Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cindy G. Santander"'
Autor:
Xiaodong Liu, Long Lin, Mikkel-Holger S. Sinding, Laura D. Bertola, Kristian Hanghøj, Liam Quinn, Genís Garcia-Erill, Malthe Sebro Rasmussen, Mikkel Schubert, Patrícia Pečnerová, Renzo F. Balboa, Zilong Li, Michael P. Heaton, Timothy P. L. Smith, Rui Resende Pinto, Xi Wang, Josiah Kuja, Anna Brüniche-Olsen, Jonas Meisner, Cindy G. Santander, Joseph O. Ogutu, Charles Masembe, Rute R. da Fonseca, Vincent Muwanika, Hans R. Siegismund, Anders Albrechtsen, Ida Moltke, Rasmus Heller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The blue wildebeest (Connochaetes taurinus) is a keystone species in savanna ecosystems from southern to eastern Africa, and is well known for its spectacular migrations and locally extreme abundance. In contrast, the black wildebeest (C. gn
Externí odkaz:
https://doaj.org/article/f71c0996365a44c290665498362d89cb
Autor:
Renzo F. Balboa, Laura D. Bertola, Anna Brüniche-Olsen, Malthe Sebro Rasmussen, Xiaodong Liu, Guillaume Besnard, Jordi Salmona, Cindy G. Santander, Shixu He, Dietmar Zinner, Miguel Pedrono, Vincent Muwanika, Charles Masembe, Mikkel Schubert, Josiah Kuja, Liam Quinn, Genís Garcia-Erill, Frederik Filip Stæger, Rianja Rakotoarivony, Margarida Henrique, Long Lin, Xi Wang, Michael P. Heaton, Timothy P. L. Smith, Kristian Hanghøj, Mikkel-Holger S. Sinding, Anagaw Atickem, Lounès Chikhi, Christian Roos, Philippe Gaubert, Hans R. Siegismund, Ida Moltke, Anders Albrechtsen, Rasmus Heller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Several African mammals exhibit a phylogeographic pattern where closely related taxa are split between West/Central and East/Southern Africa, but their evolutionary relationships and histories remain controversial. Bushpigs (Potamochoerus la
Externí odkaz:
https://doaj.org/article/fb49b35934fa4d6a852438359aab82d8
Autor:
Anne Cathrine Baun Thuesen, Frederik Filip Stæger, Alba Kaci, Marie Holm Solheim, Ingvild Aukrust, Emil Jørsboe, Cindy G. Santander, Mette K. Andersen, Zilong Li, Arthur Gilly, Sara Elizabeth Stinson, Anette Prior Gjesing, Peter Bjerregaard, Michael Lynge Pedersen, Christina Viskum Lytken Larsen, Niels Grarup, Marit E. Jørgensen, Eleftheria Zeggini, Lise Bjørkhaug, Pål Rasmus Njølstad, Anders Albrechtsen, Ida Moltke, Torben Hansen
Publikováno v:
The Lancet Regional Health-Europe
Thuesen, A C B, Stæger, F F, Kaci, A, Solheim, M H, Aukrust, I, Jørsboe, E, Santander, C G, Andersen, M K, Li, Z, Gilly, A, Stinson, S E, Gjesing, A P, Bjerregaard, P, Pedersen, M L, Larsen, C V L, Grarup, N, Jørgensen, M E, Zeggini, E, Bjørkhaug, L, Njølstad, P R, Albrechtsen, A, Moltke, I & Hansen, T 2023, ' A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland ', The Lancet Regional Health-Europe, vol. 24, 100529 . https://doi.org/10.1016/j.lanepe.2022.100529
Thuesen, A C B, Stæger, F F, Kaci, A, Solheim, M H, Aukrust, I, Jørsboe, E, Santander, C G, Andersen, M K, Li, Z, Gilly, A, Stinson, S E, Gjesing, A P, Bjerregaard, P, Pedersen, M L, Larsen, C V L, Grarup, N, Jørgensen, M E, Zeggini, E, Bjørkhaug, L, Njølstad, P R, Albrechtsen, A, Moltke, I & Hansen, T 2023, ' A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland ', The Lancet Regional Health-Europe, vol. 24, 100529 . https://doi.org/10.1016/j.lanepe.2022.100529
Background: The genetic disease architecture of Inuit includes a large number of common high-impact variants. Identification of such variants contributes to our understanding of the genetic aetiology of diseases and improves global equity in genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630bbe59ff3adfcfcc41cec4442f73bb
https://hdl.handle.net/11250/3063542
https://hdl.handle.net/11250/3063542
Autor:
José Cerca, Darko D. Cotoras, Cindy G. Santander, Vanessa C. Bieker, Leke Hutchins, Jaime Morin-Lagos, Carlos F. Prada, Susan Kennedy, Henrik Krehenwinkel, Andrew J. Rominger, Joana Meier, Dimitar Dimitrov, Torsten H. Struck, Rosemary G. Gillespie
The repeated evolution of phenotypes is ubiquitous in nature and offers some of the clearest evidence of the role of natural selection in evolution. The genomic basis of repeated phenotypic evolution is often complex and can arise from a combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d51178c5391bf9a4fd7efeba6318de4c
https://doi.org/10.1101/2022.11.29.518358
https://doi.org/10.1101/2022.11.29.518358
Autor:
Mette K. Andersen, Line Skotte, Emil Jørsboe, Ryan Polito, Frederik F. Stæger, Peter Aldiss, Kristian Hanghøj, Ryan K. Waples, Cindy G. Santander, Niels Grarup, Inger K. Dahl-Petersen, Lars J. Diaz, Maria Overvad, Ninna K. Senftleber, Bolette Søborg, Christina V.L. Larsen, Clara Lemoine, Oluf Pedersen, Bjarke Feenstra, Peter Bjerregaard, Mads Melbye, Marit E. Jørgensen, Nils J. Færgeman, Anders Koch, Thomas Moritz, Matthew P. Gillum, Ida Moltke, Torben Hansen, Anders Albrechtsen
Publikováno v:
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
BACKGROUND & AIMS: The sucrase-isomaltase (SI) c.273_274delAG loss-of-function variant is common in Arctic populations and causes congenital sucrase-isomaltase deficiency, which is an inability to break down and absorb sucrose and isomaltose. Childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af598bb6586cd15c453ff65560389ba
https://findresearcher.sdu.dk:8443/ws/files/202400420/PIIS0016508521040658.pdf
https://findresearcher.sdu.dk:8443/ws/files/202400420/PIIS0016508521040658.pdf
Autor:
Emil, Jørsboe, Mette K, Andersen, Line, Skotte, Frederik F, Stæger, Nils J, Færgeman, Kristian, Hanghøj, Cindy G, Santander, Ninna K, Senftleber, Lars J, Diaz, Maria, Overvad, Ryan K, Waples, Frank, Geller, Peter, Bjerregaard, Mads, Melbye, Christina V L, Larsen, Bjarke, Feenstra, Anders Koch, Marit E, Jørgensen, Niels, Grarup, Ida, Moltke, Anders, Albrechtsen, Torben, Hansen
Publikováno v:
HGG advances. 3(4)
The common Arctic-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0086f96edaf9650dc6bebe1b990690f8
https://pubmed.ncbi.nlm.nih.gov/36267056
https://pubmed.ncbi.nlm.nih.gov/36267056
Autor:
Emil Jørsboe, Mette K. Andersen, Line Skotte, Frederik F. Stæger, Nils J. Færgeman, Kristian Hanghøj, Cindy G. Santander, Ninna K. Senftleber, Lars J. Diaz, Maria Overvad, Ryan K. Waples, Frank Geller, Peter Bjerregaard, Mads Melbye, Christina V.L. Larsen, Bjarke Feenstra, null Anders Koch, Marit E. Jørgensen, Niels Grarup, Ida Moltke, Anders Albrechtsen, Torben Hansen
Publikováno v:
Jørsboe, E, Andersen, M K, Skotte, L, Stæger, F F, Færgeman, N J, Hanghøj, K, Santander, C G, Senftleber, N K, Diaz, L J, Overvad, M, Waples, R K, Geller, F, Bjerregaard, P, Melbye, M, Larsen, C V L, Feenstra, B, Anders Koch, K, Jørgensen, M E, Grarup, N, Moltke, I, Albrechtsen, A & Hansen, T 2022, ' An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention ', Human Genetics and Genomics Advances, vol. 3, no. 4, 100118 . https://doi.org/10.1016/j.xhgg.2022.100118
Human Genetics and Genomics Advances (HGG Advances)
Human Genetics and Genomics Advances (HGG Advances)
The common Arctic-specific LDLR p.G137S variant was recently shown to be associated with elevated lipid levels. Motivated by this, we aimed to investigate the effect of p.G137S on metabolic health and cardiovascular disease risk among Greenlanders to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810ce420bbc3628efd09f48eb36dc65e
https://doi.org/10.1016/j.xhgg.2022.100118
https://doi.org/10.1016/j.xhgg.2022.100118
Autor:
Rasmus Heller, Ryan K. Waples, Xiaodong Liu, Hans R. Siegismund, Liam Quinn, Ida Moltke, Rute R. da Fonseca, Casia Nursyifa, Christian Hviid Friis Jørgensen, Frederik Filip Stæger, Genís Garcia-Erill, Cindy G. Santander, Jonas Meisner, Patrícia Pečnerová, Anders Albrechtsen, Malthe Sebro Rasmussen, Peter Frandsen, Anna Brüniche-Olsen, Kristian Hanghøj
Publikováno v:
Pečnerová, P, Garcia-Erill, G, Liu, X, Nursyifa, C, Waples, R K, Santander, C G, Quinn, L, Frandsen, P, Meisner, J, Stæger, F F, Rasmussen, M S, Brüniche-Olsen, A, Jørgensen, C H F, da Fonseca, R R, Siegismund, H R, Albrechtsen, A, Heller, R, Moltke, I & Hanghøj, K 2021, ' High genetic diversity and low differentiation reflect the ecological versatility of the African leopard ', Current Biology, vol. 31, no. 9, pp. 1862-1871, e1-e5 . https://doi.org/10.1016/j.cub.2021.01.064
Large carnivores are generally sensitive to ecosystem changes because their specialized diet and position at the top of the trophic pyramid is associated with small population sizes. Accordingly, low genetic diversity at the whole-genome level has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f24010354aeddb2b51b4b96286bc658
https://pubmed.ncbi.nlm.nih.gov/33636121
https://pubmed.ncbi.nlm.nih.gov/33636121
Publikováno v:
Suiform Soundings. Mar2024, Vol. 22 Issue 2, p39-41. 3p.
Autor:
Liu, Xiaodong, Lin, Long, Sinding, Mikkel-Holger S., Bertola, Laura D., Hanghøj, Kristian, Quinn, Liam, Garcia-Erill, Genís, Rasmussen, Malthe Sebro, Schubert, Mikkel, Pečnerová, Patrícia, Balboa, Renzo F., Li, Zilong, Heaton, Michael P., Smith, Timothy P. L., Pinto, Rui Resende, Wang, Xi, Kuja, Josiah, Brüniche-Olsen, Anna, Meisner, Jonas, Santander, Cindy G.
Publikováno v:
Nature Communications; 4/12/2024, Vol. 15 Issue 1, p1-16, 16p