Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Cindy Lou Chepanoske"'
Autor:
Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt, Guang-Ho Cha, Lubna Ukani, Cindy Lou Chepanoske, Yuejun Zhen, Sudhir Sahasrabudhe, James Olson, Cornelia Kurschner, Lisa M Ellerby, John M Peltier, Juan Botas, Robert E Hughes
Publikováno v:
PLoS Genetics, Vol 3, Iss 5, p e82 (2007)
Huntington's disease (HD) is a fatal neurodegenerative condition caused by expansion of the polyglutamine tract in the huntingtin (Htt) protein. Neuronal toxicity in HD is thought to be, at least in part, a consequence of protein interactions involvi
Externí odkaz:
https://doaj.org/article/13bd083a8da44dd192d10530abf31c3c
Autor:
Mike Pyne, Paul B. Robbins, Robert R. Becklin, Kartika Widjaja, Shuping Lai, Sam Thompson, Lawrence Weir, J. Jay Boniface, Yew-Seng J. Ho, John M. Peltier, Moritz von Rechenberg, Cindy Lou Chepanoske, Peter J. Sheffield, Srdjan Askovic, Yuejun Zhen, Justin Savage, Vladimir Kery, Bonnie Richardson, Nafei Xu, Tahmina Mujtaba
Publikováno v:
International Journal of Mass Spectrometry. 238:119-130
Proteomics-based technologies have the potential to accelerate the development of drugs, but such technologies must be well integrated in order to have a positive impact. We describe, herein, a multi-step process for the discovery of protein–protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9666b69be07da92afc0c60bb54db68e8
https://doi.org/10.1016/j.ijms.2003.12.039
https://doi.org/10.1016/j.ijms.2003.12.039
Publikováno v:
Organic Letters. 2:1341-1344
[formula: see text] The DNA repair adenine glycosylase MutY efficiently recognizes 7-deaza-2'-deoxyadenosine (Z) and its nonpolar isostere 4-methylindole beta-deoxynucleoside (M) opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine (OG) and G in DNA. Both wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f3ed07877c077081c8577f8a354607
https://doi.org/10.1021/ol005831o
https://doi.org/10.1021/ol005831o
Autor:
Sheila S. David, Tsuyoshi Fujiwara, Cindy Lou Chepanoske, Silvia L. Porello, Hiroshi Sugiyama
Publikováno v:
Nucleic Acids Research. 27:3197-3204
The Escherichia coli adenine glycosylase MutY is involved in the repair of 7,8-dihydro-8-oxo-2"-deoxyguanosine (OG):A and G:A mispairs in DNA. Our approach toward understanding recognition and processing of DNA damage by MutY has been to use substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a5d928fd1af3e84809637b7c866bcf
https://doi.org/10.1093/nar/27.15.3197
https://doi.org/10.1093/nar/27.15.3197
Autor:
Bonnie Richardson, Yuejun Zhen, Moritz von Rechenberg, Cindy Lou Chepanoske, Nafei Xu, Vladimir Kery, Brian Kelly Blake, Yew-Seng J. Ho
Publikováno v:
Proteomics. 5(7)
The identification and validation of the targets of active compounds identified in cell-based assays is an important step in preclinical drug development. New analytical approaches that combine drug affinity pull-down assays with mass spectrometry (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96fb2f38a07c3c905dcb4335fb39b81
https://pubmed.ncbi.nlm.nih.gov/15761956
https://pubmed.ncbi.nlm.nih.gov/15761956
Publikováno v:
Rapid communications in mass spectrometry : RCM. 19(1)
The quantity and variable quality of data that can be generated from liquid chromatography (LC)/mass spectrometry (MS)-based proteomics analyses creates many challenges in interpreting the spectra in terms of the actual proteins in a complex sample.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411a75b1dc01d436224ed9951547402a
https://pubmed.ncbi.nlm.nih.gov/15573416
https://pubmed.ncbi.nlm.nih.gov/15573416
Autor:
Marie-Pierre Golinelli-Cohen, Cindy Lou Chepanoske, Sheila S. David, Murielle Lombard, Olga A. Lukianova
Publikováno v:
Biochemistry. 43(3)
MutY is an adenine glycosylase in the base excision repair (BER) superfamily that is involved in the repair of 7,8-dihydro-8-oxo-2'-deoxyguanosine (OG):A and G:A mispairs in DNA. MutY contains a [4Fe-4S]2+ cluster that is part of a novel DNA binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9aef77342b3b69d79858414a8d4dd40
https://pubmed.ncbi.nlm.nih.gov/14730969
https://pubmed.ncbi.nlm.nih.gov/14730969
Publikováno v:
Archives of biochemistry and biophysics. 380(1)
Escherichia coli MutY is an adenine glycosylase involved in base excision repair that recognizes OG:A (where OG = 7, 8-dihydro-8-oxo-2'-deoxyguanosine) and G:A mismatches in DNA. MutY contains a solvent-exposed polypeptide loop between two of the cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d5b5ff34ae2510e7be34cf3ab98712
https://pubmed.ncbi.nlm.nih.gov/10900127
https://pubmed.ncbi.nlm.nih.gov/10900127
Autor:
Cynthia J. Burrows, Cindy Lou Chepanoske, Sheila S. David, Scott D. Williams, Robyn P. Hickerson
Publikováno v:
Journal of the American Chemical Society. 121:9901-9902
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19043f38bf2643bef755d881acbbc5f1
https://doi.org/10.1021/ja9923484
https://doi.org/10.1021/ja9923484
Autor:
Sudhir Sahasrabudhe, Cornelia Kurschner, Robert E. Hughes, Amit Phansalkar, Linda S. Kaltenbach, Robert R. Becklin, Eliana Romero, Rakesh Chettier, Juan Botas, Lubna Ukani, Russell Bell, Anthony Hurlburt, Cameron Torcassi, Yuejun Zhen, John M. Peltier, James M. Olson, Justin Savage, Cindy Lou Chepanoske, Lisa M. Ellerby, Guang Ho Cha, Andrew D. Strand
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 3, Iss 5, p e82 (2007)
PLoS Genetics, Vol 3, Iss 5, p e82 (2007)
Huntington's disease (HD) is a fatal neurodegenerative condition caused by expansion of the polyglutamine tract in the huntingtin (Htt) protein. Neuronal toxicity in HD is thought to be, at least in part, a consequence of protein interactions involvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94d19b9bf2cecb2f2f040f79c491504
https://doi.org/10.1371/journal.pgen.0030082
https://doi.org/10.1371/journal.pgen.0030082