Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cindy Oh"'
Autor:
Tanios Bekaii-Saab, Takuji Okusaka, David Goldstein, Do-Youn Oh, Makoto Ueno, Tatsuya Ioka, Weijia Fang, Eric C. Anderson, Marcus S. Noel, Michele Reni, Hye Jin Choi, Jonathan S. Goldberg, Sang Cheul Oh, Chung-Pin Li, Josep Tabernero, Jian Li, Emma Foos, Cindy Oh, Eric Van Cutsem
Publikováno v:
EClinicalMedicine, Vol 58, Iss , Pp 101897- (2023)
Summary: Background: Compared with normal cells, tumour cells contain elevated levels of reactive oxygen species (ROS). Increased levels of the antioxidant protein NAD(P)H:quinone oxidoreductase 1 (NQO1) and phosphorylated signal transducer and activ
Externí odkaz:
https://doaj.org/article/5dbeea00320a4570827b5add5de5eb9c
Autor:
Manish A. Shah, Kohei Shitara, Florian Lordick, Yung-Jue Bang, Niall C. Tebbutt, Jean-Phillippe Metges, Kei Muro, Keun-Wook Lee, Lin Shen, Sergei Tjulandin, John L. Hays, Naureen Starling, Rui-Hua Xu, Keren Sturtz, Marilyn Fontaine, Cindy Oh, Emily M. Brooks, Bo Xu, Wei Li, Chiang J. Li, Laura Borodyansky, Eric Van Cutsem
Publikováno v:
Clinical Cancer Research. 28:3686-3694
Purpose: To compare napabucasin (generator of reactive oxygen species) plus paclitaxel with paclitaxel only in patients with second-line advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma. Patients and Methods: In the double-blind, ph
Autor:
Tanios Bekaii-Saab, Takuji Okusaka, David Goldstein, Do-Youn Oh, Makoto Ueno, Tatsuya Ioka, Weijia Fang, Eric C. Anderson, Marcus S. Noel, Michele Reni, Hye Jin Choi, Jonathan S. Goldberg, Sang Cheul Oh, Chung-Pin Li, Josep Tabernero, Jian Li, Emma Foos, Cindy Oh, Eric Van Cutsem
Publikováno v:
Scientia
Adenocarcinoma; Napabucasin; Pancreatic cancer Adenocarcinoma; Napabucasin; Càncer de pàncrees Adenocarcinoma; Napabucasin; Cáncer de páncreas Background Compared with normal cells, tumour cells contain elevated levels of reactive oxygen species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ae2589e07e98d75566bdc3da56cba0
https://hdl.handle.net/11351/9288
https://hdl.handle.net/11351/9288
Autor:
Eric Van Cutsem, Laura Borodyansky, Chiang J. Li, Wei Li, Bo Xu, Emily M. Brooks, Cindy Oh, Marilyn Fontaine, Keren Sturtz, Rui-Hua Xu, Naureen Starling, John L. Hays, Sergei Tjulandin, Lin Shen, Keun-Wook Lee, Kei Muro, Jean-Phillippe Metges, Niall C. Tebbutt, Yung-Jue Bang, Florian Lordick, Kohei Shitara, Manish A. Shah
Supplementary Table from Randomized, Double-Blind, Placebo-Controlled Phase III Study of Paclitaxel ± Napabucasin in Pretreated Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8392c2068babbdaae28cf4c15c5c33
https://doi.org/10.1158/1078-0432.22486626.v1
https://doi.org/10.1158/1078-0432.22486626.v1
Autor:
Eric Van Cutsem, Laura Borodyansky, Chiang J. Li, Wei Li, Bo Xu, Emily M. Brooks, Cindy Oh, Marilyn Fontaine, Keren Sturtz, Rui-Hua Xu, Naureen Starling, John L. Hays, Sergei Tjulandin, Lin Shen, Keun-Wook Lee, Kei Muro, Jean-Phillippe Metges, Niall C. Tebbutt, Yung-Jue Bang, Florian Lordick, Kohei Shitara, Manish A. Shah
Supplementary Data from Randomized, Double-Blind, Placebo-Controlled Phase III Study of Paclitaxel ± Napabucasin in Pretreated Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46830c5a266b6afeb765facb985f670f
https://doi.org/10.1158/1078-0432.22486647.v1
https://doi.org/10.1158/1078-0432.22486647.v1
Autor:
Eric Van Cutsem, Laura Borodyansky, Chiang J. Li, Wei Li, Bo Xu, Emily M. Brooks, Cindy Oh, Marilyn Fontaine, Keren Sturtz, Rui-Hua Xu, Naureen Starling, John L. Hays, Sergei Tjulandin, Lin Shen, Keun-Wook Lee, Kei Muro, Jean-Phillippe Metges, Niall C. Tebbutt, Yung-Jue Bang, Florian Lordick, Kohei Shitara, Manish A. Shah
Supplementary Figure from Randomized, Double-Blind, Placebo-Controlled Phase III Study of Paclitaxel ± Napabucasin in Pretreated Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6f3188dd3e75b74298447e6f0924f2
https://doi.org/10.1158/1078-0432.22486635.v1
https://doi.org/10.1158/1078-0432.22486635.v1
Autor:
Eric Van Cutsem, Laura Borodyansky, Chiang J. Li, Wei Li, Bo Xu, Emily M. Brooks, Cindy Oh, Marilyn Fontaine, Keren Sturtz, Rui-Hua Xu, Naureen Starling, John L. Hays, Sergei Tjulandin, Lin Shen, Keun-Wook Lee, Kei Muro, Jean-Phillippe Metges, Niall C. Tebbutt, Yung-Jue Bang, Florian Lordick, Kohei Shitara, Manish A. Shah
Purpose:To compare napabucasin (generator of reactive oxygen species) plus paclitaxel with paclitaxel only in patients with second-line advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma.Patients and Methods:In the double-blind, phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8728ebd6e302e9c514b9903ee803b6b5
https://doi.org/10.1158/1078-0432.c.6532362.v1
https://doi.org/10.1158/1078-0432.c.6532362.v1
Autor:
Manish A, Shah, Kohei, Shitara, Florian, Lordick, Yung-Jue, Bang, Niall C, Tebbutt, Jean-Phillippe, Metges, Kei, Muro, Keun-Wook, Lee, Lin, Shen, Sergei, Tjulandin, John L, Hays, Naureen, Starling, Rui-Hua, Xu, Keren, Sturtz, Marilyn, Fontaine, Cindy, Oh, Emily, Brooks, Bo, Xu, Wei, Li, Chiang J, Li, Laura, Borodyansky, Eric, Van Cutsem
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
To compare napabucasin (generator of reactive oxygen species) plus paclitaxel with paclitaxel only in patients with second-line advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma.In the double-blind, phase III BRIGHTER study (NCT02178
Autor:
Claudia Lebedinsky, Suha Sari, Marilyn Fontaine, Emma Foos, Manish A. Shah, Ewa Wybieralska, Derek J. Jonker, Kamesh Kuchimanchi, Tanios Bekaii-Saab, Matthew Hitron, Cindy Oh, Emily Brooks, Bo Xu
Publikováno v:
Journal of Clinical Oncology. 39:4147-4147
4147 Background: Retrospective studies of phosphorylated STAT3 (pSTAT3, a regulator of gene expression) in cancer-lineage cells have suggested it is a biomarker of poor prognosis. We analyzed data from 3 phase 3 RCTs (BRIGHTER [T1; NCT02178956], CO.2
Autor:
Tanios Bekaii-Saab, Wahid Hanna, Laura Borodyansky, Sameh Mikhail, Alexander Starodub, Yue Chang, Cindy Oh, Wei Li, Xiaoshu Dai, Walid L. Shaib, Safi Shahda, Chiang Li, Anterpreet S. Neki, Anne M. Noonan, Bert H. O'Neil, Bassel F. El-Rayes, Emily Brooks
Publikováno v:
Journal of Clinical Oncology. 36:4110-4110
4110Background: NAPA is an oral investigational agent, hypothesized to inhibit cancer stemness pathways, including STAT3 pathway implicated in cancer stem-cell viability. We report updated data in ...