Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cindy L. Fonseca"'
Autor:
Carolyn Marquis, Cindy L. Fonseca, Katelyn A. Queen, Lisa Wood, Sarah E. Vandal, Heidi L. H. Malaby, Joseph E. Clayton, Jason Stumpff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Kinesin motor proteins are critical for maintaining mitotic spindle integrity, which is important for chromosome stability. Here, the authors show that the kinesin motor protein, KIF18A, permits the proliferation of chromosomally unstable cells and k
Externí odkaz:
https://doaj.org/article/155fe186fe17428f9306cda918e23864
Autor:
Joseph E. Clayton, Lisa Wood, Carolyn Marquis, Heidi L.H. Malaby, Katelyn A. Queen, Sarah E. Vandal, Cindy L. Fonseca, Jason Stumpff
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Chromosomal instability (CIN) is a hallmark of tumor cells caused by changes in the dynamics and control of microtubules that compromise the mitotic spindle. Thus, CIN cells may respond differently than diploid cells to treatments that target mitotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aca43cc7a45dfc0f482c244f8260a6a
https://pubmed.ncbi.nlm.nih.gov/33619254
https://pubmed.ncbi.nlm.nih.gov/33619254
Autor:
Heidi L.H. Malaby, Candice Byers, Leslie A. Sepaniac, Cindy L. Fonseca, Whitney Martin, Dana Messinger, Ryoma Ohi, Anne Czechanski, Mary Tang, Jason Stumpff, Laura G. Reinholdt
Publikováno v:
The Journal of Cell Biology
Orr and Maiato discuss work from the Stumpff laboratory addressing the role of chromosome congression in mitotic fidelity and genomic stability.
Chromosome alignment is a hallmark of mitosis in metazoans, but the physiological relevance of this
Chromosome alignment is a hallmark of mitosis in metazoans, but the physiological relevance of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952254d3e298643b45f34d41b03b5859
https://pubmed.ncbi.nlm.nih.gov/30858193
https://pubmed.ncbi.nlm.nih.gov/30858193
Autor:
Candice Byers, Ryoma Ohi, Jason Stumpff, Messinger D, Anne Czechanski, Laura G. Reinholdt, Tang M, Heidi L.H. Malaby, Cindy L. Fonseca, Leslie A. Sepaniac, Whitney Martin
SUMMARYChromosome alignment at the equator of the mitotic spindle is a highly conserved step during cell division, however, its importance to genomic stability and cellular fitness are not understood. Normal mammalian somatic cells lacking Kif18A fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b961bae7c1b7d495c7bc60a1f2b902c
https://doi.org/10.1101/343475
https://doi.org/10.1101/343475
Publikováno v:
Molecular Biology of the Cell
Kif18A and Kif4A display a similar ability to attenuate the dynamics of microtubules but function to control the lengths of distinct subsets of spindle microtubules during mitosis. Kif18A and Kif4A are not functionally equivalent for chromosome align
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5163725e895981da7360e32261aef3a
https://doi.org/10.1091/mbc.e14-06-1132
https://doi.org/10.1091/mbc.e14-06-1132
Publikováno v:
Histochemistry and Cell Biology. 138:435-445
We hypothesized that structural remodeling associated with advancing age occurs in human saphenous veins. To address this hypothesis, we have identified structural remodeling in human saphenous veins by applying histochemistry, fluorescence staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70427bdbb70e12ffde7f65007bdf73ce
https://doi.org/10.1007/s00418-012-0966-8
https://doi.org/10.1007/s00418-012-0966-8