An imbalance in the production of IL-1 beta and IL-6 by monocytes of bipolar patients: restoration by lithium treatment

Autor: Willem A. Nolen, Ralph Kupka, Grard W. Akkerhuis, Harm de Wit, Esther M. Knijff, Cindy Ruwhof, Hemmo A. Drexhage, M. Nadine Breunis

Publikováno v: Bipolar Disorders, 9(7), 743-753. Wiley
Bipolar Disorders, 9(7), 743-753. Blackwell Publishing
Knijff, E M, Nadine, B M, Kupka, R W, De Wit, H J, Ruwhof, C, Akkerhuis, G W, Nolen, W A & Drexhage, H A 2007, ' An imbalance in the production of IL-1β and IL-6 by monocytes of bipolar patients : Restoration by lithium treatment ', Bipolar Disorders, vol. 9, no. 7, pp. 743-753 . https://doi.org/10.1111/j.1399-5618.2007.00444.x
Bipolar Disorders, 9(7), 743-753. Blackwell Munksgaard

Objectives: To study the ex vivo interleukin (IL)-1 beta and IL-6 production of monocytes in bipolar disorder (BD) patients in the absence/presence of lithium. Methods: Monocytes of outpatients with DSM-IV BD (n = 80, of whom 64 were lithium-treated)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59c05e0bea96c3407e58c85bf12e8e1
https://research.rug.nl/en/publications/07f0d34f-689d-4346-b299-9abcd4914fec

Monocyte-derived dendritic cells in bipolar disorder

Autor: Willem A. Nolen, Cindy Ruwhof, Ronald Vonk, Ralph Kupka, Harm de Wit, Esther M. Knijff, Hemmo A. Drexhage, Grard W. Akkerhuis

Publikováno v: Biological Psychiatry, 59(4), 317-326. ELSEVIER SCIENCE INC
Knijff, E M, Ruwhof, C, De Wit, H J, Kupka, R W, Vonk, R, Akkerhuis, G W, Nolen, W A & Drexhage, H A 2006, ' Monocyte-derived dendritic cells in bipolar disorder ', Biological Psychiatry, vol. 59, no. 4, pp. 317-326 . https://doi.org/10.1016/j.biopsych.2005.06.041
Biological Psychiatry, 59(4), 317-326. Elsevier USA
Biological Psychiatry, 59(4), 317-326. Elsevier Inc.

Background: Dendritic cells (DC) are key regulators of the immune system, which is compromised in patients with bipolar disorder. We sought to study monocyte-derived DC in bipolar disorder.Methods: Monocytes purified from blood collected from DSM-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423489845da08107e6c4b6842bb09237
https://research.rug.nl/en/publications/89c459b5-220c-4a71-b13a-26c07b77fe29

1-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes

Autor: MO Canning, Cindy Ruwhof, K Grotenhuis, H.J. de Wit, Hemmo A. Drexhage

Publikováno v: European journal of endocrinology. 145(3)

OBJECTIVE: To study the effects of the active metabolite of vitamin D(3), 1,25(OH)(2)D(3), an immunomodulatory hormone, on the generation of so-called immature dendritic cells (iDCs) generated from monocytes (Mo-iDCs). DESIGN AND METHODS: Human perip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d23a52af5b8b21c6ec3db2630d24df
https://pubmed.ncbi.nlm.nih.gov/11517017

Role of fibroblasts in the regulation of proinflammatory interleukin IL-1, IL-6 and IL-8 levels induced by keratinocyte-derived IL-1

Autor: Ingeborg L.A. Boxman, Cindy Ruwhof, Clemens W.G.M. Löwik, Maria Ponec, Otto C. Boerman

Publikováno v: Archives of Dermatological Research, 288, pp. 391-398
Archives of Dermatological Research, 288, 391-398
Archives of Dermatological Research 288 (1996) 7
Archives of Dermatological Research, 288, 7, pp. 391-398
Archives of Dermatological Research, 288(7), 391-398

In the epidermis, the keratinocytes are the first cells to be encountered by external stimuli and they are able to promote the inflammatory response by increased production and release of various cytokines. In their turn, these cytokines may directly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2c4a5cc7bccf096396488d4a6ae935
https://hdl.handle.net/2066/188389