Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cindy C. Lu"'
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004823 (2014)
Tonotopy is a fundamental organizational feature of the auditory system. Sounds are encoded by the spatial and temporal patterns of electrical activity in spiral ganglion neurons (SGNs) and are transmitted via tonotopically ordered processes from the
Externí odkaz:
https://doaj.org/article/2b6c766867114ffaa29b14709a99a31b
Autor:
Lisa V. Goodrich, Wei-Ming Yu, Jessica M. Appler, Cindy C. Lu, Noah R. Druckenbrod, Edmund J. Koundakjian
Publikováno v:
The Journal of Neuroscience. 33:3679-3691
Spiral ganglion neurons (SGNs) play a key role in hearing by rapidly and faithfully transmitting signals from the cochlea to the brain. Identification of the transcriptional networks that ensure the proper specification and wiring of SGNs during deve
Publikováno v:
Journal of Neuroscience. 31:10903-10918
The sense of hearing depends on the faithful transmission of sound information from the ear to the brain by spiral ganglion (SG) neurons. However, how SG neurons develop the connections and properties that underlie auditory processing is largely unkn
Autor:
Daniel Mesnard, Luca Pescatore, Nadav Ben-Haim, Cindy C. Lu, Daniel B. Constam, Elizabeth J. Robertson, Felix Naef, Mirko Bischofberger, Marcela Guzman-Ayala
Publikováno v:
Developmental Cell. 11(3):313-323
During early mouse development, the subtilisin-like proprotein convertases (SPC) Furin and PACE4 pattern the primitive ectoderm and visceral endoderm, presumably by activating the TGFss-related Nodal precursor. Here, mutation of the SPC motif provide
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004823 (2014)
PLoS Genetics
PLoS Genetics
Tonotopy is a fundamental organizational feature of the auditory system. Sounds are encoded by the spatial and temporal patterns of electrical activity in spiral ganglion neurons (SGNs) and are transmitted via tonotopically ordered processes from the
Autor:
Cindy C. Lu, Elizabeth J. Robertson
Publikováno v:
Developmental Biology. 273(1):149-159
The TGFβ family member Nodal has been shown to be involved in a variety of processes in development, including early axis formation. Here, we use a conditional gene inactivation strategy to show a specific requirement for Nodal in the epiblast. Comp
Publikováno v:
Developmental Biology. 319(2)
Publikováno v:
Gene expression patterns : GEP. 4(5)
Wnt signaling has been shown to be important for axis formation in vertebrates. However, no Wnt ligand or receptor has been shown to be specifically expressed in all the organizer tissues in the mouse embryo. Here we report that the mouse frizzled 8
Publikováno v:
Current opinion in geneticsdevelopment. 11(4)
Although much remains unknown about how the embryonic axis is laid down in the mouse, it is now clear that reciprocal interactions between the extraembryonic and embryonic lineages establish and reinforce patterning of the embryo. At early post-impla
Autor:
Elizabeth J. Robertson, Rosa S.P Beddington, Tristan A. Rodriguez, Jane Brennan, Dominic P. Norris, Cindy C. Lu
Publikováno v:
Nature. 411(6840)
Shortly after implantation the mouse embryo comprises three tissue layers. The founder tissue of the embryo proper, the epiblast, forms a radially symmetric cup of epithelial cells that grows in close apposition to the extra-embryonic ectoderm and th