Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Cindy, Yun"'
Autor:
Daniel M. Halperin, Gauri R. Varadhachary, James C. Yao, Scott E. Woodman, Keith F. Fournier, Scott Kopetz, Ajaykumar C. Morani, Walter C. Darbonne, Katja Schulze, Shannon Dervin, Cindy Yun, Edward McKenna, Patricia Cortazar, Patrick Hwu, Armeen Mahvash, Anuj Verma, Pamela Villalobos, Honglei Chen, Edwin R. Parra Cuentas, Luisa M. Solis Soto, Dipen M. Maru, Andrew P. Futreal, Ignacio I. Wistuba, Paul F. Mansfield, Christopher P. Scally, Richard E. Royal, Seema Prasad, Anais Malpica, Szu-Chin Fu, Mark Knafl, Anneleis F. Willett, Michael J. Overman, Suyu Liu, Kanwal Raghav
Malignant peritoneal mesothelioma (MPeM) is a rare but aggressive malignancy with limited treatment options. VEGF inhibition enhances efficacy of immune-checkpoint inhibitors by reworking the immunosuppressive tumor milieu. Efficacy and safety of com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810c1697e03dca3033be01a2d214aa5c
https://doi.org/10.1158/2159-8290.c.6549433.v1
https://doi.org/10.1158/2159-8290.c.6549433.v1
Autor:
Edward S. Kim, Vamsidhar Velcheti, Tarek Mekhail, Cindy Yun, Sarah M. Shagan, Sylvia Hu, Young Kwang Chae, Ticiana A. Leal, Jonathan E. Dowell, Michaela L. Tsai, Christopher S. R. Dakhil, Philip Stella, Yanling Jin, David S. Shames, Erica Schleifman, David A. Fabrizio, See Phan, Mark A. Socinski
Publikováno v:
Nature Medicine. 28:939-945
Tumor mutational burden (TMB) in circulating tumor DNA (ctDNA) has shown promise in predicting benefit from PD-L1/PD-1 inhibitors in retrospective studies. Aiming to assess blood TMB (bTMB) prospectively, we conducted B-F1RST (NCT02848651), an open-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6af5f44d27b1e8f0cd1b472e336e4278
https://doi.org/10.1038/s41591-022-01754-x
https://doi.org/10.1038/s41591-022-01754-x
Autor:
Daniel M. Halperin, Suyu Liu, Arvind Dasari, David Fogelman, Priya Bhosale, Armeen Mahvash, Jeannelyn S. Estrella, Laura Rubin, Ajaykumar C. Morani, Mark Knafl, Tim A. Overeem, Szu-Chin Fu, Luisa M. Solis, Edwin Parra Cuentas, Anuj Verma, Hong-Lei Chen, Swati Gite, Priya Subashchandrabose, Shannon Dervin, Katja Schulze, Walter C. Darbonne, Cindy Yun, Ignacio I. Wistuba, P. Andrew Futreal, Scott E. Woodman, James C. Yao
Publikováno v:
JAMA Oncol
IMPORTANCE: Therapies for patients with advanced well-differentiated neuroendocrine tumors (NETs) have expanded but remain inadequate, with patients dying of disease despite recent advances in NET therapy. While patients with other cancers have seen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dddac8d2ce3b68691ad8b930d043467
https://europepmc.org/articles/PMC8990358/
https://europepmc.org/articles/PMC8990358/
Autor:
P.A. Ascierto, A. Tan, R. Walls, Cindy Yun, Q. Zhang, J. Reddy, M.H. Secrest, I. Ngwa, K. Sarsour, P. Lambert, A. Seetasith, D. Shenison
Publikováno v:
Annals of Oncology
Background: We assessed mortality risk by COVID-19 (C19) infection among treated cancer patients (pts) and the impact of anti-cancer treatment (tx) on mortality. Methods: Optum de-identified Electronic Health Record dataset (2021-01-07 release) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad770be71139e4479c552de685397656
http://europepmc.org/articles/PMC8454377
http://europepmc.org/articles/PMC8454377
Autor:
Cindy Yun, Edwin R. Parra, John DeGroot, Victory Joseph, Ignacio I. Wistuba, Rebecca Harrison, Woodman Scott, Luisa M. Solis, Mark Knafl, Barbara O’Brien, Shiao-Pei Weathers, Carlos Kamiya-Matsuoka, Nazanin Majd, Andrew Futreal, Beatriz Sanchez Espiridion, Dipen M. Maru, Sharia Hernandez, Marta Penas-Prado, Monica Loghin, Walter Darbonne, W. K. Alfred Yung
Publikováno v:
Neuro-Oncology. 23:vi49-vi49
BACKGROUND Checkpoint inhibitor therapy has demonstrated overall limited efficacy in the treatment of GBM. Mechanisms of resistance to checkpoint blockade need to be better elucidated. Analysis of the tumor microenvironment is critical to identify co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3497abd30d751c565e8f0068875ef8a4
https://doi.org/10.1093/neuonc/noab196.196
https://doi.org/10.1093/neuonc/noab196.196
Autor:
Diane Liu, Rebecca Harrison, Shannon Dervin, Monica Loghin, Barbara O’Brien, Edmund Sanqui, Shiao-Pei Weathers, W. K. Alfred Yung, Nazanin Majd, Cindy Yun, Marta Penas-Prado, John de Groot, Carlos Kamiya-Matsuoka
Publikováno v:
Neuro Oncol
BACKGROUND Immunotherapy strategies such as PD-1/PD-L1 inhibition may work synergistically with radiation, which is known to increase antigen presentation and promote a pro-inflammatory tumor microenvironment. This trial evaluated the safety and clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa65c31d9bdf993a19832d958f286268
https://doi.org/10.1093/neuonc/noaa215.145
https://doi.org/10.1093/neuonc/noaa215.145
Autor:
Daniel M. Halperin, Kanwal Pratap Singh Raghav, Scott Kopetz, Richard E. Royal, Michael J. Overman, Ignacio I. Wistuba, Anais Malpica, Edward McKenna, Cindy Yun, Armeen Mahvash, Andrew Futreal, Gauri R. Varadhachary, Shannon Dervin, Patrick Hwu, Katja Schulze, James C. Yao, Anneleis Willett, Christopher P. Scally, Suyu Liu
Publikováno v:
Journal of Clinical Oncology. 38:9013-9013
9013 Background: Malignant peritoneal mesothelioma (MPeM) is an orphan malignancy. No recommended/FDA approved therapies exist for salvage treatment beyond first-line platinum and pemetrexed based chemotherapy. While immune checkpoint inhibition has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23acba6f374a7728386b9469dea13da4
https://doi.org/10.1200/jco.2020.38.15_suppl.9013
https://doi.org/10.1200/jco.2020.38.15_suppl.9013
Autor:
Diane D. Liu, Nazanin Majd, Barbara O’Brien, Carlos Kamiya-Matsuoka, John de Groot, Monica Loghin, Marta Penas-Prado, Shiao-Pei Weathers, W. K. Alfred Yung, Rebecca Harrison, Shannon Dervin, Cindy Yun
Publikováno v:
Journal of Clinical Oncology. 38:2511-2511
2511 Background: Immunotherapy strategies such as PD-1/PD-L1 inhibition may work synergistically with radiation, which is known to increase antigen presentation and promote a pro-inflammatory tumor microenvironment. This trial evaluated the safety an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0b4ce9bcb2da7cda44a4a953bfbcc43
https://doi.org/10.1200/jco.2020.38.15_suppl.2511
https://doi.org/10.1200/jco.2020.38.15_suppl.2511
Autor:
Cindy Yun, Armeen Mahvash, Arvind Dasari, Shannon Dervin, David R. Fogelman, Edward McKenna, Katja Schulze, Patrick Hwu, P.A. Futreal, Daniel M. Halperin, Ignacio I. Wistuba, Dipen M. Maru, Jeannelyn S. Estrella, Walter C. Darbonne, Priya Bhosale, James C. Yao, Suyu Liu, Patricia Cortazar
Publikováno v:
Journal of Clinical Oncology. 38:619-619
619 Background: Neuroendocrine tumors (NETs) are relatively rare and heterogeneous tumors arising throughout the aerodigestive tract, which are incurable and life-limiting when metastatic. Prior studies of checkpoint inhibitors in NET patients have y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41aff7955efec093675c4767ff641b9f
https://doi.org/10.1200/jco.2020.38.4_suppl.619
https://doi.org/10.1200/jco.2020.38.4_suppl.619
Autor:
Ji Youn Han, Åslaug Helland, David R. Gandara, Keunchil Park, Toshio Kubo, J. Goldschmidt, Santiago Ponce Aix, Marcus Ballinger, Wei Yu, C. Matheny, Fabrice Barlesi, Alan Sandler, Richard Sullivan, M. Gandhi, Louis Fehrenbacher, Achim Rittmeyer, Joachim von Pawel, Cindy Yun, Julien Mazieres, Pei He
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 13(12)
Introduction Cancer immunotherapy may alter tumor biology such that treatment effects can extend beyond radiographic progression. In the randomized, phase III OAK study of atezolizumab (anti–programmed death-ligand 1) versus docetaxel in advanced N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f45bc4d232bed00729d4de352e44cc
https://pubmed.ncbi.nlm.nih.gov/30217492
https://pubmed.ncbi.nlm.nih.gov/30217492