türler, Maruta Bunka, Konstantin Zhernosekov, Roger Schibli, Cindy R. Fischer, Josefine Reber, Cristina Müller
Publikováno v:
Journal of Nuclear Medicine. 54:2168-2174
In recent years, implementation of (68)Ga-radiometalated peptides for PET imaging of cancer has attracted the attention of clinicians. Herein, we propose the use of (44)Sc (half-life = 3.97 h, average β(+) energy [Eβ(+)av] = 632 keV) as a valuable
Autor:
Timo Stellfeld, Cindy R. Fischer, Jason P. Holland, Roger Schibli, Lutz Lehmann, P. August Schubiger, Becaud Jessica, Keith Graham, Simon M. Ametamey, Linjing Mu, Ludger Dinkelborg
Publikováno v:
European Journal of Organic Chemistry. 2012:889-892
A new method for the 18F-radiolabeling of aromatic compounds based on the aromatic nucleophilic substitution (SNAr) reaction using triarylsulfonium salts has been developed. Experiments and DFT calculations indicated that sulfonium ions have the pote
Autor:
Josefine Reber, Stephanie Haller, Viola Groehn, Thomas Betzel, Cindy R. Fischer, Silvan D. Boss, Roger Schibli, Cristina Müller, Simon M. Ametamey
Publikováno v:
Bioconjugate chemistry. 27(1)
The folate receptor (FR) is upregulated in various epithelial cancer types (FR α-isoform), while healthy tissues show only restricted expression. FR-targeted imaging using folate radiopharmaceuticals is therefore a promising approach for the detecti
Autor:
Timo Stellfeld, Sandra Borkowski, Ananth Srinivasan, Simon M. Ametamey, Miljen Martic, Linjing Mu, Ludger Dinkelborg, Pius A. Schubiger, Michael Honer, Lutz Lehmann, Cindy R. Fischer, Keith Graham
Publikováno v:
Journal of Nuclear Medicine. 52:270-278
Bombesin is a peptide exhibiting high affinity for the gastrin-releasing peptide receptor (GRPr), which is highly overexpressed on prostate cancer cells. In the present study, we developed an 18F-labeled bombesin analog, 18F-BAY 86-4367, which is cur
Autor:
Adrienne, Müller, Katharina, Beck, Zoran, Rancic, Cristina, Müller, Cindy R, Fischer, Thomas, Betzel, Philipp A, Kaufmann, Roger, Schibli, Stefanie D, Krämer, Simon M, Ametamey
Publikováno v:
Molecular imaging. 13
Folate receptor β (FR-β) is overexpressed on activated, but not resting, macrophages involved in a variety of inflammatory and autoimmune diseases. A pivotal step in atherogenesis is the subendothelial accumulation of macrophages. In nascent lesion
Autor:
Philipp A. Kaufmann, Cristina Müller, Adrienne Müller, Zoran Rancic, Stefanie-Dorothea Krämer, Thomas Betzel, Katharina Beck, Cindy R. Fischer, Simon M. Ametamey, Roger Schibli
Publikováno v:
Molecular Imaging, 13 (2)
Folate receptor β (FR-β) is overexpressed on activated, but not resting, macrophages involved in a variety of inflammatory and autoimmune diseases. A pivotal step in atherogenesis is the subendothelial accumulation of macrophages. In nascent lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0251b5e6351a1a068796ed85f98fdd2
https://hdl.handle.net/20.500.11850/91941
https://hdl.handle.net/20.500.11850/91941
Publikováno v:
EJNMMI Research
Background The folate receptor (FR) is a well-established target for tumor imaging and therapy. To date, only a few 18 F-folate conjugates via 18 F-prosthetic group labeling for positron emission tomography (PET) imaging have been developed. To some
Autor:
Walter Born, Roger Schibli, Adam A. Sabile, Carmen Campanile, Bruno Fuchs, Simon M. Ametamey, Matthias J.E. Arlt, Michael Honer, Cindy R. Fischer, Patrick Brennecke, Adrienne Müller, Stefanie D. Krämer, Ana Gvozdenovic
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 54(8)
UNLABELLED: The aim of this study was to characterize the different phenotypes of osteosarcoma by PET, comparing the uptake of 3 tracers ((18)F-FDG, (18)F-fluoromisonidazole [(18)F-FMISO], and (18)F-fluoride) in preclinical mouse models that reflect
Autor:
Cristina Müller, Viola Groehn, Simon M. Ametamey, Cindy R. Fischer, Roger Schibli, Josefine Reber
Publikováno v:
Molecular imaging and biology. 15(6)
The folate receptor (FR) is a promising target for nuclear imaging due to its overexpression in many different cancer types. A drawback of using folate radioconjugates is the high accumulation of radioactivity in the kidneys. Therefore, the aim of th