Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Cindy Q Yao"'
Autor:
John M S Bartlett, Jane Bayani, Elizabeth N Kornaga, Patrick Danaher, Cheryl Crozier, Tammy Piper, Cindy Q Yao, Janet A Dunn, Paul C Boutros, Robert C Stein, OPTIMA Trial Management Group
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238593 (2020)
Multiparametric assays for risk stratification are widely used in the management of breast cancer, with applications being developed for a number of other cancer settings. Recent data from multiple sources suggests that different tests may provide di
Externí odkaz:
https://doaj.org/article/b8c93de0973747ecbb1372aabe9a7799
Autor:
Ana B Villaseñor-Altamirano, John D Watson, Stephenie D Prokopec, Cindy Q Yao, Paul C Boutros, Raimo Pohjanvirta, Jesús Valdés-Flores, Guillermo Elizondo
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0219747 (2019)
Alternative splicing is a co-transcriptional mechanism that generates protein diversity by including or excluding exons in different combinations, thereby expanding the diversity of protein isoforms of a single gene. Abnormalities in this process can
Externí odkaz:
https://doaj.org/article/ef532e52e67941e5857fd23c6a06e521
Autor:
Yunee Kim, Jouhyun Jeon, Salvador Mejia, Cindy Q Yao, Vladimir Ignatchenko, Julius O Nyalwidhe, Anthony O Gramolini, Raymond S Lance, Dean A Troyer, Richard R Drake, Paul C Boutros, O. John Semmes, Thomas Kislinger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Proteomic technologies are capable of identifying thousands of proteins in biological samples, but biomarker applications are lagging. Here the authors use Multiple Reaction Monitoring Mass Spectrometry to delineate peptide signatures that accurately
Externí odkaz:
https://doaj.org/article/1db668735dc049b6843a5ba098f31c1d
Autor:
Christine P’ng, Jeffrey Green, Lauren C. Chong, Daryl Waggott, Stephenie D. Prokopec, Mehrdad Shamsi, Francis Nguyen, Denise Y. F. Mak, Felix Lam, Marco A. Albuquerque, Ying Wu, Esther H. Jung, Maud H. W. Starmans, Michelle A. Chan-Seng-Yue, Cindy Q. Yao, Bianca Liang, Emilie Lalonde, Syed Haider, Nicole A. Simone, Dorota Sendorek, Kenneth C. Chu, Nathalie C. Moon, Natalie S. Fox, Michal R. Grzadkowski, Nicholas J. Harding, Clement Fung, Amanda R. Murdoch, Kathleen E. Houlahan, Jianxin Wang, David R. Garcia, Richard de Borja, Ren X. Sun, Xihui Lin, Gregory M. Chen, Aileen Lu, Yu-Jia Shiah, Amin Zia, Ryan Kearns, Paul C. Boutros
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-5 (2019)
Abstract Background We introduce BPG, a framework for generating publication-quality, highly-customizable plots in the R statistical environment. Results This open-source package includes multiple methods of displaying high-dimensional datasets and f
Externí odkaz:
https://doaj.org/article/4314e3a47df049aeb55750230ad05c88
Autor:
Daniel Rea, Annette Hasenburg, Greg Pond, Janet A Dunn, Keying Xu, Luc Dirix, Cindy Q. Yao, Elizabeth Mallon, Paul C. Boutros, Elizabeth Kornaga, John M. S. Bartlett, Cornelis J.H. van de Velde, Jane Bayani, Caroline Seynaeve, Christos Markopoulos, Robert Stein, Tammy Piper
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
NPJ Breast Cancer
NPJ Breast Cancer
Multiparametric assays for risk stratification are widely used in the management of both node negative and node positive hormone receptor positive invasive breast cancer. Recent data from multiple sources suggests that different tests may provide dif
Autor:
Nicholas K. Wang, Alexandre Rouette, Kathleen E. Houlahan, Takafumi N. Yamaguchi, Julie Livingstone, Chol-Hee Jung, Peter Georgeson, Michael Fraser, Yu-Jia Shiah, Cindy Q. Yao, Vincent Huang, Natalie S. Fox, Natalie Kurganovs, Katayoon Kasaian, Veronica Y. Sabelnykova, Jay Jayalath, Kenneth Weke, Helen Zhu, Theodorus van der Kwast, Tony Papenfuss, Housheng H. He, Niall M. Corcoran, Robert G. Bristow, Alexandre R. Zlotta, Christopher Hovens, Paul C. Boutros
Publikováno v:
Cancer Research. 83:4305-4305
Inherited genetic variation profoundly influences cancer risk and outcome. While the impact of germline single nucleotide polymorphisms has been well-studied in several cancer types, the effects of germline structural variants (gSVs) on cancer biolog
Autor:
Julie Livingstone, Lincoln Stein, Cheryl Crozier, Gun Ho Jang, Cindy Q. Yao, Melanie Spears, Lauren Bathurst, Paul C. Boutros, John Douglas Mcpherson, Jane Bayani, Daniel Rea, Quang M. Trinh, Elizabeth N. Kornaga, Irina Kalatskaya, John M. S. Bartlett
Publikováno v:
JCO Precision Oncology. :1-13
PURPOSE Hormone receptor–positive breast cancer remains an ongoing therapeutic challenge, despite optimal anti-endocrine therapies. In this study, we assessed the prognostic ability of genomic signatures to identify patients at risk for recurrence
Autor:
Michèle Orain, Lawrence E. Heisler, Alexander Gusev, Cindy Q. Yao, Matthew L. Freedman, Takafumi N. Yamaguchi, Ada Wong, Kathleen E. Houlahan, Vincent Huang, Ram Shankar Mani, Paul C. Boutros, Melvin L.K. Chua, Connor Bell, Thomas Kislinger, John Douglas Mcpherson, Lee Timms, Susmita G. Ramanand, Housheng Hansen He, Jiapei Yuan, Alain Bergeron, Hélène Hovington, Julie Livingstone, Mathieu Lupien, Shadrielle Melijah G. Espiritu, Yves Fradet, Mark Pomerantz, Edward P. O’Connor, Valérie Picard, Anamay Shetty, Alex Murison, Bogdan Pasaniuc, Bernard Têtu, Theodorus van der Kwast, Louis Lacombe, Yu Jia Shiah, Michelle Sam, Jeremy Johns, Alexandre Rouette, Michael Fraser, Ankit Sinha, Adrien Foucal, Robert G. Bristow, Musaddeque Ahmed
Publikováno v:
Nature Medicine. 25:1615-1626
Oncogenesis is driven by germline, environmental and stochastic factors. It is unknown how these interact to produce the molecular phenotypes of tumors. We therefore quantified the influence of germline polymorphisms on the somatic epigenome of 589 l
Autor:
Robert G. Bristow, Jessica Ray, Honglei Xie, Carmelle Cuizon, Danny Vesprini, Kristina Commisso, Cindy Q. Yao, Jouhyun Jeon, Neil Fleshner, Andrew Loblaw, Paul C. Boutros, Fang Zhao, Michelle R. Downes, Sahar Jahangiri, Bharati Bapat, Ekaterina Olkhov-Mitsel, Renu Jeyapala, Seville Scarcello, Michael Fraser, Stanley K. Liu, John D. Watson
Publikováno v:
Journal of the National Cancer Institute, vol 112, iss 3
J Natl Cancer Inst
J Natl Cancer Inst
Background The development of noninvasive tests for the early detection of aggressive prostate tumors is a major unmet clinical need. miRNAs are promising noninvasive biomarkers: they play essential roles in tumorigenesis, are stable under diverse an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bda078c1bf41ac97552872c9128d779
https://escholarship.org/uc/item/5x31n72z
https://escholarship.org/uc/item/5x31n72z
Autor:
Alister D'Costa, Cindy Q. Yao, Mitch Levine, M-A Quintayo, Melanie Spears, T. O. Nielsen, Chris Twelves, Jms Bartlett, Nicola Lyttle, Jane Bayani, Lois E. Shepherd, Linda Liao, KI Pritchard, Elizabeth N. Kornaga, Paul C. Boutros
Publikováno v:
Cancer Research. 78:P2-10
Background: The use of anthracycline-based chemotherapies has improved overall and disease free survival in breast cancer. However, anthracyclines can have significant toxicities including cardiotoxicity and leukemia. It is, therefore, imperative to