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pro vyhledávání: '"Cindy M Figueroa"'
Autor:
Yamixa Delgado, Moraima Morales-Cruz, Cindy M. Figueroa, José Hernández-Román, Glinda Hernández, Kai Griebenow
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 397-404 (2015)
Lipid–protein complexes comprised of oleic acid (OA) non‐covalently coupled to human/bovine α‐lactalbumin, named HAMLET/BAMLET, display cytotoxic properties against cancer cells. However, there is still a substantial debate about the role of t
Externí odkaz:
https://doaj.org/article/44894579a6bb41eb860c1f5402b59bae
Autor:
Anamaris Torres, Betzaida Castillo, Kai Griebenow, Moraima Morales-Cruz, Anna M. Molina, Yamixa Delgado, Melissa Milian, Cindy M Figueroa
Publikováno v:
Drug Design, Development and Therapy. 13:3753-3772
Cancer is the second largest cause of death worldwide with the number of new cancer cases predicted to grow significantly in the next decades. Biotechnology and medicine can and should work hand-in-hand to improve cancer diagnosis and treatment effic
Autor:
Laura Muñoz-Perez, Kai Griebenow, Sergio A. Loza-Rosas, Moraima Morales-Cruz, Arthur D. Tinoco, Mikhail Inyushin, Cindy M Figueroa, Lilia Kucheryavykh, Tania González-Robles, Anna M. Molina, Josue Davila, Alejandra Cruz-Montañez
Publikováno v:
Molecular Pharmaceutics. 13:2844-2854
Proteins often possess highly specific biological activities that make them potential therapeutics, but their physical and chemical instabilities during formulation, storage, and delivery have limited their medical use. Therefore, engineering of nano
Smart Release Nano-formulation of Cytochrome C and Hyaluronic Acid Induces Apoptosis in Cancer Cells
Publikováno v:
Journal of nanomedicine & nanotechnology
Herein we tested a nanosized cancer-cell targeted delivery system based on cytochrome c (Cyt c) and hyaluronic acid. Cyt c was chosen since it is a per se non-toxic protein but causes apoptosis when delivered to the cytoplasm of target cells. Hyaluro
Autor:
Tania González-Robles, Alejandra Cruz, Laura Muñoz, Cindy M Figueroa, Moraima Morales-Cruz, Kai Griebenow, Anna M. Molina
Publikováno v:
The FASEB Journal. 29
Autor:
Marimar Benítez, Cindy M Figueroa, Anna M. Molina, Kai Griebenow, Kiara Berríos, Moraima Morales-Cruz
Publikováno v:
Journal of Nanomedicine & Nanotechnology.
Photodynamic cancer therapy is still limited in its efficiency because of a lack of targeted methods avoiding non-specific toxicity. To overcome this we developed a system that is solely effective upon cellular uptake and intracellular activation by
Autor:
Yamixa Delgado, Cindy M Figueroa, Moraima Morales-Cruz, Kai Griebenow, Tania J. Gonzalez-Robles, Jessica Méndez, Anna M. Molina, Myraida Morales
Publikováno v:
Journal of Nanobiotechnology
Background Cytochrome c is an essential mediator of apoptosis when it is released from the mitochondria to the cytoplasm. This process normally takes place in response to DNA damage, but in many cancer cells (i.e., cancer stem cells) it is disabled d
Autor:
Myraida Morales, Kai Griebenow, Yamixa Delgado, Alina Monteagudo, Elsie A. Orellano, Cindy M Figueroa, Moraima Morales Cruz, Jessica Méndez
Cytochrome c (Cyt c) is a small mitochondrial heme protein involved in the intrinsic apoptotic pathway. Once Cyt c is released into the cytosol, the caspase mediated apoptosis cascade is activated resulting in programmed cell death. Herein, we explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da827546b4605578eca6df779eeac820
https://europepmc.org/articles/PMC3905321/
https://europepmc.org/articles/PMC3905321/
Autor:
Yamixa Delgado, José Hernández-Román, Cindy M Figueroa, Moraima Morales-Cruz, Glinda Hernández, Kai Griebenow
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 397-404 (2015)
FEBS Open Bio
FEBS Open Bio
Graphical abstract
Highlights • We synthesized three different BAMLET complexes consisting of oleic acid coupled to bovine α-lactalbumin. • Oleic acid micelles alone are tumoricidal at equimolar concentrations of oleic acid bound in the BAM
Highlights • We synthesized three different BAMLET complexes consisting of oleic acid coupled to bovine α-lactalbumin. • Oleic acid micelles alone are tumoricidal at equimolar concentrations of oleic acid bound in the BAM