An Untethered Heart Rhythm Monitoring System with Automated AI‐Based Arrhythmia Detection for Closed‐Loop Experimental Application

Autor: Shanliang Deng, Bram L den Ouden, Tim De Coster, Cindy I Bart, Wilhelmina H Bax, René H Poelma, Antoine AF de Vries, Guo Qi Zhang, Vincent Portero, Daniël A Pijnappels

Publikováno v: Advanced Sensor Research, Vol 3, Iss 11, Pp n/a-n/a (2024)

Abstract The heart produces bioelectrical signals, which can be measured as an electrocardiogram (ECG) for the detection of rhythm disturbances. Rapid and precise detection of these arrhythmias is crucial for their termination by closed‐looped ther

Externí odkaz: https://doaj.org/article/dd8403173be841acbac2015c78d8c49a

The Cell Strikes Back: Disease Responsive Gene Therapy for Aortic Aneurysms

Autor: Natalija Bogunovic, Cindy I. Bart, Juan Zhang, Kak K. Yeung, Antoine A.F. de Vries

Publikováno v: AORTA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4521184d649b07b89d40a5cbd2084ef
https://doi.org/10.1055/s-0042-1750930

The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes

Autor: Tim De Coster, Balázs Ördög, Cindy I. Bart, Antoine A.F. de Vries, J Zhang, Sven O. Dekker, Alexander S Teplenin, Dirk L. Ypey, Daniël A. Pijnappels

Publikováno v: Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, 12. FRONTIERS MEDIA SA
Frontiers in Physiology

Aim: Channelrhodopsins (ChRs) are a large family of light-gated ion channels with distinct properties, which is of great importance in the selection of a ChR variant for a given application. However, data to guide such selection for cardiac optogenet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9367d6bda2cb172fb3733932a6c21909
https://www.frontiersin.org/articles/10.3389/fphys.2021.710020/full

Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice

Autor: Niek J. Pluijmert, Douwe E. Atsma, Cindy I. Bart, Wilhelmina H. Bax, Paul H.A. Quax

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1). NATURE RESEARCH
Scientific Reports, 10(1). Nature Research

Many novel therapies to treat myocardial infarction (MI), yielding promising results in animal models, nowadays failed in clinical trials for several reasons. The most used animal MI model is based on permanent ligation of the left anterior descendin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230237f619659a16f4631a4a350e17c7
http://europepmc.org/articles/PMC7538581

An automated hybrid bioelectronic system for autogenous restoration of sinus rhythm in atrial fibrillation

Autor: Cindy I. Bart, A. Kip, Guoqi Zhang, Katja Zeppenfeld, E.C.A. Nyns, Thomas J van Brakel, Antoine A.F. de Vries, Daniël A. Pijnappels, R. H. Poelma, Martin J. Schalij, Jaap J. Plomp, L Volkers

Publikováno v: Science Translational Medicine
Science Translational Medicine, 11(481)

Because of suboptimal therapeutic strategies, restoration of sinus rhythm in symptomatic atrial fibrillation (AF) often requires in-hospital delivery of high-voltage shocks, thereby precluding ambulatory AF termination. Continuous, rapid restoration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144e3823e1f0a5bea539643754c838d9