Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Cindy Casaceli"'
Autor:
Tanya Simuni, Holly A. Shill, Matthew Brodsky, Marcie Rabin, Michael A. Schwarzschild, Kenneth Marek, Cheryl Waters, Cindy Casaceli, Steven A. Gunzler, Stephen G. Reich, Codrin Lungu, Sarah Elizabeth Zauber, Kellie Keith, Shyamal H. Mehta, Dariush Mozaffarian, Valerie Suski, Marie Saint-Hilaire, John L. Goudreau, Alice Rudolph, Ruth B. Schneider, Aaron Daley, Eric A. Macklin, Zoltan Mari, Grace F. Crotty, Andres Deik, Alberto J. Espay, Ashley Laroche, Sherri Mosovsky, Joohi Jimenez-Shahed, Mark S. LeDoux, Cynthia Poon, Ashley Gerald, John C. Morgan, Carolyn Peterson, Joseph H. Friedman, David Klements, Robert A. Hauser, Doozie Russell, David Simon, Kathrin LaFaver, Vanessa K. Hinson, Richard B. Dewey, Melissa Ainslie, Jason Aldred, Tiago A. Mestre, John Y. Fang, Liana S. Rosenthal, Grace Bwala, Raymond C. James, Binit B. Shah, Gearoid M. McMahon, Ariane Park, Rajeev Kumar, Lin Zhang, Ivan Bodis-Wollner, Mya C. Schiess, Katherine F. Callahan, David Oakes, Kelvin L. Chou, Melissa Kostrzebski, Roger Kurlan, Lisa Gauger, Albert Y. Hung, Melissa Bixby, Ira Shoulson, Michael Soileau, James T. Boyd, Peter A LeWitt, Burton L. Scott, Claire Henchcliffe, Patricia Kaminski, Alberto Ascherio, Cornelia Kamp, Lindsay Pothier, Anwar Ahmed, Jill Ciccarello, David J. Houghton, April Langhammer, Rebecca Fitzgerald, Maureen A. Leehey, Anthony E. Lang, Carmen Serrano, Martha McGraw, David Shprecher, Jennifer Durphy, Aleksandar Videnovic, Danish Bhatti, Christine Hunter, Amber Servi Ratel, J. Antonelle de Marcaida, Christopher G. Goetz, Emily Houston, Rajesh Pahwa, Chadwick W. Christine, Gary C. Curhan, Irene Litvan, Christopher A. Beck, Leslie J. Cloud, Patrick Bolger, Karen Thomas, Natividad Stover, Karen Blindauer, Sushrut S. Waikar, Susan R. Criswell
Publikováno v:
JAMA
IMPORTANCE: Urate elevation, despite associations with crystallopathic, cardiovascular, and metabolic disorders, has been pursued as a potential disease-modifying strategy for Parkinson disease (PD) based on convergent biological, epidemiological, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4608ea519947a922d23da1991ccca9
https://europepmc.org/articles/PMC8441591/
https://europepmc.org/articles/PMC8441591/
Autor:
Jaime Adams, Samuel Frank, Deborah Baker, Saurav Brahmachari, Elizabeth A. Klingner, Jason Aldred, Jennifer Mule, Meredith Spindler, Cornelia Kamp, Phounsavath Muneath, Claudia Rocha, Liana Baker, Gian Pal, Doozie Russell, Yvette Pitchford, Tina Ward, Olga Kishchenko, Kellie Keith, Angela S Stovall, Courtney Blair, John Slevin Slevin, Vanessa K. Hinson, Grace Bwala, Brian K. Fiske, Liana S. Rosenthal, Joohi Shahed, Andrew P. Duker, Patrick Bolger, Gary Rafaloff, David Weiner, Adolfo Ramirez-Zamora, Zoltan Mari, Renee Wagner Wagner, Helen Matthews, Karen Blindauer, Derek B. Ridgeway, Alexandria Oliver, Carlinda Field, Stephanie Burrows, Binit B. Shah, Lauren Seeberger, Charles S. Venuto, Katie Sullivan, Laura Ramirez, Erika F. Augustine, Matthew Swan, Lilliana Dumitrescu, Natividad Stover, Shonna Jenkins, Sharon Evans, Lin Zhang, Anwar Ahmed, Tanya Simuni, Michael A. Schwarzschild, Christopher S. Coffey, Mark S. LeDoux, David-Erick Lafontant, Laura Trusso, Farah Ismail, John L. Goudreau, Eric Molho, Sue Henderson, Cindy Casaceli, Christine Hunter, Holly Reynolds, Albert Y. Hung, Robert A. Hauser, Burton L. Scott, Lynn Wheeler, Kalpana Merchant, Chelsea Caspell-Garcia, Claire E. Wegel, Richard K. Wyse, Patrik Brundin, Christina Gruenwald, Alicia Brocht, Candace Cromer, Lisa Gauger, Melissa Bixby, Emily Carman, Kathryn A. Chung, Nichole McMullen, David Simon, Ken Eaton, Oren A. Levy, Amber Servi, Abigail Simpson, Holly A. Shill, Kelvin L. Chou, Melissa Kostrzebski, Ted M. Dawson
Publikováno v:
JAMA Neurology. 78:312
Importance There is a critical need for careful and independent validation of reported symptomatic efficacy and dopaminergic biomarker changes induced by nilotinib in Parkinson disease (PD). Objectives To assess safety and tolerability of nilotinib i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da5bef13be163263b4f128491abd097
https://doi.org/10.1001/jamaneurol.2020.4725
https://doi.org/10.1001/jamaneurol.2020.4725
Autor:
Catherine Kopil, Katrina Gwinn, Amy W. Amara, Lona Vincent, Roy N. Alcalay, Cindy Casaceli, Howard Andrews, Penelope Hogarth, Un Jung Kang, Samuel Frank, Jennifer G. Goldman, Alice Rudolph, Mark Frasier, Paul J. Tuite, Claire Henchcliffe, Tao Xie, Margaret Sutherland
Publikováno v:
Movement Disorders
Movement disorders : official journal of the Movement Disorder Society, vol 31, iss 6
Movement disorders : official journal of the Movement Disorder Society, vol 31, iss 6
Background Identifying PD‐specific biomarkers in biofluids will greatly aid in diagnosis, monitoring progression, and therapeutic interventions. PD biomarkers have been limited by poor discriminatory power, partly driven by heterogeneity of the dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988422b54f10fd4b4c759b97cc01ceec
https://doi.org/10.1002/mds.26613
https://doi.org/10.1002/mds.26613
Autor:
Darren R. Feldman, Shirin Ardeshir-Rouhani-Fard, Patrick Monahan, Howard D. Sesso, Chunkit Fung, Annalynn M. Williams, Robert J. Hamilton, David J. Vaughn, Clair J. Beard, Ryan Cook, Mohammad Abu Zaid, Steven E. Lipshultz, Lawrence H. Einhorn, Kevin C. Oeffinger, Lois B. Travis, Sophie D. Fossa, Stephanie Curreri, Mary Jacqueline Brames, Kelli Norton, Erin Jacobsen, Deborah Silber, Rob Hamilton, Lynn Anson-Cartwright, Nancy J. Cox, M. Eileen Dolan, Linda Jacobs, Sarah Lena Panzer, Donna Pucci, Debbie Baker, Cindy Casaceli, Eileen Johnson, Deepak Sahasrabudhe, Robert D. Frisina, George Bosl, Mary Gospodarowicz, Leslie L. Robison
Publikováno v:
Clinical genitourinary cancer. 16(4)
Testicular cancer survivors are at increased risk of cardiovascular disease after cisplatin-based chemotherapy. Among 787 testicular cancer survivors, the Framingham Risk Score for cardiovascular disease was elevated among less educated and less vigo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d53dde1a90fdc79581c924b7977371b
https://pubmed.ncbi.nlm.nih.gov/29534941
https://pubmed.ncbi.nlm.nih.gov/29534941
Autor:
Bernard, Ravina, Caroline, Tanner, Diane, Dieuliis, Shirley, Eberly, Emily, Flagg, Wendy R, Galpern, Stanley, Fahn, Christopher G, Goetz, Stephen, Grate, Roger, Kurlan, Anthony E, Lang, Kenneth, Marek, Karl, Kieburtz, David, Oakes, Robin, Elliott, Ira, Shoulson, Cindy, Casaceli
Publikováno v:
Movement Disorders. 24:2081-2090
Long-term follow up is necessary to understand the natural history of treated Parkinson's disease (PD). The Longitudinal and Biomarker Study in PD (LABS-PD) is an observational study designed to prospectively measure the evolution of motor and non-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf4bb76ed253ec54dea1db18c41c80d
https://doi.org/10.1002/mds.22690
https://doi.org/10.1002/mds.22690
Autor:
Michael K. Lee, Cindy Casaceli, Gretchen L. Kiser, Tamma Kaysser-Kranich, Howard J. Federoff, Renee M. Miller, Chockalingham Palaniappan, Emanuela Colla
Publikováno v:
Experimental Neurology. 204:421-432
The pathophysiological processes that cause Parkinson's disease (PD) affect dopamine neurons residing in the substantia nigra with devastating consequences for normal movement. One important gene involved in both familial and sporadic PD is alpha-syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf6a3916f493829acdefc483be6e3a0
https://doi.org/10.1016/j.expneurol.2006.12.005
https://doi.org/10.1016/j.expneurol.2006.12.005
Publikováno v:
Annals of the New York Academy of Sciences. 991:315-318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f32070b7fc4d747406ae6e2a6d75f7d3
https://doi.org/10.1111/j.1749-6632.2003.tb07494.x
https://doi.org/10.1111/j.1749-6632.2003.tb07494.x
Autor:
Martha Nance, Izelle Labuschagne, Karen Marder, C. Herd, Mays A. El-Dairi, Scott R. Evans, A. Daley, Henry Moore, Phyllis Chua, Jody Corey-Bloom, S. Targum, Patrick Mitchell, Jody Goldstein, David Ames, Rajeev Ananda Kumar, H. Mack, Eric Molho, S. Wray, Susan R. Criswell, Carlos Singer, Ronda Clouse, Anita M.Y. Goh, Karen Anderson, Andrew Feigin, David Oakes, Jane Griffith, Peter K. Panegyres, Carr J. Vaughan, Alessandro Iannaccone, Andrew Churchyard, Leah Levi, Craig W. Ritchie, Russell L. Margolis, D. L. Lim, Nadine Yoritomo, Barbara J. Jennings, Cameron Stone, Vicki Sergo, Constance Orme, Sarah Janicki, D. Angus, K. Helles, H. D. Rosas, Ralf Reilmann, Carolyn M. Drazinic, Arthur Watts, B. Hennig, Shea Gluhm, Sharon Fekrat, Sandra K. Kostyk, Earl Ray Dorsey, M. Moscovitch-Lopatin, Mark S. LeDoux, S. Gao, R. Ranzi, N. Padron, Elise Kayson, Shannon Guyot, K. Baker, Pinky Agarwal, Clement T. Loy, Marguerite Wieler, Steven M. Hersch, Cindy Casaceli, M. Murathodizic, Julie C. Stout, Blair R. Leavitt, D. Germaine
Publikováno v:
The Lancet. Neurology. 14(1)
Background: PBT2 is a metal protein-attenuating compound that might reduce metal-induced aggregation of mutant huntingtin and has prolonged survival in a mouse model of Huntington's disease. We aimed to assess the safety, tolerability, and efficacy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061c6b2c50c34a60674732abb8ba1f5c
https://pubmed.ncbi.nlm.nih.gov/25467849
https://pubmed.ncbi.nlm.nih.gov/25467849
Autor:
Lawrence Elmer, McGuire D, Janis M. Miyasaki, Pierre N. Tariot, Cynthia L. Comella, Rajesh Pahwa, S. Schuman, Margaret C. Lannon, James W. Tetrud, Wiener W, Christopher Cox, Oksana Suchowersky, Wratni E, Lucia M. Blasucci, Chase T, Greenamyre Jt, Karen Hodgeman, Deleo A, Michael P. McDermott, Carrion A, Panniset M, Paula D. Ryan, Robert A. Hauser, Johnston L, Bateman-Rodriguez D, Amy Colcher, Baker D, Mistura K, Andrew Siderowf, W.R. Wayne Martin, Peggy Gray, Constance Orme, Jeffrey Friedlander, Charles H. Adler, Dilllon S, Stanley Fahn, Eric Siemers, David Grimes, Lauren Seeberger, M. Brewer, Colleen Dingmann, Frey J, Holdich T, Cooper J, Mark Stacy, Stewart A. Factor, Daniel Tarsy, Kennedy L, McCree L, Mary Lloyd, J. B. Penney, Lisa Gauger, Pantella C, Arthur Watts, Kenneth Marek, John P. Hammerstad, Matthews M, Kimberly Janko, Diane Brown, Denni Day, McDermott J, Sulimowicz K, Ruzicka D, Marsha Tennis, Bardram K, Joann Belden, Madaline B. Harrison, Blair Ford, Davies R, Mark F. Lew, Alderfer, Jennifer Mazurkiewicz, Elise Kayson, Broshjeit S, Rexo L, Andrew Feigin, Craun Am, Cha Jh, C. Stone, Stephanie Newman, Nirupama Laroia, Jean Hall, Ira Shoulson, Peter A LeWitt, Read B, Robert L. Rodnitzky, Danna Jennings, Judith Dobson, Lang A, Florack M, Nobel R, Steven R. Schwid, Leventhal C, A. L. Lafontaine, Nancy Pearson, Lawrence N. Shulman, Rothenburgh K, Rost E, Locke B, Cindy Casaceli
Publikováno v:
Neurology. 56:455-462
Background Preclinical studies suggest that glutamate antagonists help ameliorate motor fluctuations in patients with PD treated with levodopa. Methods In a multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d568a8ad50ad99173f553a65cfb0dde5
https://doi.org/10.1212/wnl.56.4.455
https://doi.org/10.1212/wnl.56.4.455
Autor:
Alberto J. Espay, David J. Irwin, Arita McCoy, Madelaine Ranola, Giulia Malferrari, Angela James, Stuart Isaacson, Caroline M. Tanner, Peggy Taylor, Laura Leary, Emily Pighetti, Abigail Darin, Brit Mollenhauer, Christine Hunter, Sohini Chowdhury, Dominic B. Rowe, Danna Jennings, Andrew Siderowf, Zoltan Mari, Jon W. Yankey, Shirley Lasch, Hubert H. Fernandez, Arthur W. Toga, Ju-Hee Kang, Robert A. Hauser, Leslie M. Shaw, Daniela Berg, Diana Willeke, Katharina Gauss, John Seibyl, Keith A. Hawkins, David Standaert, Liz Uribe, Kristy J. Espay, Karen Williams, Holly A. Shill, Alice Chen-Plotkin, Sam Frank, Paola Casalin, Douglas Galasko, Werner Poewe, Cindy Casaceli, Fabienne Sprenger, Karen Crawford, Wolfgang Oertel, Joseph Jankovic, Andrew B. Singleton, Alison Scutti, Paolo Barone, Sarah Pan, Deborah Fontaine, Alice Rudolph, Barbara Sommerfeld, David Brooks, Bina Shah, Teresa Waligorska, James B. Leverenz, Matthew B. Stern, Stewart A. Factor, Karl Kieburtz, Christopher S. Coffey, John Q. Trojanowski, Penelope Hogarth, Kenneth Marek, Norbert Schuff, Susan Mendick, Linda Rees, Cathi-Ann Thomas, Marne Baca, Todd Sherer, Mark Frasier, Tanya Simuni, Stephanie Guthrie, David W. Russell, Claire Meunier, Jennifer Mule, Cheryl Deeley, Emily Flagg, Irene Richard, Chelsea Caspell
Publikováno v:
JAMA Neurology.
Importance We observed a significant correlation between cerebrospinal fluid (CSF) levels of tau proteins and α-synuclein, but not β-amyloid 1-42 (Aβ1-42), and lower concentration of CSF biomarkers, as compared with healthy controls, in a cohort o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5a2b105421417b8b73f5904b040220
https://doi.org/10.1001/jamaneurol.2013.3861
https://doi.org/10.1001/jamaneurol.2013.3861