Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cindy Fishman"'
Autor:
Paul D. Benn, Ying Zhang, Lesley Kahl, Thomas J. Greene, Veronica Bainbridge, Cindy Fishman, Bo Wen, Martin Gartland
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract We report the safety and pharmacokinetic properties of the HIV‐1 maturation inhibitor GSK3739937 (GSK'937) in healthy participants. This was a phase I, first‐in‐human, double‐blind, randomized, placebo‐controlled, single‐ (part 1
Externí odkaz:
https://doaj.org/article/8a910cb4b94042ba90ad7e446d8260ac
Autor:
Susan B Laffan, Andrew S Thomson, Shing Mai, Cindy Fishman, Takahito Kambara, Kiran Nistala, James T Raymond, Shugui Chen, Thulasi Ramani, Laura Pageon, Rodd Polsky, Mark Watkins, Gemma Ottolangui, John R White, Curtis Maier, Michael Herdman, Gerben Bouma
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231655 (2020)
Despite the potential for the chemokine class as therapeutic targets in immune mediated disease, success has been limited. Many chemokines can bind to multiple receptors and many receptors have multiple ligands, with few exceptions. One of those exce
Externí odkaz:
https://doaj.org/article/ee33790a5c0946eb8e5ea303f460bcc0
Autor:
Charles Jakielaszek, Jamese J. Hilliard, Frank Mannino, Mohammad Hossain, Lian Qian, Cindy Fishman, Ying-Liang Chou, Lisa Henning, Joseph Novak, Samandra Demons, Jeremy Hershfield, Karen O’Dwyer
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Francisella tularensis ( F. tularensis ) is a Centers for Disease Control (CDC) category “A” Gram-negative biothreat pathogen. Inhalation of F. tularensis can cause pneumonia and respiratory failure and is associated with high mortality rates wit
Autor:
Cindy Fishman, Jessica M. Caverly Rae, Lorraine M. Posobiec, Susan B. Laffan, Steven A. Lerman, Neil Pearson, Salim Janmohamed, Etienne Dumont, Deatra Nunn-Floyd, Dinesh J. Stanislaus
Publikováno v:
Antimicrobial agents and chemotherapy. 66(11)
Fluoroquinolone use in children is limited due to its potential toxicity and negative effects on skeletal development, but the actual effects/risks of fluoroquinolones on bone growth and the mechanisms behind fluoroquinolone-driven arthropathy remain
Autor:
Charles Jakielaszek, Mohammad Hossain, Lian Qian, Cindy Fishman, Katherine Widdowson, Jamese J. Hilliard, Frank Mannino, Aparna Raychaudhuri, Elisabeth Carniel, Samandra Demons, Henry S. Heine, Jeremy Hershfield, Riccardo Russo, William M. Mega, David Revelli, Karen O’Dwyer
Publikováno v:
Science Translational Medicine. 14
Gepotidacin is a first-in-class triazaacenaphthylene antibacterial agent that selectively inhibits bacterial DNA gyrase and topoisomerase IV through a unique binding mode and has the potential to treat a number of bacterial diseases. Development of t