Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Cindy L. Hamil"'
Autor:
Kajsa E. Affolter, Sabine Hellwig, David A. Nix, Mary P. Bronner, Alun Thomas, Carrie L. Fuertes, Cindy L. Hamil, Ignacio Garrido-Laguna, Courtney L. Scaife, Sean J. Mulvihill, Hunter R. Underhill
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 859-869 (2021)
The confounding effects of next-generation sequencing (NGS) noise on detection of low frequency circulating tumor DNA (ctDNA) without a priori knowledge of solid tumor mutations has limited the applications of circulating cell-free DNA (ccfDNA) in cl
Externí odkaz:
https://doaj.org/article/358af70ad57a48859ddd7ab16dc40fd3
Autor:
David A Nix, Sabine Hellwig, Christopher Conley, Alun Thomas, Carrie L Fuertes, Cindy L Hamil, Preetida J Bhetariya, Ignacio Garrido-Laguna, Gabor T Marth, Mary P Bronner, Hunter R Underhill
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229063 (2020)
Challenges with distinguishing circulating tumor DNA (ctDNA) from next-generation sequencing (NGS) artifacts limits variant searches to established solid tumor mutations. Here we show early and random PCR errors are a principal source of NGS noise th
Externí odkaz:
https://doaj.org/article/5718b9aa273541e6820abd8340717128