Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cindy P van Roomen"'
Autor:
Hung-Jen Chen, Daniel C. Sévin, Guillermo R. Griffith, Johanna Vappiani, Lee M. Booty, Cindy P.A.A. van Roomen, Johan Kuiper, Jeroen den Dunnen, Wouter J. de Jonge, Rab K. Prinjha, Palwinder K. Mander, Paola Grandi, Beata S. Wyspianska, Menno P.J. de Winther
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114741- (2024)
Summary: Macrophages exhibit diverse phenotypes and respond flexibly to environmental cues through metabolic remodeling. In this study, we present a comprehensive multi-omics dataset integrating intra- and extracellular metabolomes with transcriptomi
Externí odkaz:
https://doaj.org/article/ae89bd3f7a5c4e6f9f0d1640e1046c34
Autor:
Karl J. Harber, Annette E. Neele, Cindy PAA. van Roomen, Marion JJ. Gijbels, Linda Beckers, Myrthe den Toom, Bauke V. Schomakers, Daan AF. Heister, Lisa Willemsen, Guillermo R. Griffith, Kyra E. de Goede, Xanthe AMH. van Dierendonck, Myrthe E. Reiche, Aurélie Poli, Frida L-H Mogensen, Alessandro Michelucci, Sanne GS. Verberk, Helga de Vries, Michel van Weeghel, Jan Van den Bossche, Menno PJ. de Winther
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103054- (2024)
Inflammatory macrophages are key drivers of atherosclerosis that can induce rupture-prone vulnerable plaques. Skewing the plaque macrophage population towards a more protective phenotype and reducing the occurrence of clinical events is thought to be
Externí odkaz:
https://doaj.org/article/7cec2f81eb784b929ea89dd94752aa37
Autor:
Winnie G. Vos, Bram W. van Os, Myrthe den Toom, Linda Beckers, Cindy P.A.A. van Roomen, Claudia M. van Tiel, Bhopal C. Mohapatra, Hamid Band, Katrin Nitz, Christian Weber, Dorothee Atzler, Menno P.J. de Winther, Laura A. Bosmans, Esther Lutgens, Tom T.P. Seijkens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAtherosclerosis is a lipid-driven inflammatory disease of the arterial wall, and the underlying cause of the majority of cardiovascular diseases. Recent advances in high-parametric immunophenotyping of immune cells indicate that T cells c
Externí odkaz:
https://doaj.org/article/17ccf05dbe754c14b60fa4b6e02d7e09
Autor:
Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze, Annette E. Neele, Saskia van der Velden, Marion J.J. Gijbels, Cindy P.P.A. van Roomen, Sharon G. Bernard, Wouter J. de Jonge, Inmaculada Rioja, Rab K. Prinjha, Huw D. Lewis, Palwinder K. Mander, Menno P.J. de Winther
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Monocytes and macrophages are key drivers in the pathogenesis of inflammatory diseases. Epigenetic targets have been shown to control the transcriptional profile and phenotype of these cells. Since histone deacetylase protein inhibitors demonstrate p
Externí odkaz:
https://doaj.org/article/0bd1c20ec87342d695539812e636ba12
Autor:
Lejla Medzikovic, Cindy P van Roomen, Antonius Baartscheer, Esther E Creemers, Carol Ann Remme, Karin Arkenbout, Carlie J de Vries, Vivian de Waard
Publikováno v:
Circulation Research. 121
Cardiac function is modulated by the sympathetic nervous system via catecholamines released from cardiac sympathetic nerve endings and adrenal chromaffin cells. The co-transmitter Neuropeptide Y (NPY) is co-released with catecholamines and also modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc19638a7db0938d9b315182a0f433b
https://doi.org/10.1161/res.121.suppl_1.477
https://doi.org/10.1161/res.121.suppl_1.477