Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cindy M. Pudiak"'
Publikováno v:
Neuropharmacology. 135
N-acetylcysteine and bupropion are two promising candidate medications for treatment of substance use disorder. The effects of N-acetylcysteine or bupropion on methamphetamine self-administration of female rats are not well understood. To fill this g
Autor:
Ryan D Simonak, Joris de Wit, Michel Barrot, Joost Verhaagen, Cindy M. Pudiak, Eric J. Nestler, Amelia J. Eisch, Carlos A. Bolaños
Publikováno v:
Biological Psychiatry, 54(10), 994-1005. Elsevier USA
Eisch, A J, Bolanos, C A, de Wit, J, Simonak, R D, Pudiak, C M, Barrot, M, Verhaagen, J & Nestler, E J 2003, ' Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: A role in depression ', Biological Psychiatry, vol. 54, no. 10, pp. 994-1005 . https://doi.org/10.1016/j.biopsych.2003.08.003
Eisch, A J, Bolanos, C A, de Wit, J, Simonak, R D, Pudiak, C M, Barrot, M, Verhaagen, J & Nestler, E J 2003, ' Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: A role in depression ', Biological Psychiatry, vol. 54, no. 10, pp. 994-1005 . https://doi.org/10.1016/j.biopsych.2003.08.003
Background: Previous work has shown that brain-derived neurotrophic factor (BDNF) and its receptor, tyrosine kinase receptor B (TrkB), are involved in appetitive behavior. Here we show that BDNF in the ventral tegmental area-nucleus accumbens (VTA-NA
Autor:
Susanne M. Mumby, George K. Aghajanian, Yan G. Ni, Amy E. Herman, Bryan W. Potts, Stephen J. Gold, Rong-Jian Liu, Eric J. Nestler, Ming-Hu Han, Cindy M. Pudiak
Publikováno v:
European Journal of Neuroscience. 17:971-980
The present study explored a possible role for RGS (regulators of G protein signalling) proteins in the long term actions of morphine in the locus coeruleus (LC), a brainstem region implicated in opiate physical dependence and withdrawal. Morphine in
Publikováno v:
Psychopharmacology. 164:200-206
Rationale. Previous studies have shown that buprenorphine differentially suppresses the reinforcing effects of different drugs (cocaine, alfentanil), drug versus nondrug reinforcers (food, drug), and the same reinforcer (food) maintained under differ
Publikováno v:
Journal of Neurochemistry. 82:828-838
G protein-coupled receptor (GPCR) signaling cascades may be key substrates for the antidepressant effects of chronic electroconvulsive seizures (ECS). To better understand changes in these signaling pathways, alterations in levels of mRNA's encoding
Publikováno v:
Pharmacology, biochemistry, and behavior. 122
This study examined tolerance to cocaine's threshold-lowering effect in brain stimulation reward (BSR) following continuous cocaine infusions and secondly, used the nitric oxide synthase inhibitor Nω-nitro-L-arginine methyl ester (L-NAME) to determi
Autor:
Cindy M. Pudiak, Michael A. Bozarth
Publikováno v:
The International journal of neuroscience. 123(9)
This study determined if Nω-nitro-L-arginine methyl ester hydrochloride (L-NAME) administered after the cocaine-conditioning trial attenuated the development of sensitization to cocaine's locomotor-stimulating effect and secondly, determined if L-NA
Autor:
Michael A. Bozarth, Cindy M. Pudiak
Publikováno v:
Life Sciences. 55:PL379-PL382
Laboratory rats injected daily with a moderate dose of cocaine hydrochloride (30 mg/kg, i.p.) showed increased fatalities when cocaine injections were followed by 30 min of restraint stress. The 5-day mortality rate was 58% for the cocaine-plus-stres
Autor:
Cindy M. Pudiak, Michael A. Bozarth
Publikováno v:
Life Sciences. 53:1517-1524
Locomotor activity was tested daily following cocaine injections across 21 consecutive days. Subjects were pretreated 30-min before testing with physiological saline, the nitric oxide synthase inhibitor Nω-nitro-L-arginine (L-NAME), or the NMDA-rece
Autor:
Stephen J, Gold, Ming-Hu, Han, Amy E, Herman, Yan G, Ni, Cindy M, Pudiak, George K, Aghajanian, Rong-Jian, Liu, Bryan W, Potts, Susanne M, Mumby, Eric J, Nestler
Publikováno v:
The European journal of neuroscience. 17(5)
The present study explored a possible role for RGS (regulators of G protein signalling) proteins in the long term actions of morphine in the locus coeruleus (LC), a brainstem region implicated in opiate physical dependence and withdrawal. Morphine in