Výsledky vyhledávání - "Cindy Christopherson"

Akademický článek

Multiple metabolic alterations exist in mutant PI3K cancers, but only glucose is essential as a nutrient source.

Autor: Rebecca Foster, Sue Griffin, Suzanne Grooby, Ruth Feltell, Cindy Christopherson, Monica Chang, John Sninsky, Shirley Kwok, Chris Torrance

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45061 (2012)

Targeting tumour metabolism is becoming a major new area of pharmaceutical endeavour. Consequently, a systematic search to define whether there are specific energy source dependencies in tumours, and how these might be dictated by upstream driving ge

Externí odkaz: https://doaj.org/article/834d1b4441a949d0bfb401466e5229ca

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Validation of a Clinical-Grade Assay to Measure Donor-Derived Cell-Free DNA in Solid Organ Transplant Recipients

Autor: María G. Crespo-Leiro, J. Yee, Kathryn Thompson, Marica Grskovic, David A. Ross, Mitchell J. Nelles, Cindy Christopherson, John P. Collins, Judith C. Wilber, D. Hiller, Mindy Song, Robert Woodward, Yue S. Wang, Susan L. Scott, Lane A. Eubank, John J. Sninsky

Publikováno v: RUC. Repositorio da Universidade da Coruña
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[Abstract] The use of circulating cell-free DNA (cfDNA) as a biomarker in transplant recipients offers advantages over invasive tissue biopsy as a quantitative measure for detection of transplant rejection and immunosuppression optimization. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf708b752ac5fcd7b719d311bffc6e2d

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Abstract PD10-03: Predictive value of a proliferation score (MS) in postmenopausal women with endocrine-responsive breast cancer: results from International Breast Cancer Study Group (IBCSG) Trial IX

Autor: Alice Wang, G. Viale, Monica Chang, Brian Leyland-Jones, Robert Lagier, Meredith M. Regan, Charles M. Rowland, Roswitha Kammler, Shirley Kwok, Cindy Christopherson, John J. Sninsky, Kathryn P. Gray

Publikováno v: Cancer Research. 72:PD10-03

Background: While representing the largest fraction of women diagnosed with primary breast cancer, older postmenopausal women with ER+, HER2− tumors are less responsive to chemoendocrine therapy than younger women and have been underrepresented in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d5e135238b73ef898e58b1c72f7058c
https://doi.org/10.1158/0008-5472.sabcs12-pd10-03

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Abstract P2-09-19: Expression Profiling of a Metastasis Score and a 'Glycolytic Index' in Genetically-Defined Human Breast Isogenic Cell Lines Treated with a PI3K Inhibitor

Autor: Robert Lagier, Alice Wang, Sue Rigby, Christopher Torrance, John J. Sninsky, Shirley Kwok, Cindy Christopherson

Publikováno v: Cancer Research. 70:P2-09

Background: Activation of signaling pathways, loss of tumor suppressors and oncogenic mutations often lead to dysregulation of glycolysis and tumorigenesis. We performed expression analysis on genetically-defined human isogenic breast cancer cell lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b58bd50abae10ec8d9af1748ec5af17c
https://doi.org/10.1158/0008-5472.sabcs10-p2-09-19

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P140 HLA match and donor-derived cell-free DNA levels in kidney transplant recipients

Autor: D. Hiller, Robert Woodward, Cindy Christopherson, Susan L. Scott

Publikováno v: Human Immunology. 78:157

Aim Circulating cell-free DNA (cfDNA) has been correlated with allograft rejection in organ transplant recipients and is proposed as a biomarker to assess graft injury that may be reflective of allograft rejection or immunosuppression toxicity. We ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20a1ead7ab0e83f528d5f63588fecc39
https://doi.org/10.1016/j.humimm.2017.06.200

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PCR-Based Assay To Quantify Human Immunodeficiency Virus Type 1 DNA in Peripheral Blood Mononuclear Cells

Autor: Brian Conway, Shirley Kwok, Cindy Christopherson, Yorda Kidane, Haynes W. Sheppard, John F. Krowka

Publikováno v: Journal of Clinical Microbiology. 38:630-634

An assay that quantifies the amount of human immunodeficiency virus type 1 (HIV-1) DNA in peripheral blood mononuclear cells has been developed. PCR amplification of the HIV-1 DNA is performed in the presence of an internal quantitation standard, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b5e1d0b1675e14fdab8ed0088a4880
https://doi.org/10.1128/jcm.38.2.630-634.2000

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HIV mediates a productive infection of the brain

Autor: Guoji Wang, Eliezer Masliah, Shirley Kwok, Clayton A. Wiley, Cristian L. Achim, Cindy Christopherson, Lakshmi Radhakrishnan, Yorda Kidane, John W. Mellors, Virawudh Soontornniyomkij

Publikováno v: AIDS. 13:2055-2059

Background: Approximately one quarter of patients with AIDS develop severe cognitive deficits called HlV-associated dementia complex. There is some controversy regarding the importance of viral load and distribution in mediating this neurologic disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfa9f51d939d03a772461002470460b
https://doi.org/10.1097/00002030-199910220-00007

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Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocyte Activity Is Inversely Correlated with HIV Type 1 Viral Load in HIV Type 1-Infected Long-Term Survivors

Autor: Leslie G. Louie, John F. Krowka, Shirley Kwok, Thomas B. Kepler, Jeffrey A. Frelinger, Joseph J. Eron, Haynes W. Sheppard, Marie Davidian, Cindy Christopherson, Michael R. Betts

Publikováno v: AIDS Research and Human Retroviruses. 15:1219-1228

HIV-1-specific cytotoxic T cell (CTL) activity has been suggested to correlate with protection from progression to AIDS. We have examined the relationship between HIV-specific CTL activity and maintenance of peripheral blood CD4+ T lymphocyte counts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8edc68ffc65684f23b0d517f488335b
https://doi.org/10.1089/088922299310313

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Development of Calibrated Viral Load Standards for Group M Subtypes of Human Immunodeficiency Virus Type 1 and Performance of an Improved AMPLICOR HIV-1 MONITOR Test with Isolates of Diverse Subtypes

Autor: Merlin L. Robb, Shirley Kwok, Karen K. Y. Young, John R. Mascola, Francine E. McCutchan, Steven A. Herman, Jean K. Carr, June Wang, Joanne Spadoro, Nelson L. Michael, Linda L. Jagodzinski, Kimberly Dreyer, Victoria R. Polonis, Cindy Christopherson

Publikováno v: Journal of Clinical Microbiology. 37:2557-2563

Accurate determination of plasma human immunodeficiency virus type 1 (HIV-1) RNA levels is critical for the effective management of HIV-1 disease. The AMPLICOR HIV-1 MONITOR Test, a reverse transcription-PCR-based test for quantification of HIV-1 RNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f2bc2c53b37c7dc7498891b1cd4a15
https://doi.org/10.1128/jcm.37.8.2557-2563.1999

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Virological and Immunological Features of Long-Term Human Immunodeficiency Virus–Infected Individuals Who Have Remained Asymptomatic Compared With Those Who Have Progressed to Acquired Immunodeficiency Syndrome

Autor: Gustavo Reyes-Teran, Jay A. Levy, Sheng-Yung Chang, Sue H. Fujimura, Sharon A. Stranford, Edward D. Barker, Carl E. Mackewicz, Cindy Christopherson, Akihiko Sato

Publikováno v: Blood. 92:3105-3114

Infection with the human immunodeficiency virus (HIV) leads to a decrease in CD4+ T cells and disease progression within a decade of seroconversion. However, a small group of infected people, despite being infected by HIV for 10 or more years, remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92295ab698934de604bed58cc369354c
https://doi.org/10.1182/blood.v92.9.3105

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