Population Pharmacokinetic Model of N-acetylmannosamine (ManNAc) and N-acetylneuraminic acid (Neu5Ac) in Subjects with GNE Myopathy

Autor: Scott A. Van Wart, Marjan Huizing, Nuria Carrillo, Donald E. Mager, Cindy J Bednasz

Publikováno v: Drugs in R&D

Background GNE myopathy is a rare genetic muscle disease resulting from deficiency in an enzyme critical for the biosynthesis of N-acetylneuraminic acid (Neu5Ac, sialic acid). The uncharged Neu5Ac precursor, N-acetylmannosamine (ManNAc), is under dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb0e0099a75b288121e52c5558d9e93
https://doi.org/10.1007/s40268-021-00343-6

Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202

Autor: Cindy J. Bednasz, Charles S. Venuto, Qing Ma, Eric S. Daar, Paul E. Sax, Margaret A. Fischl, Ann C. Collier, Kimberly Y. Smith, Camlin Tierney, Edward P. Acosta, Donald E. Mager, Gene D. Morse, Hector H. Bolivar, Sandra Navarro, Susan L. Koletar, Diane Gochnour, Edward Seefried, Julie Hoffman, Judith Feinberg, Michelle Saemann, Kristine Patterson, Donna Pittard, David Currin, Kerry Upton, Michael Saag, Graham Ray, Steven Johnson, Bartolo Santos, Connie A. Funk, Michael Morgan, Brenda Jackson, Pablo Tebas, Aleshia Thomas, Ge-Youl Kim, Michael K. Klebert, Jorge L. Santana, Santiago Marrero, Jane Norris, Sandra Valle, Gary Matthew Cox, Martha Silberman, Sadia Shaik, Ruben Lopez, Margie Vasquez, Demetre Daskalakis, Christina Megill, Todd Stroberg, Jessica Shore, Babafemi Taiwo, Mitchell Goldman, Molly Boston, Jeffrey Lennox, Carlos del Rio, Timothy W. Lane, Kim Epperson, Annie Luetkemeyer, Mary Payne, Barbara Gripshover, Dawn Antosh, Jane Reid, Mary Adams, Sheryl S. Storey, Shelia B. Dunaway, Joel Gallant, Ilene Wiggins, Joan A. Swiatek, Joseph Timpone, Princy Kumar, Ardis Moe, Maria Palmer, Jon Gothing, Joanne Delaney, Kim Whitely, Ann Marie Anderson, Scott M. Hammer, Michael T. Yin, Mamta Jain, Tianna Petersen, Roberto Corales, Christine Hurley, Keith Henry, Bette Bordenave, Amanda Youmans, Mary Albrecht, Richard B. Pollard, Abimbola Olusanya, Paul R. Skolnik, Betsy Adams, Karen T. Tashima, Helen Patterson, Michelle Ukwu, Lauren Rogers, Henry H. Balfour, Kathy A. Fox, Susan Swindells, Frances Van Meter, Gregory Robbins, Nicole Burgett-Yandow, Charles E. Davis, Colleen Boyce, William A. O’Brien, Gerianne Casey, Chiu-Bin Hsaio, Jeffrey L. Meier, Jack T. Stapleton, Donna Mildvan, Manuel Revuelta, Wafaa El Sadr, Avelino Loquere, Nyef El-Daher, Tina Johnson, Robert Gross, Kathyrn Maffei, Valery Hughes, Glenn Sturge, Deborah McMahon, Barbara Rutecki, Michael Wulfsohn, Andrew Cheng, Norbert Bischofberger, Lynn Dix, Qiming Liao

Publikováno v: Antimicrobial Agents and Chemotherapy. 63

AIDS Clinical Trial Group study A5202 (ClinicalTrials.gov identifier {"type":"clinical-trial","attrs":{"text":"NCT00118898","term_id":"NCT00118898"}}NCT00118898) was a phase 3b, randomized, partially blinded equivalence study of open-label atazanavir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb699c7a56c4daf00428d4513ced434
https://doi.org/10.1128/aac.01638-18

Translational pharmacology and HIV reservoir eradication strategies

Autor: Cindy J Bednasz, Gene D. Morse, Qing Ma

Publikováno v: Future Virology. 12:631-633

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b7b36520d369926d2bdd54cf62ccefb
https://doi.org/10.2217/fvl-2017-0091

Recent advances in management of the HIV/HCV coinfected patient

Autor: Anthony Martinez, Holly R Hamilton, Cindy J Bednasz, Farzia S Kaufman, Andrew H. Talal, Gene D. Morse, Charles S. Venuto, Qing Ma, Joshua R. Sawyer, Patrick G Rose, Samantha S Sithole

Publikováno v: Future virology. 10(8)

Chronic hepatitis C virus (HCV) is a global epidemic, affecting approximately 150 million individuals throughout the world. The implications of HCV infection have been magnified in those who are infected with both HCV and the HIV as liver disease pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc853b92934d50daba3d9db2aa1c41d
https://pubmed.ncbi.nlm.nih.gov/26877758